lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1084
Symbol	CEACAM3
Synonymous	CD66D\|CEA\|CGM1\|W264\|W282
Full name	carcinoembryonic antigen-related cell adhesion molecule 3
Gene description	CD66d antigen\|carcinoembryonic antigen CGM1\|carcinoembryonic antigen gene family member 1\|nonspecific cross-reacting antigen
Cytoband	19q13.2
Gene type	protein-coding
Synonymous	MIM:609142; HGNC:HGNC:1815; Ensembl:ENSG00000170956; HPRD:16450; Vega:OTTHUMG00000150142

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.328C>T; p.Q110*; 19:41797852-41797852	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.241G>A; p.G81R; 19:41797765-41797765	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.90G>T; p.P30P; 19:41797614-41797614	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.397G>A; p.E133K; 19:41797921-41797921	breast	carcinoma	Substitution - Missense
c.280G>A; p.A94T; 19:41797804-41797804	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.280G>A; p.A94T; 19:41797804-41797804	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.280G>A; p.A94T; 19:41797804-41797804	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.303A>G; p.I101M; 19:41797827-41797827	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.474C>T; p.T158T; 19:41808862-41808862	skin; nipple	malignant_melanoma	Substitution - coding silent
c.319C>T; p.L107L; 19:41797843-41797843	skin	malignant_melanoma	Substitution - coding silent
c.293G>A; p.R98Q; 19:41797817-41797817	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.135C>T; p.V45V; 19:41797659-41797659	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.318C>T; p.S106S; 19:41797842-41797842	skin	malignant_melanoma	Substitution - coding silent
c.637C>T; p.L213F; 19:41810841-41810841	skin	malignant_melanoma	Substitution - Missense
c.126G>A; p.P42P; 19:41797650-41797650	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.126G>A; p.P42P; 19:41797650-41797650	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.276G>A; p.G92G; 19:41797800-41797800	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.119C>T; p.S40F; 19:41797643-41797643	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.276G>A; p.G92G; 19:41797800-41797800	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.241G>T; p.G81*; 19:41797765-41797765	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.567G>A; p.K189K; 19:41809989-41809989	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.641C>A; p.S214Y; 19:41810845-41810845	breast	carcinoma	Substitution - Missense
c.415C>T; p.H139Y; 19:41797939-41797939	skin	malignant_melanoma	Substitution - Missense
c.385C>T; p.L129F; 19:41797909-41797909	skin	malignant_melanoma	Substitution - Missense
c.254G>A; p.G85E; 19:41797778-41797778	skin	malignant_melanoma	Substitution - Missense
c.460G>A; p.A154T; 19:41808848-41808848	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.123G>A; p.M41I; 19:41797647-41797647	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.126G>T; p.P42P; 19:41797650-41797650	ovary	other; neoplasm	Substitution - coding silent
c.307A>C; p.T103P; 19:41797831-41797831	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.495G>A; p.A165A; 19:41808883-41808883	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.755C>T; p.S252F; 19:41811233-41811233	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.755C>T; p.S252F; 19:41811233-41811233	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.755C>T; p.S252F; 19:41811233-41811233	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.654C>T; p.A218A; 19:41810858-41810858	liver	carcinoma	Substitution - coding silent
c.609C>T; p.S203S; 19:41810336-41810336	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.654C>T; p.A218A; 19:41810858-41810858	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.581A>G; p.Q194R; 19:41810003-41810003	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.561_562CC>TT; p.L188F; 19:41809983-41809984	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.507G>A; p.A169A; 19:41808895-41808895	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.507G>A; p.A169A; 19:41808895-41808895	thyroid	other; neoplasm	Substitution - coding silent
c.464G>A; p.G155D; 19:41808852-41808852	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.694G>A; p.E232K; 19:41811172-41811172	liver	carcinoma	Substitution - Missense
c.599G>A; p.R200H; 19:41810326-41810326	bone; humerus	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.526C>T; p.L176F; 19:41808914-41808914	skin	malignant_melanoma	Substitution - Missense
c.679G>A; p.A227T; 19:41810883-41810883	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.549C>G; p.S183R; 19:41809971-41809971	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.7C>G; p.P3A; 19:41796684-41796684	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.619G>A; p.A207T; 19:41810346-41810346	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>T; p.P149S; 19:41808833-41808833	skin	malignant_melanoma	Substitution - Missense
c.445C>T; p.P149S; 19:41808833-41808833	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.25C>T; p.H9Y; 19:41796702-41796702	skin	malignant_melanoma	Substitution - Missense
c.621C>A; p.A207A; 19:41810348-41810348	prostate	carcinoma	Substitution - coding silent
c.25C>T; p.H9Y; 19:41796702-41796702	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.488G>T; p.G163V; 19:41808876-41808876	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.728G>A; p.R243Q; 19:41811206-41811206	skin	malignant_melanoma	Substitution - Missense
c.424C>T; p.Q142*; 19:41797948-41797948	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.728G>A; p.R243Q; 19:41811206-41811206	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.440G>T; p.G147V; 19:41808828-41808828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.567G>T; p.K189N; 19:41809989-41809989	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.628-1G>A; p.?; 19:41810831-41810831	skin	malignant_melanoma	Unknown
c.474C>A; p.T158T; 19:41808862-41808862	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.380C>T; p.S127L; 19:41797904-41797904	skin	malignant_melanoma	Substitution - Missense
c.54T>C; p.L18L; 19:41796731-41796731	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.347A>C; p.D116A; 19:41797871-41797871	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.291_317del27; p.R98_S106delRETIYTNAS; 19:41797815-41797841	stomach	carcinoma; adenocarcinoma	Deletion - In frame
c.580C>A; p.Q194K; 19:41810002-41810002	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.277G>C; p.A93P; 19:41797801-41797801	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.277G>C; p.A93P; 19:41797801-41797801	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.290G>A; p.G97D; 19:41797814-41797814	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.755C>A; p.S252Y; 19:41811233-41811233	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.446C>A; p.P149H; 19:41808834-41808834	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.133G>A; p.V45I; 19:41797657-41797657	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.279C>T; p.A93A; 19:41797803-41797803	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.727C>T; p.R243W; 19:41811205-41811205	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.165C>T; p.V55V; 19:41797689-41797689	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.165C>T; p.V55V; 19:41797689-41797689	skin	malignant_melanoma	Substitution - coding silent
c.507G>C; p.A169A; 19:41808895-41808895	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation