Cancer metastasis database

Annotation category 5

Gene information

Gene ID 1028
Symbol

CDKN1C

Synonymous

BWCR|BWS|KIP2|WBS|p57|p57Kip2

Full name

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

Gene description

cyclin-dependent kinase inhibitor 1C|cyclin-dependent kinase inhibitor p57

Cytoband

11p15.5

Gene type

protein-coding

Synonymous

MIM:600856; HGNC:HGNC:1786; Ensembl:ENSG00000129757; HPRD:02913; Vega:OTTHUMG00000010040

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.776C>A; p.A259D; 11:2884714-2884714

livercarcinomaSubstitution - Missense

c.135_136insT; p.L46fs*79; 11:2885354-2885355

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaInsertion - Frameshift

c.768C>T; p.A256A; 11:2884722-2884722

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.466C>A; p.P156T; 11:2885024-2885024

thyroidother; neoplasmSubstitution - Missense

c.147C>T; p.R49R; 11:2885343-2885343

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.496G>C; p.A166P; 11:2884994-2884994

haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.805G>A; p.G269R; 11:2884685-2884685

livercarcinomaSubstitution - Missense

c.303C>T; p.R101R; 11:2885187-2885187

ovaryother; neoplasmSubstitution - coding silent

c.735G>A; p.G245G; 11:2884755-2884755

skinmalignant_melanomaSubstitution - coding silent

c.262C>T; p.P88S; 11:2885228-2885228

stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.205A>G; p.M69V; 11:2885285-2885285

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.48C>T; p.V16V; 11:2885442-2885442

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.196delC; p.Q66fs*206; 11:2885294-2885294

prostateadenomaDeletion - Frameshift

c.182G>A; p.W61*; 11:2885308-2885308

upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.908G>T; p.G303V; 11:2884047-2884047

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.171C>A; p.D57E; 11:2885319-2885319

thyroidother; neoplasmSubstitution - Missense

c.102C>T; p.F34F; 11:2885388-2885388

skinmalignant_melanomaSubstitution - coding silent