Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10005
Symbol

ACOT8

Synonymous

HNAACTE|PTE-1|PTE-2|PTE1|PTE2|hACTE-III|hTE

Full name

acyl-CoA thioesterase 8

Gene description

HIV-Nef associated acyl-CoA thioesterase|acyl-coenzyme A thioesterase 8|choloyl-CoA hydrolase|choloyl-coenzyme A thioesterase|long-chain fatty-acyl-CoA hydrolase|palmitoyl-CoA hydrolase|peroxisomal acyl-CoA thioesterase 1|peroxisomal acyl-coenzyme A thioe

Cytoband

20q13.12

Gene type

protein-coding

Synonymous

MIM:608123; HGNC:HGNC:15919; Ensembl:ENSG00000101473; HPRD:06998; Vega:OTTHUMG00000033045

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.869G>A; p.R290Q; 20:45841929-45841929

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.463G>C; p.E155Q; 20:45848475-45848475

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.463G>C; p.E155Q; 20:45848475-45848475

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.649G>A; p.E217K; 20:45843719-45843719

 livercarcinomaSubstitution - Missense

c.567A>G; p.P189P; 20:45844342-45844342

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.784C>T; p.H262Y; 20:45843584-45843584

 skinmalignant_melanomaSubstitution - Missense

c.57C>T; p.P19P; 20:45857259-45857259

 skinmalignant_melanomaSubstitution - coding silent

c.225_226CC>TT; p.V75>?; 20:45855195-45855196

 large_intestine; coloncarcinoma; adenocarcinomaComplex

c.533T>C; p.I178T; 20:45844376-45844376

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.635G>A; p.R212Q; 20:45844274-45844274

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2_3insAGATG; p.?; 20:45857313-45857314

 eye; uveal_tractmalignant_melanomaUnknown

c.842-2A>G; p.?; 20:45841958-45841958

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.581C>T; p.P194L; 20:45844328-45844328

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.951C>A; p.S317R; 20:45841847-45841847

 thyroidother; neoplasmSubstitution - Missense

c.273_274insTGATT; p.L92fs*1; 20:45848664-45848665

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.172C>G; p.Q58E; 20:45855249-45855249

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.634C>T; p.R212W; 20:45844275-45844275

 livercarcinomaSubstitution - Missense

c.324G>A; p.S108S; 20:45848614-45848614

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.625G>A; p.V209M; 20:45844284-45844284

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.328C>T; p.R110C; 20:45848610-45848610

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.55C>T; p.P19S; 20:45857261-45857261

 skin; armmalignant_melanomaSubstitution - Missense

c.654C>T; p.G218G; 20:45843714-45843714

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.178G>A; p.V60M; 20:45855243-45855243

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.305G>A; p.R102Q; 20:45848633-45848633

 skinmalignant_melanomaSubstitution - Missense

c.56C>T; p.P19L; 20:45857260-45857260

 skinmalignant_melanomaSubstitution - Missense

c.544G>A; p.E182K; 20:45844365-45844365

 skinmalignant_melanomaSubstitution - Missense

c.850C>T; p.R284W; 20:45841948-45841948

 stomachadenocarcinomaSubstitution - Missense

c.160C>T; p.L54L; 20:45855261-45855261

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.32A>C; p.Q11P; 20:45857284-45857284

 breastcarcinomaSubstitution - Missense

c.153C>A; p.A51A; 20:45855268-45855268

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.377C>T; p.A126V; 20:45848561-45848561

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.672C>T; p.C224C; 20:45843696-45843696

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.170G>A; p.G57D; 20:45855251-45855251

 pancreascarcinomaSubstitution - Missense

c.409C>A; p.Q137K; 20:45848529-45848529

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.329G>A; p.R110H; 20:45848609-45848609

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.329G>A; p.R110H; 20:45848609-45848609

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.628C>T; p.R210*; 20:45844281-45844281

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.818A>G; p.Y273C; 20:45843550-45843550

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.628C>T; p.R210*; 20:45844281-45844281

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.720G>C; p.L240L; 20:45843648-45843648

 central_nervous_system; braingliomaSubstitution - coding silent

c.256C>T; p.R86W; 20:45855165-45855165

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.256C>T; p.R86W; 20:45855165-45855165

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.155A>G; p.K52R; 20:45855266-45855266

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.578C>T; p.S193F; 20:45844331-45844331

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.946G>A; p.E316K; 20:45841852-45841852

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.676G>A; p.V226M; 20:45843692-45843692

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.642T>C; p.Y214Y; 20:45844267-45844267

 livercarcinomaSubstitution - coding silent

c.642T>C; p.Y214Y; 20:45844267-45844267

 livercarcinomaSubstitution - coding silent

c.126C>T; p.F42F; 20:45857190-45857190

 skinmalignant_melanomaSubstitution - coding silent

c.648C>T; p.G216G; 20:45843720-45843720

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.129-5T>C; p.?; 20:45855297-45855297

 stomachadenocarcinomaUnknown

c.190C>G; p.L64V; 20:45855231-45855231

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.236C>T; p.S79F; 20:45855185-45855185

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.89_117del29; p.T30fs*34; 20:45857199-45857227

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaDeletion - Frameshift