lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	10215
Symbol	OLIG2
Synonymous	BHLHB1\|OLIGO2\|PRKCBP2\|RACK17\|bHLHe19
Full name	oligodendrocyte lineage transcription factor 2
Gene description	basic domain, helix-loop-helix protein, class B, 1\|class B basic helix-loop-helix protein 1\|class E basic helix-loop-helix protein 19\|human protein kinase C-binding protein RACK17\|oligodendrocyte transcription factor 2\|oligodendrocyte-specific bHLH transc
Cytoband	21q22.11
Gene type	protein-coding
Synonymous	MIM:606386; HGNC:HGNC:9398; Ensembl:ENSG00000205927; HPRD:07334; Vega:OTTHUMG00000065032

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.617C>T; p.A206V; 21:33027479-33027479	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.328C>T; p.R110C; 21:33027190-33027190	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.111C>T; p.G37G; 21:33026973-33026973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.572G>A; p.G191D; 21:33027434-33027434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.77G>T; p.S26I; 21:33026939-33026939	pancreas	carcinoma	Substitution - Missense
c.95G>T; p.S32I; 21:33026957-33026957	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.172G>A; p.A58T; 21:33027034-33027034	meninges	meningioma	Substitution - Missense
c.237G>A; p.S79S; 21:33027099-33027099	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.237G>A; p.S79S; 21:33027099-33027099	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.427G>A; p.V143M; 21:33027289-33027289	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.540C>A; p.H180Q; 21:33027402-33027402	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.427G>A; p.V143M; 21:33027289-33027289	urinary_tract; bladder	carcinoma	Substitution - Missense
c.588G>A; p.A196A; 21:33027450-33027450	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.166C>T; p.R56C; 21:33027028-33027028	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.594G>T; p.L198L; 21:33027456-33027456	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.231A>G; p.S77S; 21:33027093-33027093	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.763C>G; p.R255G; 21:33027625-33027625	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.24G>T; p.V8V; 21:33026886-33026886	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.608C>T; p.A203V; 21:33027470-33027470	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.267G>C; p.A89A; 21:33027129-33027129	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.425C>T; p.S142L; 21:33027287-33027287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>T; p.A53V; 21:33027020-33027020	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>T; p.A53V; 21:33027020-33027020	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>T; p.A53V; 21:33027020-33027020	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>T; p.A53V; 21:33027020-33027020	large_intestine; colon	carcinoma	Substitution - Missense
c.158C>T; p.A53V; 21:33027020-33027020	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.74G>A; p.R25Q; 21:33026936-33026936	skin	malignant_melanoma	Substitution - Missense
c.379G>A; p.A127T; 21:33027241-33027241	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.221G>A; p.G74D; 21:33027083-33027083	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.144G>A; p.P48P; 21:33027006-33027006	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.925G>T; p.A309S; 21:33027787-33027787	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.925G>T; p.A309S; 21:33027787-33027787	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.925G>T; p.A309S; 21:33027787-33027787	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.925G>T; p.A309S; 21:33027787-33027787	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.925G>T; p.A309S; 21:33027787-33027787	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.362T>A; p.M121K; 21:33027224-33027224	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.362T>A; p.M121K; 21:33027224-33027224	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.563C>T; p.A188V; 21:33027425-33027425	ovary	other; neoplasm	Substitution - Missense
c.633C>T; p.A211A; 21:33027495-33027495	pancreas	carcinoma	Substitution - coding silent
c.156C>T; p.S52S; 21:33027018-33027018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.209T>C; p.L70P; 21:33027071-33027071	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.262T>G; p.S88A; 21:33027124-33027124	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.262T>G; p.S88A; 21:33027124-33027124	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.298_299insAGC; p.Q100_M101insQ; 21:33027160-33027161	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Insertion - In frame
c.262T>G; p.S88A; 21:33027124-33027124	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.298_299insAGC; p.Q100_M101insQ; 21:33027160-33027161	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Insertion - In frame
c.8C>T; p.S3L; 21:33026870-33026870	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>A; p.A53T; 21:33027019-33027019	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>A; p.A53T; 21:33027019-33027019	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.617C>G; p.A206G; 21:33027479-33027479	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.447C>T; p.I149I; 21:33027309-33027309	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.396C>T; p.R132R; 21:33027258-33027258	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.266C>T; p.A89V; 21:33027128-33027128	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation