| Gene ID | 10551 |
| Symbol | AGR2 |
| Synonymous | AG2|GOB-4|HAG-2|HEL-S-116|PDIA17|XAG-2 |
| Full name | anterior gradient 2 |
| Gene description | AG-2|HPC8|anterior gradient homolog 2|anterior gradient protein 2 homolog|epididymis secretory protein Li 116|protein disulfide isomerase family A, member 17|secreted cement gland homolog|secreted cement gland protein XAG-2 homolog |
| Cytoband | 7p21.3 |
| Gene type | protein-coding |
| Synonymous | MIM:606358; HGNC:HGNC:328; Ensembl:ENSG00000106541; HPRD:05896; Vega:OTTHUMG00000023446 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.264G>A; p.K88K; 7:16799810-16799810 |
skin | malignant_melanoma | Substitution - coding silent |
c.308A>G; p.Q103R; 7:16799766-16799766 |
thyroid | carcinoma | Substitution - Missense |
c.75C>T; p.V25V; 7:16801722-16801722 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.457G>A; p.E153K; 7:16794957-16794957 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.33C>A; p.L11L; 7:16801764-16801764 |
skin | malignant_melanoma | Substitution - coding silent |
c.331T>C; p.Y111H; 7:16797694-16797694 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.331-1G>T; p.?; 7:16797695-16797695 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Unknown |
c.471A>G; p.T157T; 7:16794943-16794943 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.93G>A; p.K31K; 7:16801704-16801704 |
skin; leg | malignant_melanoma; nodular | Substitution - coding silent |
c.62G>C; p.R21T; 7:16801735-16801735 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.14C>T; p.P5L; 7:16801783-16801783 |
skin | malignant_melanoma | Substitution - Missense |
c.204-1G>T; p.?; 7:16801204-16801204 |
endometrium | carcinoma; endometrioid_carcinoma | Unknown |
c.377C>A; p.P126H; 7:16797648-16797648 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.443G>A; p.R148H; 7:16794971-16794971 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.264G>T; p.K88N; 7:16799810-16799810 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.281A>G; p.N94S; 7:16799793-16799793 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.441T>C; p.N147N; 7:16794973-16794973 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.19T>C; p.S7P; 7:16801778-16801778 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.472G>A; p.A158T; 7:16794942-16794942 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.492G>A; p.M164I; 7:16792944-16792944 |
skin | malignant_melanoma | Substitution - Missense |
c.45C>G; p.L15L; 7:16801752-16801752 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.184C>T; p.L62L; 7:16801339-16801339 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.9A>T; p.K3N; 7:16801788-16801788 |
NS | malignant_melanoma | Substitution - Missense |
c.34C>A; p.L12I; 7:16801763-16801763 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.479-5A>G; p.?; 7:16792962-16792962 |
prostate | carcinoma | Unknown |
c.286G>A; p.E96K; 7:16799788-16799788 |
skin | malignant_melanoma | Substitution - Missense |
c.87C>T; p.A29A; 7:16801710-16801710 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |