Cancer metastasis database

Annotation category 5

Gene information

Gene ID 1081
Symbol

CGA

Synonymous

CG-ALPHA|FSHA|GPHA1|GPHa|HCG|LHA|TSHA

Full name

glycoprotein hormones, alpha polypeptide

Gene description

FSH-alpha|LSH-alpha|TSH-alpha|anterior pituitary glycoprotein hormones common subunit alpha|choriogonadotropin alpha chain|chorionic gonadotrophin subunit alpha|chorionic gonadotropin, alpha polypeptide|follicle-stimulating hormone alpha chain|follicle-st

Cytoband

6q12-q21

Gene type

protein-coding

Synonymous

MIM:118850; HGNC:HGNC:1885; Ensembl:ENSG00000135346; HPRD:00342; Vega:OTTHUMG00000015161

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.275T>C; p.V92A; 6:87085832-87085832

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.92G>A; p.C31Y; 6:87086431-87086431

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.92G>A; p.C31Y; 6:87086431-87086431

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.263C>A; p.S88*; 6:87086260-87086260

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.340C>A; p.H114N; 6:87085767-87085767

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.229G>A; p.V77I; 6:87086294-87086294

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.229G>A; p.V77I; 6:87086294-87086294

 large_intestine; colonNSSubstitution - Missense

c.77C>T; p.P26L; 6:87088124-87088124

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.229G>A; p.V77I; 6:87086294-87086294

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.314C>T; p.A105V; 6:87085793-87085793

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.35T>C; p.L12P; 6:87088166-87088166

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.287G>C; p.G96A; 6:87085820-87085820

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.47C>T; p.S16L; 6:87088154-87088154

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.89-1G>A; p.?; 6:87086435-87086435

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.192A>T; p.P64P; 6:87086331-87086331

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.89-2A>G; p.?; 6:87086436-87086436

 lungcarcinoma; adenocarcinomaUnknown

c.112G>A; p.E38K; 6:87086411-87086411

 skinmalignant_melanomaSubstitution - Missense

c.135G>T; p.P45P; 6:87086388-87086388

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.311C>T; p.T104M; 6:87085796-87085796

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.249C>T; p.C83C; 6:87086274-87086274

 bone; femurchondrosarcomaSubstitution - coding silent

c.338A>T; p.Y113F; 6:87085769-87085769

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.210G>A; p.T70T; 6:87086313-87086313

 breastcarcinomaSubstitution - coding silent

c.3G>A; p.M1I; 6:87088198-87088198

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2T>C; p.M1T; 6:87088199-87088199

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.179C>A; p.A60E; 6:87086344-87086344

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.204G>A; p.K68K; 6:87086319-87086319

 skinmalignant_melanomaSubstitution - coding silent

c.176G>A; p.R59K; 6:87086347-87086347

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.105G>T; p.T35T; 6:87086418-87086418

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.130C>A; p.Q44K; 6:87086393-87086393

 skinmalignant_melanomaSubstitution - Missense

c.272G>T; p.R91M; 6:87086251-87086251

 NSNSSubstitution - Missense

c.45G>A; p.L15L; 6:87088156-87088156

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.315G>A; p.A105A; 6:87085792-87085792

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.224A>C; p.K75T; 6:87086299-87086299

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.73G>T; p.A25S; 6:87088128-87088128

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.73G>T; p.A25S; 6:87088128-87088128

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense