lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	10163
Symbol	WASF2
Synonymous	IMD2\|SCAR2\|WASF4\|WAVE2\|dJ393P12.2
Full name	WAS protein family, member 2
Gene description	WASP family Verprolin-homologous protein 2\|WASP family protein member 2\|WASP family protein member 4\|protein WAVE-2\|putative Wiskott-Aldrich syndrome protein family member 4\|suppressor of cyclic-AMP receptor (WASP-family)\|verprolin homology domain-contain
Cytoband	1p36.11
Gene type	protein-coding
Synonymous	MIM:605875; HGNC:HGNC:12733; Ensembl:ENSG00000158195; HPRD:05796; Vega:OTTHUMG00000003393

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.581G>A; p.R194H; 1:27414920-27414920	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.81C>T; p.C27C; 1:27428810-27428810	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.81C>T; p.C27C; 1:27428810-27428810	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.81C>T; p.C27C; 1:27428810-27428810	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.185C>G; p.A62G; 1:27419034-27419034	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.604G>C; p.E202Q; 1:27414897-27414897	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.871A>G; p.R291G; 1:27410160-27410160	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6G>A; p.P2P; 1:27428885-27428885	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.788C>T; p.S263F; 1:27412608-27412608	skin	malignant_melanoma	Substitution - Missense
c.169C>G; p.Q57E; 1:27419050-27419050	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.198C>A; p.S66R; 1:27419021-27419021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.760T>A; p.S254T; 1:27412636-27412636	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.894C>T; p.S298S; 1:27410137-27410137	skin	malignant_melanoma	Substitution - coding silent
c.1188T>C; p.P396P; 1:27409843-27409843	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1052C>T; p.S351L; 1:27409979-27409979	urinary_tract; bladder	carcinoma	Substitution - Missense
c.172G>A; p.A58T; 1:27419047-27419047	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.361T>C; p.L121L; 1:27418327-27418327	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.43C>G; p.R15G; 1:27428848-27428848	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.904C>A; p.P302T; 1:27410127-27410127	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.423C>T; p.D141D; 1:27416099-27416099	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.15G>A; p.T5T; 1:27428876-27428876	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.217G>A; p.D73N; 1:27419002-27419002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.550G>A; p.D184N; 1:27414951-27414951	pancreas	carcinoma	Substitution - Missense
c.273G>A; p.L91L; 1:27418415-27418415	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.171G>T; p.Q57H; 1:27419048-27419048	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.596G>A; p.R199H; 1:27414905-27414905	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1211C>T; p.P404L; 1:27409820-27409820	skin	malignant_melanoma	Substitution - Missense
c.142G>A; p.E48K; 1:27419077-27419077	urinary_tract; bladder	carcinoma	Substitution - Missense
c.516G>A; p.M172I; 1:27416006-27416006	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.356C>T; p.P119L; 1:27418332-27418332	skin	malignant_melanoma	Substitution - Missense
c.1005A>G; p.P335P; 1:27410026-27410026	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.782C>T; p.S261F; 1:27412614-27412614	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.316C>T; p.Q106*; 1:27418372-27418372	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.531G>A; p.K177K; 1:27415991-27415991	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.388C>T; p.P130S; 1:27418300-27418300	urinary_tract; bladder	carcinoma	Substitution - Missense
c.15G>T; p.T5T; 1:27428876-27428876	salivary_gland	carcinoma; adenoid_cystic_carcinoma	Substitution - coding silent
c.298T>A; p.F100I; 1:27418390-27418390	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1182C>T; p.P394P; 1:27409849-27409849	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.112C>T; p.R38*; 1:27428779-27428779	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1084G>T; p.A362S; 1:27409947-27409947	skin	malignant_melanoma	Substitution - Missense
c.443A>C; p.K148T; 1:27416079-27416079	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1074C>T; p.H358H; 1:27409957-27409957	skin	malignant_melanoma	Substitution - coding silent
c.552T>C; p.D184D; 1:27414949-27414949	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1332C>T; p.I444I; 1:27409699-27409699	skin	malignant_melanoma	Substitution - coding silent
c.478T>C; p.W160R; 1:27416044-27416044	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.358G>C; p.V120L; 1:27418330-27418330	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.892A>G; p.S298G; 1:27410139-27410139	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.711T>C; p.C237C; 1:27412685-27412685	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.156A>G; p.G52G; 1:27419063-27419063	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.698G>A; p.G233D; 1:27412698-27412698	skin	malignant_melanoma	Substitution - Missense
c.406C>G; p.L136V; 1:27418282-27418282	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.803C>A; p.P268H; 1:27412593-27412593	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1302C>T; p.S434S; 1:27409729-27409729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.889_890CC>TT; p.P297L; 1:27410141-27410142	skin	malignant_melanoma	Substitution - Missense
c.439C>T; p.L147F; 1:27416083-27416083	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.741G>A; p.P247P; 1:27412655-27412655	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.324G>T; p.Q108H; 1:27418364-27418364	breast	carcinoma	Substitution - Missense
c.802C>G; p.P268A; 1:27412594-27412594	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.804T>C; p.P268P; 1:27412592-27412592	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.208G>C; p.E70Q; 1:27419011-27419011	breast	carcinoma	Substitution - Missense
c.804T>C; p.P268P; 1:27412592-27412592	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.320A>G; p.D107G; 1:27418368-27418368	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.786C>G; p.F262L; 1:27412610-27412610	breast	carcinoma	Substitution - Missense
c.208G>A; p.E70K; 1:27419011-27419011	urinary_tract; bladder	carcinoma	Substitution - Missense
c.830C>T; p.P277L; 1:27410201-27410201	skin	malignant_melanoma	Substitution - Missense
c.208G>A; p.E70K; 1:27419011-27419011	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.737A>G; p.Y246C; 1:27412659-27412659	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.835G>A; p.D279N; 1:27410196-27410196	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.942C>G; p.P314P; 1:27410089-27410089	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.541G>T; p.E181*; 1:27414960-27414960	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.584A>C; p.K195T; 1:27414917-27414917	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.541G>T; p.E181*; 1:27414960-27414960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.263A>G; p.E88G; 1:27418956-27418956	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.135A>C; p.K45N; 1:27419084-27419084	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.449A>G; p.Y150C; 1:27416073-27416073	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation