lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1010
Symbol	CDH12
Synonymous	CDHB
Full name	cadherin 12, type 2 (N-cadherin 2)
Gene description	Br-cadherin\|N-cadherin 2\|brain cadherin\|brain-cadherin\|cadherin, neural type, 2\|cadherin-12\|neural type cadherin 2\|neuronal cadherin 2
Cytoband	5p14.3
Gene type	protein-coding
Synonymous	MIM:600562; HGNC:HGNC:1751; Ensembl:ENSG00000154162; HPRD:11081; Vega:OTTHUMG00000090591

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.299C>G; p.T100S; 5:21975318-21975318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.541C>T; p.Q181*; 5:21854776-21854776	skin	malignant_melanoma	Substitution - Nonsense
c.202G>A; p.V68M; 5:22078475-22078475	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1509A>T; p.P503P; 5:21764984-21764984	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.666G>T; p.L222F; 5:21842309-21842309	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1196T>A; p.V399E; 5:21802227-21802227	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1493G>T; p.C498F; 5:21765000-21765000	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2200G>A; p.D734N; 5:21751922-21751922	skin	malignant_melanoma	Substitution - Missense
c.569C>A; p.P190Q; 5:21854748-21854748	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2155C>T; p.Q719*; 5:21751967-21751967	breast	carcinoma	Substitution - Nonsense
c.499G>T; p.A167S; 5:21975118-21975118	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.483G>A; p.L161L; 5:21975134-21975134	skin	malignant_melanoma	Substitution - coding silent
c.286G>C; p.D96H; 5:21975331-21975331	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.192G>A; p.L64L; 5:22078485-22078485	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.292G>A; p.A98T; 5:21975325-21975325	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.731G>T; p.G244V; 5:21842244-21842244	stomach	adenocarcinoma	Substitution - Missense
c.1382C>A; p.A461E; 5:21783369-21783369	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1344C>A; p.D448E; 5:21783407-21783407	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.577G>A; p.G193R; 5:21854740-21854740	skin	malignant_melanoma	Substitution - Missense
c.2141G>T; p.R714M; 5:21751981-21751981	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2047G>T; p.V683L; 5:21752075-21752075	breast	carcinoma	Substitution - Missense
c.1963G>C; p.D655H; 5:21752159-21752159	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1968C>A; p.N656K; 5:21752154-21752154	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.554C>G; p.T185R; 5:21854763-21854763	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2175T>C; p.D725D; 5:21751947-21751947	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1762C>T; p.R588*; 5:21755714-21755714	breast	carcinoma	Substitution - Nonsense
c.2175T>C; p.D725D; 5:21751947-21751947	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.451C>A; p.Q151K; 5:21975166-21975166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1918C>A; p.Q640K; 5:21752204-21752204	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1312G>A; p.E438K; 5:21783439-21783439	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2259T>G; p.S753S; 5:21751863-21751863	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069C>A; p.H357N; 5:21802354-21802354	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1155C>A; p.S385R; 5:21802268-21802268	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1918C>A; p.Q640K; 5:21752204-21752204	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>T; p.G87G; 5:21975356-21975356	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1371C>A; p.F457L; 5:21783380-21783380	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1371C>A; p.F457L; 5:21783380-21783380	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.789T>C; p.N263N; 5:21842186-21842186	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1645G>A; p.G549R; 5:21755831-21755831	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.637C>A; p.P213T; 5:21854680-21854680	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.103C>T; p.P35S; 5:22078574-22078574	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1436T>C; p.V479A; 5:21765057-21765057	lung	carcinoid-endocrine_tumour; atypical	Substitution - Missense
c.2028G>T; p.G676G; 5:21752094-21752094	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.57C>T; p.L19L; 5:22078620-22078620	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1904T>A; p.V635E; 5:21752218-21752218	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2110A>G; p.R704G; 5:21752012-21752012	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.231+9G>A; p.?; 5:22078437-22078437	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Unknown
c.2131A>C; p.T711P; 5:21751991-21751991	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2131A>C; p.T711P; 5:21751991-21751991	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1307G>A; p.G436E; 5:21783444-21783444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1306G>A; p.G436R; 5:21783445-21783445	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1456C>T; p.P486S; 5:21765037-21765037	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1767C>A; p.V589V; 5:21755709-21755709	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2296G>T; p.D766Y; 5:21751826-21751826	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.743G>A; p.G248E; 5:21842232-21842232	thyroid	carcinoma	Substitution - Missense
c.2319C>A; p.P773P; 5:21751803-21751803	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1413C>A; p.S471R; 5:21765080-21765080	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2082A>T; p.K694N; 5:21752040-21752040	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1213G>A; p.A405T; 5:21802210-21802210	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1023G>C; p.K341N; 5:21802400-21802400	breast	carcinoma	Substitution - Missense
c.25C>A; p.L9M; 5:22078652-22078652	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.691G>T; p.E231*; 5:21842284-21842284	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.224T>C; p.V75A; 5:22078453-22078453	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.643A>T; p.T215S; 5:21854674-21854674	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1559C>T; p.A520V; 5:21760632-21760632	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1061A>G; p.H354R; 5:21802362-21802362	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2283C>T; p.A761A; 5:21751839-21751839	pancreas	carcinoma	Substitution - coding silent
c.2025C>G; p.I675M; 5:21752097-21752097	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.Q245*; 5:21842242-21842242	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.103C>A; p.P35T; 5:22078574-22078574	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.382C>T; p.R128C; 5:21975235-21975235	stomach	adenocarcinoma	Substitution - Missense
c.679A>C; p.R227R; 5:21842296-21842296	pancreas	carcinoma	Substitution - coding silent
c.1001A>G; p.K334R; 5:21816946-21816946	thyroid	carcinoma	Substitution - Missense
c.679A>C; p.R227R; 5:21842296-21842296	pancreas	carcinoma	Substitution - coding silent
c.1910T>C; p.L637P; 5:21752212-21752212	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2122G>A; p.E708K; 5:21752000-21752000	skin	malignant_melanoma	Substitution - Missense
c.152G>A; p.R51H; 5:22078525-22078525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.540C>A; p.L180L; 5:21854777-21854777	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1911G>A; p.L637L; 5:21752211-21752211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2292C>A; p.D764E; 5:21751830-21751830	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1747A>T; p.N583Y; 5:21755729-21755729	skin	malignant_melanoma	Substitution - Missense
c.1267G>T; p.D423Y; 5:21783484-21783484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.204G>C; p.V68V; 5:22078473-22078473	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1270T>A; p.W424R; 5:21783481-21783481	prostate	carcinoma	Substitution - Missense
c.267G>A; p.V89V; 5:21975350-21975350	skin	malignant_melanoma	Substitution - coding silent
c.23C>T; p.S8F; 5:22078654-22078654	skin	malignant_melanoma	Substitution - Missense
c.1518A>G; p.I506M; 5:21760673-21760673	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.136C>T; p.R46W; 5:22078541-22078541	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.23C>T; p.S8F; 5:22078654-22078654	skin	malignant_melanoma	Substitution - Missense
c.23C>T; p.S8F; 5:22078654-22078654	skin	malignant_melanoma	Substitution - Missense
c.136C>T; p.R46W; 5:22078541-22078541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.37delG; p.V13fs*8; 5:22078640-22078640	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2224G>T; p.E742*; 5:21751898-21751898	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.127C>T; p.P43S; 5:22078550-22078550	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.438C>G; p.F146L; 5:21975179-21975179	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.477G>A; p.K159K; 5:21975140-21975140	ovary	other; neoplasm	Substitution - coding silent
c.866G>A; p.G289E; 5:21817081-21817081	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.11G>A; p.R4K; 5:22078666-22078666	skin	malignant_melanoma	Substitution - Missense
c.1735C>T; p.Q579*; 5:21755741-21755741	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1893T>G; p.V631V; 5:21752229-21752229	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.562G>A; p.D188N; 5:21854755-21854755	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.275C>A; p.T92N; 5:21975342-21975342	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2045A>C; p.K682T; 5:21752077-21752077	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1794C>T; p.I598I; 5:21755682-21755682	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1701C>T; p.L567L; 5:21755775-21755775	skin	malignant_melanoma	Substitution - coding silent
c.487G>T; p.G163*; 5:21975130-21975130	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1382C>T; p.A461V; 5:21783369-21783369	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1382C>T; p.A461V; 5:21783369-21783369	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.585T>C; p.S195S; 5:21854732-21854732	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.525G>T; p.V175V; 5:21975092-21975092	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1823T>C; p.L608P; 5:21755653-21755653	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.893T>G; p.F298C; 5:21817054-21817054	central_nervous_system; brain	glioma	Substitution - Missense
c.301G>A; p.V101I; 5:21975316-21975316	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1823T>C; p.L608P; 5:21755653-21755653	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.982G>A; p.G328R; 5:21816965-21816965	skin	malignant_melanoma	Substitution - Missense
c.249C>G; p.D83E; 5:21975368-21975368	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1389A>C; p.K463N; 5:21783362-21783362	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2065A>G; p.I689V; 5:21752057-21752057	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1575C>T; p.S525S; 5:21760616-21760616	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.43T>C; p.F15L; 5:22078634-22078634	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.540C>T; p.L180L; 5:21854777-21854777	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1721G>A; p.S574N; 5:21755755-21755755	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1721G>A; p.S574N; 5:21755755-21755755	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1354A>C; p.T452P; 5:21783397-21783397	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.802C>T; p.R268*; 5:21842173-21842173	skin	malignant_melanoma	Substitution - Nonsense
c.802C>T; p.R268*; 5:21842173-21842173	skin	malignant_melanoma	Substitution - Nonsense
c.1514A>T; p.Q505L; 5:21764979-21764979	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2204C>T; p.S735L; 5:21751918-21751918	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1912C>T; p.R638*; 5:21752210-21752210	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1463A>G; p.E488G; 5:21765030-21765030	liver	carcinoma	Substitution - Missense
c.2263G>T; p.D755Y; 5:21751859-21751859	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302T>C; p.V101A; 5:21975315-21975315	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.565G>T; p.D189Y; 5:21854752-21854752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1450G>T; p.E484*; 5:21765043-21765043	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.465T>A; p.D155E; 5:21975152-21975152	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1954G>A; p.D652N; 5:21752168-21752168	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1571T>A; p.F524Y; 5:21760620-21760620	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.763G>T; p.V255F; 5:21842212-21842212	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>C; p.V132L; 5:21975223-21975223	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2030C>T; p.A677V; 5:21752092-21752092	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1271_1272GG>TT; p.W424>?; 5:21783479-21783480	lung	carcinoma; adenocarcinoma	Complex
c.1224T>C; p.A408A; 5:21802199-21802199	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.964G>A; p.D322N; 5:21816983-21816983	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.682G>T; p.E228*; 5:21842293-21842293	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2083C>T; p.P695S; 5:21752039-21752039	skin	malignant_melanoma	Substitution - Missense
c.1257-7T>G; p.?; 5:21783501-21783501	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Unknown
c.996G>C; p.L332F; 5:21816951-21816951	breast	carcinoma	Substitution - Missense
c.2181T>C; p.D727D; 5:21751941-21751941	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.40C>A; p.L14M; 5:22078637-22078637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.526G>A; p.G176S; 5:21975091-21975091	breast	carcinoma	Substitution - Missense
