Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10381
Symbol

TUBB3

Synonymous

CDCBM|CDCBM1|CFEOM3|CFEOM3A|FEOM3|TUBB4|beta-4

Full name

tubulin, beta 3 class III

Gene description

class III beta-tubulin|tubulin beta-3 chain|tubulin beta-4 chain|tubulin beta-III

Cytoband

16q24.3

Gene type

protein-coding

Synonymous

MIM:602661; HGNC:HGNC:20772; Ensembl:ENSG00000258947; HPRD:04044; Vega:OTTHUMG00000138985

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.487A>G; p.I163V; 16:89934938-89934938

 stomachadenocarcinomaSubstitution - Missense

c.90C>T; p.I30I; 16:89932603-89932603

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1112G>A; p.S371N; 16:89935563-89935563

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.958C>A; p.R320S; 16:89935409-89935409

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1331C>T; p.S444L; 16:89935782-89935782

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.783G>A; p.P261P; 16:89935234-89935234

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.253T>C; p.F85L; 16:89933554-89933554

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.253T>C; p.F85L; 16:89933554-89933554

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1284C>T; p.A428A; 16:89935735-89935735

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1266C>T; p.Y422Y; 16:89935717-89935717

 skinmalignant_melanomaSubstitution - coding silent

c.1116G>A; p.T372T; 16:89935567-89935567

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1261G>A; p.E421K; 16:89935712-89935712

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.763G>A; p.V255I; 16:89935214-89935214

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1064A>C; p.D355A; 16:89935515-89935515

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.637C>T; p.R213C; 16:89935088-89935088

 pancreasNSSubstitution - Missense

c.557C>T; p.T186M; 16:89935008-89935008

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.484C>T; p.R162C; 16:89934935-89934935

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.254T>C; p.F85S; 16:89933555-89933555

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.320C>T; p.T107M; 16:89934771-89934771

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.320C>T; p.T107M; 16:89934771-89934771

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.446C>T; p.T149M; 16:89934897-89934897

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.936G>T; p.T312T; 16:89935387-89935387

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.810C>T; p.F270F; 16:89935261-89935261

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.787C>G; p.L263V; 16:89935238-89935238

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1037C>T; p.P346L; 16:89935488-89935488

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.467G>A; p.R156H; 16:89934918-89934918

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1134C>A; p.F378L; 16:89935585-89935585

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.732C>T; p.G244G; 16:89935183-89935183

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1139G>A; p.R380H; 16:89935590-89935590

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1044C>T; p.N348N; 16:89935495-89935495

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.981C>T; p.D327D; 16:89935432-89935432

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.904G>A; p.A302T; 16:89935355-89935355

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1075C>A; p.R359S; 16:89935526-89935526

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1078G>C; p.G360R; 16:89935529-89935529

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.480C>T; p.P160P; 16:89934931-89934931

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.480C>T; p.P160P; 16:89934931-89934931

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.781C>T; p.P261S; 16:89935232-89935232

 skinmalignant_melanomaSubstitution - Missense

c.1248C>G; p.N416K; 16:89935699-89935699

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.211G>A; p.G71R; 16:89933512-89933512

 pancreascarcinomaSubstitution - Missense

c.211G>A; p.G71R; 16:89933512-89933512

 pancreascarcinomaSubstitution - Missense

c.211G>A; p.G71R; 16:89933512-89933512

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1324G>A; p.E442K; 16:89935775-89935775

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.238G>A; p.A80T; 16:89933539-89933539

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.534G>A; p.T178T; 16:89934985-89934985

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.900G>A; p.M300I; 16:89935351-89935351

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.505G>A; p.V169I; 16:89934956-89934956

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.915G>T; p.P305P; 16:89935366-89935366

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.344C>T; p.S115L; 16:89934795-89934795

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.344C>T; p.S115L; 16:89934795-89934795

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.288G>C; p.G96G; 16:89934739-89934739

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1160C>A; p.A387D; 16:89935611-89935611

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1047G>A; p.V349V; 16:89935498-89935498

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.966C>T; p.S322S; 16:89935417-89935417

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.848C>A; p.A283D; 16:89935299-89935299

 thyroidother; neoplasmSubstitution - Missense

c.966C>T; p.S322S; 16:89935417-89935417

 skinmalignant_melanomaSubstitution - coding silent

c.787C>A; p.L263M; 16:89935238-89935238

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.703G>A; p.G235R; 16:89935154-89935154

 skinmalignant_melanomaSubstitution - Missense

c.613G>A; p.E205K; 16:89935064-89935064

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.703G>A; p.G235R; 16:89935154-89935154

 skinmalignant_melanomaSubstitution - Missense

c.1054G>A; p.A352T; 16:89935505-89935505

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.322G>A; p.E108K; 16:89934773-89934773

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1056C>T; p.A352A; 16:89935507-89935507

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.762C>T; p.A254A; 16:89935213-89935213

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.413C>T; p.S138L; 16:89934864-89934864

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1057G>A; p.V353M; 16:89935508-89935508

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.903C>T; p.A301A; 16:89935354-89935354

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.728C>T; p.P243L; 16:89935179-89935179

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.973G>C; p.E325Q; 16:89935424-89935424

 breastcarcinomaSubstitution - Missense

c.171C>A; p.H57Q; 16:89933472-89933472

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1023C>T; p.F341F; 16:89935474-89935474

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.302G>T; p.W101L; 16:89934753-89934753

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1157C>T; p.T386M; 16:89935608-89935608

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.184C>T; p.R62*; 16:89933485-89933485

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1027G>T; p.E343*; 16:89935478-89935478

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1169G>A; p.R390Q; 16:89935620-89935620

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1036C>T; p.P346S; 16:89935487-89935487

 skinmalignant_melanomaSubstitution - Missense

c.958C>T; p.R320C; 16:89935409-89935409

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.958C>T; p.R320C; 16:89935409-89935409

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1208T>C; p.M403T; 16:89935659-89935659

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1291G>A; p.E431K; 16:89935742-89935742

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1076G>A; p.R359H; 16:89935527-89935527

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.367G>T; p.E123*; 16:89934818-89934818

 skinmalignant_melanomaSubstitution - Nonsense

c.64G>A; p.E22K; 16:89932577-89932577

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.742G>A; p.A248T; 16:89935193-89935193

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1227C>T; p.T409T; 16:89935678-89935678

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1227C>T; p.T409T; 16:89935678-89935678

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.681C>T; p.H227H; 16:89935132-89935132

 skinmalignant_melanomaSubstitution - coding silent

c.362G>A; p.R121Q; 16:89934813-89934813

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1267C>T; p.Q423*; 16:89935718-89935718

 livercarcinomaSubstitution - Nonsense

c.576G>T; p.L192L; 16:89935027-89935027

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.600C>G; p.Y200*; 16:89935051-89935051

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.666C>T; p.Y222Y; 16:89935117-89935117

 pancreascarcinomaSubstitution - coding silent

c.505G>T; p.V169F; 16:89934956-89934956

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.504C>T; p.S168S; 16:89934955-89934955

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1249G>A; p.D417N; 16:89935700-89935700

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.721C>T; p.R241C; 16:89935172-89935172

 breastcarcinomaSubstitution - Missense

c.1293G>T; p.E431D; 16:89935744-89935744

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense