| Gene ID | 6885 |
| Symbol | MAP3K7 |
| Synonymous | MEKK7|TAK1|TGF1a |
| Full name | mitogen-activated protein kinase kinase kinase 7 |
| Gene description | TGF-beta activated kinase 1|TGF-beta-activated kinase 1|transforming growth factor-beta-activated kinase 1 |
| Cytoband | 6q15 |
| Gene type | protein-coding |
| Synonymous | MIM:602614; HGNC:HGNC:6859; Ensembl:ENSG00000135341; HPRD:04011; Vega:OTTHUMG00000015217 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Presenilin action in Notch and Wnt signaling;PID Curated;200052 |
Pathway | nfkb activation by nontypeable hemophilus influenzae;PID BioCarta;100088 |
Pathway | thrombin signaling and protease-activated receptors;PID BioCarta;100082 |
Pathway | alk in cardiac myocytes;PID BioCarta;100244 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Downstream TCR signaling;PID Reactome;500482 |
Pathway | tgf beta signaling pathway;PID BioCarta;100017 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | BCR signaling pathway;PID Curated;200005 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | BMP receptor signaling;PID Curated;200123 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Pathway | nf-kb signaling pathway;PID BioCarta;100097 |
Pathway | Ephrin B reverse signaling;PID Curated;200173 |
Pathway | Adherens junction;KEGG PATHWAY;hsa04520 |
Pathway | fas signaling pathway (cd95);PID BioCarta;100167 |
Pathway | JNK signaling in the CD4+ TCR pathway;PID Curated;200129 |
Pathway | wnt signaling pathway;PID BioCarta;100002 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade;PID Reactome;500449 |
Pathway | IL1-mediated signaling events;PID Curated;200075 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | p38 MAPK signaling pathway;PID Curated;200014 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Interleukin-1 signaling;PID Reactome;500490 |
Pathway | Leishmaniasis;KEGG PATHWAY;hsa05140 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Disease | IMMUNE;GAD |
Disease | Celiac Disease;GAD |
Disease | smoking cessation;GAD |
Disease | CHEMDEPENDENCY;GAD |
Sequence Information | |
|---|---|
