lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1
Symbol	A1BG
Synonymous	A1B\|ABG\|GAB\|HYST2477
Full name	alpha-1-B glycoprotein
Gene description	HEL-S-163pA\|alpha-1B-glycoprotein\|epididymis secretory sperm binding protein Li 163pA
Cytoband	19q13.4
Gene type	protein-coding
Synonymous	MIM:138670; HGNC:HGNC:5; Ensembl:ENSG00000121410; HPRD:00726; Vega:OTTHUMG00000183507

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.559G>T; p.D187Y; 19:58352337-58352337	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.243C>G; p.F81L; 19:58353025-58353025	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.243C>G; p.F81L; 19:58353025-58353025	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1153G>C; p.G385R; 19:58350409-58350409	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.996G>C; p.A332A; 19:58350566-58350566	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.791T>C; p.F264S; 19:58351510-58351510	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.545G>A; p.C182Y; 19:58352351-58352351	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.105C>T; p.S35S; 19:58353163-58353163	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.782G>A; p.R261H; 19:58351519-58351519	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.554G>A; p.R185Q; 19:58352342-58352342	liver	carcinoma	Substitution - Missense
c.1350G>A; p.G450G; 19:58347483-58347483	liver	carcinoma	Substitution - coding silent
c.735C>T; p.R245R; 19:58351566-58351566	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.735C>T; p.R245R; 19:58351566-58351566	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.810C>T; p.A270A; 19:58351491-58351491	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.409G>A; p.A137T; 19:58352487-58352487	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.80C>T; p.T27M; 19:58353188-58353188	ovary	other; neoplasm	Substitution - Missense
c.394G>A; p.G132S; 19:58352502-58352502	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.376G>T; p.V126L; 19:58352520-58352520	thyroid	other; neoplasm	Substitution - Missense
c.607G>C; p.E203Q; 19:58352289-58352289	urinary_tract; bladder	carcinoma	Substitution - Missense
c.839G>T; p.R280L; 19:58351462-58351462	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1311G>C; p.E437D; 19:58347522-58347522	skin	malignant_melanoma	Substitution - Missense
c.568G>A; p.G190S; 19:58352328-58352328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812T>G; p.L271R; 19:58351489-58351489	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812T>G; p.L271R; 19:58351489-58351489	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812T>G; p.L271R; 19:58351489-58351489	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812T>G; p.L271R; 19:58351489-58351489	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.812T>G; p.L271R; 19:58351489-58351489	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1034G>A; p.R345H; 19:58350528-58350528	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.90C>A; p.S30R; 19:58353178-58353178	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.779A>G; p.D260G; 19:58351522-58351522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.445C>A; p.L149M; 19:58352451-58352451	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.417C>A; p.C139*; 19:58352479-58352479	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.571G>A; p.A191T; 19:58352325-58352325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>A; p.A191T; 19:58352325-58352325	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>A; p.A191T; 19:58352325-58352325	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.466C>A; p.H156N; 19:58352430-58352430	liver	carcinoma	Substitution - Missense
c.1397G>A; p.G466D; 19:58347436-58347436	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.466C>A; p.H156N; 19:58352430-58352430	liver	carcinoma	Substitution - Missense
c.1397G>A; p.G466D; 19:58347436-58347436	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.887C>T; p.P296L; 19:58351414-58351414	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.717G>A; p.V239V; 19:58351584-58351584	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.122C>T; p.P41L; 19:58353146-58353146	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1460C>A; p.P487H; 19:58347373-58347373	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.122C>T; p.P41L; 19:58353146-58353146	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1347C>T; p.P449P; 19:58347486-58347486	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.192G>A; p.G64G; 19:58353076-58353076	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.155A>G; p.H52R; 19:58353113-58353113	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	thyroid	other; neoplasm	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	thyroid	other; neoplasm	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	thyroid	other; neoplasm	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	thyroid	other; neoplasm	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.832A>C; p.T278P; 19:58351469-58351469	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.418C>T; p.R140*; 19:58352478-58352478	kidney	other; neoplasm	Substitution - Nonsense
c.525T>C; p.H175H; 19:58352371-58352371	central_nervous_system; brain	glioma	Substitution - coding silent
c.889G>A; p.V297I; 19:58351412-58351412	skin	malignant_melanoma	Substitution - Missense
c.281G>A; p.R94H; 19:58352987-58352987	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892G>A; p.E298K; 19:58351409-58351409	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.R245C; 19:58351568-58351568	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.R245C; 19:58351568-58351568	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1132G>A; p.D378N; 19:58350430-58350430	NS	malignant_melanoma	Substitution - Missense
c.883G>A; p.A295T; 19:58351418-58351418	stomach	adenocarcinoma	Substitution - Missense
c.883G>A; p.A295T; 19:58351418-58351418	breast	carcinoma	Substitution - Missense
c.760delA; p.R254fs*13; 19:58351541-58351541	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.553C>T; p.R185W; 19:58352343-58352343	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.844C>T; p.R282W; 19:58351457-58351457	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.844C>T; p.R282W; 19:58351457-58351457	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.306C>A; p.T102T; 19:58352962-58352962	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.480G>A; p.E160E; 19:58352416-58352416	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1456G>A; p.D486N; 19:58347377-58347377	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.452G>A; p.R151K; 19:58352444-58352444	skin	malignant_melanoma	Substitution - Missense
c.544T>A; p.C182S; 19:58352352-58352352	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1305G>A; p.L435L; 19:58347528-58347528	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.544T>A; p.C182S; 19:58352352-58352352	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.781C>T; p.R261C; 19:58351520-58351520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.121_122insA; p.P41fs*33; 19:58353146-58353147	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.804G>T; p.A268A; 19:58351497-58351497	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1149C>T; p.F383F; 19:58350413-58350413	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1390C>T; p.H464Y; 19:58347443-58347443	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.770C>A; p.T257N; 19:58351531-58351531	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.674G>A; p.G225D; 19:58351627-58351627	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1159G>A; p.A387T; 19:58350403-58350403	pancreas	carcinoma	Substitution - Missense
c.1278C>A; p.P426P; 19:58347555-58347555	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.871T>G; p.S291A; 19:58351430-58351430	pancreas	carcinoma	Substitution - Missense
c.891C>T; p.V297V; 19:58351410-58351410	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.268C>T; p.R90C; 19:58353000-58353000	breast	carcinoma	Substitution - Missense
c.1334C>T; p.T445M; 19:58347499-58347499	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.393delC; p.G132fs*2; 19:58352503-58352503	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.570C>T; p.G190G; 19:58352326-58352326	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1017G>T; p.E339D; 19:58350545-58350545	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.570C>T; p.G190G; 19:58352326-58352326	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.570C>T; p.G190G; 19:58352326-58352326	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.347T>A; p.L116*; 19:58352549-58352549	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1422C>T; p.S474S; 19:58347411-58347411	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1152G>A; p.G384G; 19:58350410-58350410	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.803C>T; p.A268V; 19:58351498-58351498	liver	carcinoma	Substitution - Missense
c.803C>T; p.A268V; 19:58351498-58351498	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.803C>T; p.A268V; 19:58351498-58351498	liver	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation