Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10016
Symbol

PDCD6

Synonymous

ALG-2|ALG2|PEF1B

Full name

programmed cell death 6

Gene description

apoptosis-linked gene 2 protein|probable calcium-binding protein ALG-2|programmed cell death protein 6

Cytoband

5p15.33

Gene type

protein-coding

Synonymous

MIM:601057; HGNC:HGNC:8765; Ensembl:ENSG00000249915; HPRD:03035; Vega:OTTHUMG00000090283

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.367G>A; p.G123S; 5:306760-306760

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.250G>C; p.E84Q; 5:306643-306643

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.154C>G; p.L52V; 5:272763-272763

breastcarcinomaSubstitution - Missense

c.360A>G; p.S120S; 5:306753-306753

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.23_34del12; p.A12_G15delAGPG; 5:271743-271754

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaDeletion - In frame

c.23_34del12; p.A12_G15delAGPG; 5:271743-271754

breastcarcinomaDeletion - In frame

c.247A>G; p.S83G; 5:306640-306640

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.291C>T; p.N97N; 5:306684-306684

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.427C>T; p.R143W; 5:311352-311352

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1delA; p.?; 5:271721-271721

prostatecarcinoma; adenocarcinomaUnknown

c.235G>A; p.G79S; 5:306628-306628

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.312G>T; p.R104R; 5:306705-306705

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.24C>T; p.P8P; 5:271744-271744

skinmalignant_melanomaSubstitution - coding silent

c.220C>A; p.R74S; 5:306613-306613

upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.500G>A; p.R167H; 5:314439-314439

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.259G>A; p.G87S; 5:306652-306652

pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.367+1G>A; p.?; 5:306761-306761

large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.259G>T; p.G87C; 5:306652-306652

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.460G>A; p.G154S; 5:311385-311385

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.306C>A; p.Y102*; 5:306699-306699

pleurapulmonary_blastomaSubstitution - Nonsense

c.271T>C; p.Y91H; 5:306664-306664

ovarycarcinomaSubstitution - Missense

c.438T>C; p.I146I; 5:311363-311363

thyroidother; neoplasmSubstitution - coding silent

c.438T>C; p.I146I; 5:311363-311363

breastcarcinomaSubstitution - coding silent

c.438T>C; p.I146I; 5:311363-311363

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.303G>T; p.T101T; 5:306696-306696

lungcarcinoma; small_cell_carcinomaSubstitution - coding silent

c.330C>T; p.I110I; 5:306723-306723

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.367G>T; p.G123C; 5:306760-306760

breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.553T>A; p.S185T; 5:314492-314492

livercarcinomaSubstitution - Missense

c.553T>A; p.S185T; 5:314492-314492

livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.139G>A; p.E47K; 5:272748-272748

breastcarcinomaSubstitution - Missense