Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10663
Symbol

CXCR6

Synonymous

BONZO|CD186|STRL33|TYMSTR

Full name

chemokine (C-X-C motif) receptor 6

Gene description

C-X-C chemokine receptor type 6|CDw186|CXC-R6|CXCR-6|G protein-coupled receptor|G-protein coupled receptor STRL33|G-protein coupled receptor bonzo

Cytoband

3p21

Gene type

protein-coding

Synonymous

MIM:605163; HGNC:HGNC:16647; Ensembl:ENSG00000172215; HPRD:05520; Vega:OTTHUMG00000133448

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.320G>A; p.G107D; 3:45946801-45946801

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.346T>C; p.S116P; 3:45946827-45946827

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.532C>A; p.L178I; 3:45947013-45947013

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.96C>T; p.V32V; 3:45946577-45946577

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.38G>C; p.S13T; 3:45946519-45946519

 pancreascarcinomaSubstitution - Missense

c.250C>T; p.L84L; 3:45946731-45946731

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.378T>C; p.D126D; 3:45946859-45946859

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.574C>T; p.L192F; 3:45947055-45947055

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.675G>A; p.Q225Q; 3:45947156-45947156

 skinmalignant_melanomaSubstitution - coding silent

c.411C>T; p.A137A; 3:45946892-45946892

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.36C>G; p.F12L; 3:45946517-45946517

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.887G>A; p.R296Q; 3:45947368-45947368

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.887G>A; p.R296Q; 3:45947368-45947368

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.213G>A; p.V71V; 3:45946694-45946694

 skinmalignant_melanomaSubstitution - coding silent

c.828C>T; p.I276I; 3:45947309-45947309

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.74A>G; p.D25G; 3:45946555-45946555

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.829G>A; p.A277T; 3:45947310-45947310

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.829G>A; p.A277T; 3:45947310-45947310

 ovarycarcinomaSubstitution - Missense

c.829G>A; p.A277T; 3:45947310-45947310

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.829G>A; p.A277T; 3:45947310-45947310

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.600C>T; p.F200F; 3:45947081-45947081

 thyroidother; neoplasmSubstitution - coding silent

c.198G>A; p.T66T; 3:45946679-45946679

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.443G>C; p.G148A; 3:45946924-45946924

 livercarcinomaSubstitution - Missense

c.255C>T; p.P85P; 3:45946736-45946736

 skinmalignant_melanomaSubstitution - coding silent

c.835C>T; p.L279L; 3:45947316-45947316

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.935T>C; p.L312P; 3:45947416-45947416

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.319G>A; p.G107S; 3:45946800-45946800

 skinmalignant_melanomaSubstitution - Missense

c.933delC; p.V314fs*>29; 3:45947414-45947414

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.365G>A; p.C122Y; 3:45946846-45946846

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.626T>C; p.V209A; 3:45947107-45947107

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.934C>T; p.L312F; 3:45947415-45947415

 skinmalignant_melanomaSubstitution - Missense

c.464T>C; p.I155T; 3:45946945-45946945

 breastcarcinomaSubstitution - Missense