Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10898
Symbol

CPSF4

Synonymous

CPSF30|NAR|NEB1

Full name

cleavage and polyadenylation specific factor 4, 30kDa

Gene description

CPSF 30 kDa subunit|NS1 effector domain-binding protein 1|cleavage and polyadenylation specificity factor 30 kDa subunit|cleavage and polyadenylation specificity factor subunit 4|cleavage-polyadenylation specificity factor, 30kD|neb-1|no arches homolog|no

Cytoband

7q22.1

Gene type

protein-coding

Synonymous

MIM:603052; HGNC:HGNC:2327; Ensembl:ENSG00000160917; HPRD:04338; Vega:OTTHUMG00000154599

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.786C>A; p.H262Q; 7:99456476-99456476

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.600G>A; p.S200S; 7:99453995-99453995

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.112G>A; p.A38T; 7:99444797-99444797

 livercarcinomaSubstitution - Missense

c.112G>A; p.A38T; 7:99444797-99444797

 livercarcinomaSubstitution - Missense

c.763G>A; p.A255T; 7:99456453-99456453

 breastcarcinomaSubstitution - Missense

c.621G>A; p.T207T; 7:99454016-99454016

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.345C>T; p.I115I; 7:99450313-99450313

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.342C>T; p.H114H; 7:99450310-99450310

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.366G>T; p.K122N; 7:99450334-99450334

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.702C>T; p.N234N; 7:99454097-99454097

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.695C>T; p.A232V; 7:99454090-99454090

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.119T>C; p.V40A; 7:99444804-99444804

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.503G>A; p.R168Q; 7:99452373-99452373

 breastcarcinomaSubstitution - Missense

c.545C>A; p.P182Q; 7:99452415-99452415

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.302A>C; p.K101T; 7:99448268-99448268

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.472G>C; p.E158Q; 7:99450770-99450770

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.454C>T; p.L152F; 7:99450752-99450752

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.655C>A; p.P219T; 7:99454050-99454050

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.508G>C; p.E170Q; 7:99452378-99452378

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.99G>C; p.M33I; 7:99439181-99439181

 pancreascarcinomaSubstitution - Missense

c.457G>A; p.V153M; 7:99450755-99450755

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.284A>T; p.E95V; 7:99448250-99448250

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.670G>A; p.V224I; 7:99454065-99454065

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.747C>T; p.G249G; 7:99456437-99456437

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.747C>T; p.G249G; 7:99456437-99456437

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.217C>T; p.R73C; 7:99448183-99448183

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.260A>C; p.E87A; 7:99448226-99448226

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.260A>C; p.E87A; 7:99448226-99448226

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.655_656CC>AA; p.P219K; 7:99454050-99454051

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.546G>A; p.P182P; 7:99452416-99452416

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.129C>T; p.F43F; 7:99444814-99444814

 skinmalignant_melanomaSubstitution - coding silent

c.296A>C; p.Y99S; 7:99448262-99448262

 breastcarcinomaSubstitution - Missense

c.180C>T; p.I60I; 7:99448146-99448146

 pancreascarcinomaSubstitution - coding silent

c.136A>T; p.K46*; 7:99444821-99444821

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Nonsense

c.296A>G; p.Y99C; 7:99448262-99448262

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.413G>A; p.C138Y; 7:99450711-99450711

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.129C>G; p.F43L; 7:99444814-99444814

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.672C>T; p.V224V; 7:99454067-99454067

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.387T>C; p.R129R; 7:99450355-99450355

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.599C>T; p.S200L; 7:99453994-99453994

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.294C>A; p.F98L; 7:99448260-99448260

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.108G>A; p.S36S; 7:99444793-99444793

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.667G>A; p.G223R; 7:99454062-99454062

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.694G>A; p.A232T; 7:99454089-99454089

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.456C>T; p.L152L; 7:99450754-99450754

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.399G>A; p.K133K; 7:99450367-99450367

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.46G>C; p.E16Q; 7:99439128-99439128

 pancreascarcinomaSubstitution - Missense