c.2321G>A; p.R774H; 5:21751801-21751801	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2064A>C; p.K688N; 5:21752058-21752058	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2074G>A; p.D692N; 5:21752048-21752048	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2148C>T; p.F716F; 5:21751974-21751974	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1567C>A; p.Q523K; 5:21760624-21760624	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.401T>C; p.I134T; 5:21975216-21975216	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.356G>A; p.R119K; 5:21975261-21975261	skin	malignant_melanoma	Substitution - Missense
c.916T>C; p.Y306H; 5:21817031-21817031	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.647-2A>T; p.?; 5:21842330-21842330	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.325G>A; p.G109R; 5:21975292-21975292	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812A>T; p.K271I; 5:21842163-21842163	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.166T>C; p.W56R; 5:22078511-22078511	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1495G>A; p.E499K; 5:21764998-21764998	skin	malignant_melanoma	Substitution - Missense
c.790G>T; p.D264Y; 5:21842185-21842185	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.254G>A; p.G85E; 5:21975363-21975363	skin	malignant_melanoma	Substitution - Missense
c.693A>G; p.E231E; 5:21842282-21842282	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2079A>C; p.I693I; 5:21752043-21752043	ovary	other; neoplasm	Substitution - coding silent
c.427G>T; p.E143*; 5:21975190-21975190	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.803G>A; p.R268Q; 5:21842172-21842172	skin	malignant_melanoma	Substitution - Missense
c.2176G>T; p.V726L; 5:21751946-21751946	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.940G>C; p.G314R; 5:21817007-21817007	bone; femur	chondrosarcoma	Substitution - Missense
c.40C>T; p.L14L; 5:22078637-22078637	skin	malignant_melanoma	Substitution - coding silent
c.815-3C>T; p.?; 5:21817135-21817135	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.1604A>C; p.K535T; 5:21760587-21760587	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.749C>G; p.A250G; 5:21842226-21842226	liver	carcinoma	Substitution - Missense
c.749C>G; p.A250G; 5:21842226-21842226	liver	carcinoma	Substitution - Missense
c.2314G>A; p.G772R; 5:21751808-21751808	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1910T>A; p.L637Q; 5:21752212-21752212	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1307G>T; p.G436V; 5:21783444-21783444	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.159A>C; p.K53N; 5:22078518-22078518	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.42G>T; p.L14L; 5:22078635-22078635	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2311T>C; p.W771R; 5:21751811-21751811	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.857C>T; p.S286L; 5:21817090-21817090	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.1216G>C; p.V406L; 5:21802207-21802207	pancreas	carcinoma	Substitution - Missense
c.1602C>T; p.I534I; 5:21760589-21760589	skin	malignant_melanoma	Substitution - coding silent
c.613G>A; p.G205R; 5:21854704-21854704	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.396_397GG>TT; p.V132>?; 5:21975220-21975221	lung	carcinoma; small_cell_carcinoma	Complex
c.1132G>A; p.V378I; 5:21802291-21802291	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.613G>A; p.G205R; 5:21854704-21854704	skin	malignant_melanoma	Substitution - Missense
c.59T>C; p.L20P; 5:22078618-22078618	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1675C>T; p.R559C; 5:21755801-21755801	liver	carcinoma	Substitution - Missense
c.1282G>A; p.G428R; 5:21783469-21783469	skin	malignant_melanoma	Substitution - Missense
c.1675C>T; p.R559C; 5:21755801-21755801	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1810G>T; p.E604*; 5:21755666-21755666	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1763G>C; p.R588P; 5:21755713-21755713	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1023G>T; p.K341N; 5:21802400-21802400	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2068C>T; p.R690C; 5:21752054-21752054	skin	malignant_melanoma	Substitution - Missense
c.1658G>A; p.R553Q; 5:21755818-21755818	skin	malignant_melanoma	Substitution - Missense
c.568C>A; p.P190T; 5:21854749-21854749	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.230A>C; p.K77T; 5:22078447-22078447	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2286C>A; p.D762E; 5:21751836-21751836	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2005G>C; p.D669H; 5:21752117-21752117	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.568C>A; p.P190T; 5:21854749-21854749	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.368C>T; p.P123L; 5:21975249-21975249	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1549C>A; p.L517I; 5:21760642-21760642	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.178C>G; p.Q60E; 5:22078499-22078499	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.368C>T; p.P123L; 5:21975249-21975249	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2199C>T; p.Y733Y; 5:21751923-21751923	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1489G>A; p.V497M; 5:21765004-21765004	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.87G>T; p.Q29H; 5:22078590-22078590	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.301G>T; p.V101F; 5:21975316-21975316	urinary_tract; bladder	carcinoma	Substitution - Missense
c.138G>T; p.R46R; 5:22078539-22078539	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1971C>T; p.V657V; 5:21752151-21752151	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.974C>T; p.T325I; 5:21816973-21816973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1954G>T; p.D652Y; 5:21752168-21752168	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1757C>T; p.T586I; 5:21755719-21755719	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.281C>G; p.S94*; 5:21975336-21975336	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.721G>A; p.D241N; 5:21842254-21842254	skin	malignant_melanoma	Substitution - Missense
c.802C>A; p.R268R; 5:21842173-21842173	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.1159C>G; p.P387A; 5:21802264-21802264	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.497T>C; p.V166A; 5:21975120-21975120	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2231G>A; p.S744N; 5:21751891-21751891	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1041A>C; p.K347N; 5:21802382-21802382	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1604A>T; p.K535I; 5:21760587-21760587	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.64C>G; p.P22A; 5:22078613-22078613	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.64C>G; p.P22A; 5:22078613-22078613	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.941G>A; p.G314E; 5:21817006-21817006	breast	carcinoma	Substitution - Missense
c.438C>T; p.F146F; 5:21975179-21975179	skin	malignant_melanoma	Substitution - coding silent
c.195A>G; p.E65E; 5:22078482-22078482	skin	malignant_melanoma	Substitution - coding silent
c.465T>C; p.D155D; 5:21975152-21975152	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1676G>A; p.R559H; 5:21755800-21755800	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.621T>A; p.P207P; 5:21854696-21854696	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.465T>C; p.D155D; 5:21975152-21975152	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1676G>A; p.R559H; 5:21755800-21755800	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.621T>A; p.P207P; 5:21854696-21854696	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1122C>A; p.S374R; 5:21802301-21802301	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.907G>T; p.E303*; 5:21817040-21817040	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1447A>C; p.N483H; 5:21765046-21765046	breast	carcinoma	Substitution - Missense
c.2015C>T; p.A672V; 5:21752107-21752107	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.458T>A; p.I153N; 5:21975159-21975159	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.907G>T; p.E303*; 5:21817040-21817040	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.814+1G>A; p.?; 5:21842160-21842160	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1786G>A; p.G596S; 5:21755690-21755690	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.375C>A; p.Y125*; 5:21975242-21975242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1624_1625GA>TT; p.D542>?; 5:21760566-21760567	lung	carcinoma; adenocarcinoma	Complex
c.1390G>A; p.V464I; 5:21783361-21783361	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1390G>A; p.V464I; 5:21783361-21783361	NS	malignant_melanoma	Substitution - Missense
c.1000A>G; p.K334E; 5:21816947-21816947	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.291C>T; p.G97G; 5:21975326-21975326	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.869G>T; p.R290I; 5:21817078-21817078	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.667C>A; p.P223T; 5:21842308-21842308	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.520C>G; p.P174A; 5:21975097-21975097	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1203C>A; p.T401T; 5:21802220-21802220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.130G>C; p.G44R; 5:22078547-22078547	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2349C>T; p.G783G; 5:21751773-21751773	pancreas	carcinoma	Substitution - coding silent
c.1963G>A; p.D655N; 5:21752159-21752159	skin	malignant_melanoma	Substitution - Missense
c.2349C>T; p.G783G; 5:21751773-21751773	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1085C>T; p.A362V; 5:21802338-21802338	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2352A>C; p.E784D; 5:21751770-21751770	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2352A>C; p.E784D; 5:21751770-21751770	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.680G>A; p.R227K; 5:21842295-21842295	breast	carcinoma	Substitution - Missense
c.2313G>T; p.W771C; 5:21751809-21751809	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1815A>G; p.A605A; 5:21755661-21755661	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.284G>T; p.G95V; 5:21975333-21975333	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1152C>T; p.F384F; 5:21802271-21802271	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2020G>A; p.D674N; 5:21752102-21752102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2020G>A; p.D674N; 5:21752102-21752102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1705G>A; p.V569I; 5:21755771-21755771	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2020G>A; p.D674N; 5:21752102-21752102	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.616C>A; p.Q206K; 5:21854701-21854701	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1766T>C; p.V589A; 5:21755710-21755710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2173G>A; p.D725N; 5:21751949-21751949	skin	malignant_melanoma	Substitution - Missense
c.473C>T; p.P158L; 5:21975144-21975144	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1879C>T; p.L627F; 5:21755597-21755597	skin	malignant_melanoma	Substitution - Missense
c.1505A>C; p.K502T; 5:21764988-21764988	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.180_181insC; p.F61fs*45; 5:22078496-22078497	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1879C>T; p.L627F; 5:21755597-21755597	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1274A>T; p.K425M; 5:21783477-21783477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1396A>G; p.N466D; 5:21765097-21765097	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1233G>A; p.L411L; 5:21802190-21802190	pancreas	carcinoma	Substitution - coding silent
c.272delA; p.Y91fs*24; 5:21975345-21975345	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.49G>T; p.G17*; 5:22078628-22078628	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1984G>T; p.D662Y; 5:21752138-21752138	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1131C>T; p.D377D; 5:21802292-21802292	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2353G>T; p.E785*; 5:21751769-21751769	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2280A>C; p.E760D; 5:21751842-21751842	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1917G>T; p.R639S; 5:21752205-21752205	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.703G>T; p.V235L; 5:21842272-21842272	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1091C>T; p.P364L; 5:21802332-21802332	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2239G>A; p.V747M; 5:21751883-21751883	breast	carcinoma	Substitution - Missense
c.1835T>C; p.L612P; 5:21755641-21755641	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1496A>G; p.E499G; 5:21764997-21764997	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1980C>T; p.Y660Y; 5:21752142-21752142	prostate	carcinoma	Substitution - coding silent
c.299C>T; p.T100I; 5:21975318-21975318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.516G>T; p.M172I; 5:21975101-21975101	breast	carcinoma	Substitution - Missense
c.186_187insT; p.V63fs*43; 5:22078490-22078491	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1832G>A; p.G611E; 5:21755644-21755644	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.372C>A; p.F124L; 5:21975245-21975245	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.321C>A; p.T107T; 5:21975296-21975296	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1832G>A; p.G611E; 5:21755644-21755644	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.569_570insC; p.T191fs*22; 5:21854747-21854748	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1988A>G; p.E663G; 5:21752134-21752134	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1161G>A; p.P387P; 5:21802262-21802262	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1832G>A; p.G611E; 5:21755644-21755644	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1161G>A; p.P387P; 5:21802262-21802262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1161G>A; p.P387P; 5:21802262-21802262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1359G>A; p.A453A; 5:21783392-21783392	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1359G>A; p.A453A; 5:21783392-21783392	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1861C>A; p.L621I; 5:21755615-21755615	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1359G>A; p.A453A; 5:21783392-21783392	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1258T>C; p.Y420H; 5:21783493-21783493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2069G>A; p.R690H; 5:21752053-21752053	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.12G>A; p.R4R; 5:22078665-22078665	ovary	other; neoplasm	Substitution - coding silent