Nucleotide Sequence | >6885 : length: 5172 GTCCTCTCTCGCGGTATCATCCGGTTGCTGAGGCCCTGTAATAAAGGTCTCGCGAAATTTGTTCTAGAGGTCCAAGTTTGCTTCTTAGCTTACTCCACCCCACCCCCAACCTGTCCCTCC TTTTCTTTCCAAGTCACAAAATTCTCCCCTCCCCTACCCCGGAGTTTACGGCCCTCCTCCTGTTTCCGATTTCAGCCCGGAACCGGAAGTGTAGTGGGCGGGGCCCGTCGGCGGAAAACG CAGCGGAGCCAGAGCCGGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGCGGGTGGGCGCGGGT CTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGC CCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGGTTGTTGGAAGAGGAGCCTTTGGAGTTGTTTGCAAAGCTAAGTGGAGAGCAAAAGATGTTGC TATTAAACAAATAGAAAGTGAATCTGAGAGGAAAGCGTTTATTGTAGAGCTTCGGCAGTTATCCCGTGTGAACCATCCTAATATTGTAAAGCTTTATGGAGCCTGCTTGAATCCAGTGTG TCTTGTGATGGAATATGCTGAAGGGGGCTCTTTATATAATGTGCTGCATGGTGCTGAACCATTGCCATATTATACTGCTGCCCACGCAATGAGTTGGTGTTTACAGTGTTCCCAAGGAGT GGCTTATCTTCACAGCATGCAACCCAAAGCGCTAATTCACAGGGACCTGAAACCACCAAACTTACTGCTGGTTGCAGGGGGGACAGTTCTAAAAATTTGTGATTTTGGTACAGCCTGTGA CATTCAGACACACATGACCAATAACAAGGGGAGTGCTGCTTGGATGGCACCTGAAGTTTTTGAAGGTAGTAATTACAGTGAAAAATGTGACGTCTTCAGCTGGGGTATTATTCTTTGGGA AGTGATAACGCGTCGGAAACCCTTTGATGAGATTGGTGGCCCAGCTTTCCGAATCATGTGGGCTGTTCATAATGGTACTCGACCACCACTGATAAAAAATTTACCTAAGCCCATTGAGAG CCTGATGACTCGTTGTTGGTCTAAAGATCCTTCCCAGCGCCCTTCAATGGAGGAAATTGTGAAAATAATGACTCACTTGATGCGGTACTTTCCAGGAGCAGATGAGCCATTACAGTATCC TTGTCAGTATTCAGATGAAGGACAGAGCAACTCTGCCACCAGTACAGGCTCATTCATGGACATTGCTTCTACAAATACGAGTAACAAAAGTGACACTAATATGGAGCAAGTTCCTGCCAC AAATGATACTATTAAGCGCTTAGAATCAAAATTGTTGAAAAATCAGGCAAAGCAACAGAGTGAATCTGGACGTTTAAGCTTGGGAGCCTCCCGTGGGAGCAGTGTGGAGAGCTTGCCCCC AACCTCTGAGGGCAAGAGGATGAGTGCTGACATGTCTGAAATAGAAGCTAGGATCGCCGCAACCACAGCCTATTCCAAGCCTAAACGGGGCCACCGTAAAACTGCTTCATTTGGCAACAT TCTGGATGTCCCTGAGATCGTCATATCAGGCAACGGACAGCCAAGACGTAGATCCATCCAAGACTTGACTGTAACTGGAACAGAACCTGGTCAGGTGAGCAGTAGGTCATCCAGTCCCAG TGTCAGAATGATTACTACCTCAGGACCAACCTCAGAAAAGCCAACTCGAAGTCATCCATGGACCCCTGATGATTCCACAGATACCAATGGATCAGATAACTCCATCCCAATGGCTTATCT TACACTGGATCACCAACTACAGCCTCTAGCACCGTGCCCAAACTCCAAAGAATCTATGGCAGTGTTTGAACAGCATTGTAAAATGGCACAAGAATATATGAAAGTTCAAACAGAAATTGC ATTGTTATTACAGAGAAAGCAAGAACTAGTTGCAGAACTGGACCAGGATGAAAAGGACCAGCAAAATACATCTCGCCTGGTACAGGAACATAAAAAGCTTTTAGATGAAAACAAAAGCCT TTCTACTTACTACCAGCAATGCAAAAAACAACTAGAGGTCATCAGAAGTCAGCAGCAGAAACGACAAGGCACTTCATGATTCTCTGGGACCGTTACATTTTGAAATATGCAAAGAAAGAC TTTTTTTTTAAGGAAAGGAAAACCTTATAATGACGATTCATGAGTGTTAGCTTTTTGGCGTGTTCTGAATGCCAACTGCCTATATTTGCTGCATTTTTTTCATTGTTTATTTTCCTTTTC TCATGGTGGACATACAATTTTACTGTTTCATTGCATAACATGGTAGCATCTGTGACTTGAATGAGCAGCACTTTGCAACTTCAAAACAGATGCAGTGAACTGTGGCTGTATATGCATGCT CATTGTGTGAAGGCTAGCCTAACAGAACAGGAGGTATCAAACTAGCTGCTATGTGCAAACAGCGTCCATTTTTTCATATTAGAGGTGGAACCTCAAGAATGACTTTATTCTTGTATCTCA TCTCAAAATATTAATAATTTTTTTCCCAAAAGATGGTATATACCAAGTTAAAGACAGGGTATTATAAATTTAGAGTGATTGGTGGTATATTACGGAAATACGGAACCTTTAGGGATAGTT CCGTGTAAGGGCTTTGATGCCAGCATCCTTGGATCAGTACTGAACTCAGTTCCATCCGTAAAATATGTAAAGGTAAGTGGCAGCTGCTCTATTTAATGAAAGCAGTTTTACCGGATTTTG TTAGACTAAAATTTGATTGTGATACATTGAACAAAATGGAACTCATTTTTTTTTAAGGAGTAAAGATTTTTAATTCTGTGATTGTGTGTATGTGTGTTGAAACTGTAAAGCTTTTATGAC TCTAATATTAATCTCTTAAATGAAATTAAAAGGCAAAAGAACATGATTGAGCTTAAATGATCATTTCTTCCTGCAGTGATTCTTGGATTGTTTTCTCATGTATTTGAAAAAAAAAAAATG AAGAAAAATAATGGAAAATGGAAGTAATTACTCCAGCTAAAAAAAGCTTGGACTTAGATTTCTTTTTATGATACCAAATGAGAAATAAACCAGGCAAATCAGAAGGAAGTTAAAGAAGCA AATATAAATTCAACAAGTGTCCTAATTATCCTGGATATTGGAATATTTGATTTTCCTTACAATCCCGTTCTAGAATGCCTGCCGCCTTTCAACACTTTCAAGAGAATTTCAACACTTACA GAGTATTTATATTGTTAACAGTAATTTTGCTACCAAAACCTTCAGAATAACTTTAATAATAAAATGACACTGAAATAATAGACTATACAAACTCTATATTTTTTCAGTTGGTGTTAAAAT AAGTCACATTTTGATACCAGTACAAGATGTCTTTTAAATAAGGATGTCATCAGTCTGATTTTTATAGCATTAATGTTTTATGAAGAAAAAGTTCAAAATGAAAGCATTAATTGCTGTGAT TATTAGAATTCTATCATGACTGTATTGTAGTTTTTGCTCTATTTCAGATAAGCAAGATCTAAGAAGTTATCAAAACTATTCTTTAAAATGCTAAAGCAGGTAACTTTTTCTTCCATTATT TTTTCCTCCTACCACTGAGTTTTGTAATGAATTCCTTGTGTATACAAGCAATACAGGTGAATACTAAACTGTTATTTTTAGCTTCTTCAAAAGCTATTTTAGAAAGCTTCCTGGAAATAA ATGTCTTCTGTCATTTAATTTAAATAAAAGGAGTGTTAATTGTTCCCAAATTTGATTACCTAGCTGAAACAGATATTGGATTCAGCATAGTAATAGTAAAATAAAATTGGCAGAGAAAAT AACTGTAGACTAGGATAAAGCATGACTCCTCCATAGCATTGTTGCTTGTATGTACATCTGTCACTCCACTGAAAGGGACCTAGTCACTTTAAAGAGGCCTTTTATCTCAGCACGAGATAT CCAAGCGTGAATGCTAAGGCTTGATGTTTCCATTAGGATTTAGCATTCGAGATTTCAGATTTTATTTATAGTCATTGATGTGTTTTGCTGTATTATAACACATTTAAGGGAAATTTTATT ATGGTTTTTACATGTAGTCATTTCATAAAAATATCCAGATAGGTAAATGGAAGAAAATAGTAGATTTTAGTCATGGTACCAAATGCAAGAGGCTGTTGAACAGTTGCTTGTTTGTTTACA GTAAGTTCCTTGAGATTTTCAGTACTGTAGTTGCCCTGGACATTGAGTACAGTTCAGCCTTACTCTGTTTTTAAGTAGTTGTGTTGTCAATTTCATGCTTTTAAGTCCTGATGATCCTTG GAGATGGGAGAAAAAGATACCAGGGATAATTAAAATCCACAGCCAGTTTCATCAGTTTCCTCATCCATCCTGCAAATAAAAATGTTAACAAGGAGCCAAACTTATTCGTTCTGGTTTTAC AATTTATTTTGACCGTTTTTTGGGTGAAAATTGCAAACAGCCAAGCAAGTGGCTGGAATGCCCCAGTCTAAGAAATTCAAAAACAATCACTGAGTAAGCCCTAATTACATTAATTACATT TTACTCTTGACTCCAGGAAAAGAAAGCAAGCTTTTATCTAATCTAGAGGGAAGTATTCGTGAGCAATAAAAATCACTTTTTTGAGTTGAATAATAATCAGTTAAGAATATTTACCGCATA GCAACACAACATATAAAGATTTGTTACAAGTTGTTTACGGATGTTTGACTATTTTTGCTGAAGTATTTTAGAGTATTGAATGTCTTCTCTCTTCAAGTTTCTTTCATGTTCCTAATTTCA GCTCCTGTAGCCAGAGATCACAGGTCTTCCCTGTGAAACTTTGGTTTCTTTCTATAAATGTGTGTGGTTTTCAGCGCTCAACTCCTGTCTTCAAATGGTAGTAAGTTCTACTTCTACTTC TGTCATTCAGAACATTTTATGTCAAATGATGTAATGCAGAAATTCTTGTGCATATTTGTAACTGAAGGAAGCTTTTTAGATTTATTTTTGTTTTTAATAAAATTCAGATTCCTATTCTAA ACTGGTAAAAAA |
Protein Sequence | >6885 : length: 606 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHP WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ KRQGTS |