c.2069G>A; p.R690H; 5:21752053-21752053	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.163G>T; p.G55C; 5:22078514-22078514	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1973T>C; p.I658T; 5:21752149-21752149	pancreas	carcinoma	Substitution - Missense
c.219G>T; p.Q73H; 5:22078458-22078458	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2224G>A; p.E742K; 5:21751898-21751898	skin	malignant_melanoma	Substitution - Missense
c.1222G>T; p.A408S; 5:21802201-21802201	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1379T>C; p.I460T; 5:21783372-21783372	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2224G>A; p.E742K; 5:21751898-21751898	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1400C>T; p.P467L; 5:21765093-21765093	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1057C>T; p.L353F; 5:21802366-21802366	skin	malignant_melanoma	Substitution - Missense
c.2224G>A; p.E742K; 5:21751898-21751898	skin; scalp	malignant_melanoma	Substitution - Missense
c.2224G>A; p.E742K; 5:21751898-21751898	skin	malignant_melanoma	Substitution - Missense
c.586G>C; p.A196P; 5:21854731-21854731	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.64C>A; p.P22T; 5:22078613-22078613	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.595G>A; p.V199I; 5:21854722-21854722	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1320C>T; p.T440T; 5:21783431-21783431	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.646G>A; p.G216S; 5:21854671-21854671	skin	malignant_melanoma	Substitution - Missense
c.646G>A; p.G216S; 5:21854671-21854671	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1844G>T; p.G615V; 5:21755632-21755632	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1544G>A; p.R515Q; 5:21760647-21760647	skin	malignant_melanoma	Substitution - Missense
c.2226A>T; p.E742D; 5:21751896-21751896	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1544G>A; p.R515Q; 5:21760647-21760647	skin	malignant_melanoma	Substitution - Missense
c.1569A>G; p.Q523Q; 5:21760622-21760622	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1544G>A; p.R515Q; 5:21760647-21760647	skin	malignant_melanoma	Substitution - Missense
c.2230A>T; p.S744C; 5:21751892-21751892	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1902T>C; p.Y634Y; 5:21752220-21752220	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1170C>G; p.T390T; 5:21802253-21802253	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1192C>T; p.P398S; 5:21802231-21802231	skin	malignant_melanoma	Substitution - Missense
c.143A>C; p.H48P; 5:22078534-22078534	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1190C>G; p.T397S; 5:21802233-21802233	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1393A>T; p.S465C; 5:21783358-21783358	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1572C>A; p.F524L; 5:21760619-21760619	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.374A>T; p.Y125F; 5:21975243-21975243	pancreas	carcinoma	Substitution - Missense
c.89C>G; p.T30S; 5:22078588-22078588	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2242G>A; p.A748T; 5:21751880-21751880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.109G>A; p.E37K; 5:22078568-22078568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.409A>G; p.R137G; 5:21975208-21975208	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.955A>C; p.I319L; 5:21816992-21816992	central_nervous_system; brain	glioma	Substitution - Missense
c.1358C>T; p.A453V; 5:21783393-21783393	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.53G>A; p.G18D; 5:22078624-22078624	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1913G>A; p.R638Q; 5:21752209-21752209	pancreas	carcinoma	Substitution - Missense
c.1607C>A; p.P536Q; 5:21760584-21760584	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1358C>T; p.A453V; 5:21783393-21783393	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1913G>A; p.R638Q; 5:21752209-21752209	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1169C>A; p.T390N; 5:21802254-21802254	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1530C>A; p.V510V; 5:21760661-21760661	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.751G>A; p.G251R; 5:21842224-21842224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.751G>A; p.G251R; 5:21842224-21842224	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.832G>T; p.V278F; 5:21817115-21817115	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2136C>T; p.D712D; 5:21751986-21751986	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1516A>G; p.I506V; 5:21760675-21760675	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1180T>G; p.Y394D; 5:21802243-21802243	pancreas	carcinoma	Substitution - Missense
c.2238C>T; p.S746S; 5:21751884-21751884	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2238C>T; p.S746S; 5:21751884-21751884	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2152C>A; p.H718N; 5:21751970-21751970	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1285G>A; p.D429N; 5:21783466-21783466	skin	malignant_melanoma	Substitution - Missense
c.1285G>A; p.D429N; 5:21783466-21783466	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.222T>A; p.Y74*; 5:22078455-22078455	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1440A>C; p.L480F; 5:21765053-21765053	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.2341A>T; p.M781L; 5:21751781-21751781	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2014G>C; p.A672P; 5:21752108-21752108	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1435G>A; p.V479I; 5:21765058-21765058	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.326G>T; p.G109V; 5:21975291-21975291	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.390G>T; p.Q130H; 5:21975227-21975227	ovary	other; neoplasm	Substitution - Missense
c.1759delA; p.I587fs*24; 5:21755717-21755717	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.810C>G; p.P270P; 5:21842165-21842165	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1963G>T; p.D655Y; 5:21752159-21752159	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2358G>A; p.E786E; 5:21751764-21751764	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.569C>T; p.P190L; 5:21854748-21854748	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.441C>A; p.I147I; 5:21975176-21975176	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.269A>G; p.K90R; 5:21975348-21975348	central_nervous_system; brain	glioma	Substitution - Missense
c.259G>T; p.G87C; 5:21975358-21975358	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.603C>T; p.S201S; 5:21854714-21854714	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.957C>T; p.I319I; 5:21816990-21816990	breast	carcinoma	Substitution - coding silent
c.160C>T; p.R54C; 5:22078517-22078517	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1212C>T; p.G404G; 5:21802211-21802211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.256G>A; p.E86K; 5:21975361-21975361	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.70C>A; p.Q24K; 5:22078607-22078607	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.17G>C; p.C6S; 5:22078660-22078660	thyroid	carcinoma	Substitution - Missense
c.2019C>T; p.F673F; 5:21752103-21752103	central_nervous_system; brain	glioma	Substitution - coding silent
c.256G>A; p.E86K; 5:21975361-21975361	breast	carcinoma	Substitution - Missense
c.109G>T; p.E37*; 5:22078568-22078568	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.109G>T; p.E37*; 5:22078568-22078568	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.663T>C; p.A221A; 5:21842312-21842312	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1541A>G; p.D514G; 5:21760650-21760650	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1324G>A; p.A442T; 5:21783427-21783427	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1835T>G; p.L612R; 5:21755641-21755641	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.648T>C; p.G216G; 5:21842327-21842327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1906G>A; p.A636T; 5:21752216-21752216	liver	carcinoma	Substitution - Missense
c.1906G>A; p.A636T; 5:21752216-21752216	liver	carcinoma	Substitution - Missense
c.2088C>A; p.D696E; 5:21752034-21752034	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1199G>A; p.G400E; 5:21802224-21802224	skin	malignant_melanoma	Substitution - Missense
c.687C>T; p.V229V; 5:21842288-21842288	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1978T>A; p.Y660N; 5:21752144-21752144	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2335G>A; p.A779T; 5:21751787-21751787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1199G>A; p.G400E; 5:21802224-21802224	skin	malignant_melanoma	Substitution - Missense
c.201C>T; p.Y67Y; 5:22078476-22078476	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.2335G>A; p.A779T; 5:21751787-21751787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2335G>A; p.A779T; 5:21751787-21751787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.343A>C; p.R115R; 5:21975274-21975274	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1109C>T; p.T370M; 5:21802314-21802314	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.942A>G; p.G314G; 5:21817005-21817005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1769G>T; p.C590F; 5:21755707-21755707	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1644G>A; p.A548A; 5:21755832-21755832	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation