| Gene ID | 6696 |
| Symbol | SPP1 |
| Synonymous | BNSP|BSPI|ETA-1|OPN |
| Full name | secreted phosphoprotein 1 |
| Gene description | SPP1/CALPHA1 fusion|early T-lymphocyte activation 1|nephropontin|osteopontin|osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein|secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)|urinar |
| Cytoband | 4q22.1 |
| Gene type | protein-coding |
| Synonymous | MIM:166490; HGNC:HGNC:11255; Ensembl:ENSG00000118785; HPRD:01325; Vega:OTTHUMG00000130599 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Integrin cell surface interactions;PID Reactome;500004 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | regulators of bone mineralization;PID BioCarta;100089 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | Lupus erythematosus;FunDO |
Disease | Biliary Atresia;FunDO |
Disease | pseudoxanthoma elasticum;GAD |
Disease | Hepatitis C;FunDO |
Disease | Cancer;FunDO |
Disease | Eating disorder;FunDO |
Disease | HIV infection;FunDO |
Disease | Ulcerative colitis;FunDO |
Disease | Parkinson disease;FunDO |
Disease | intima-media thickness;GAD |
Disease | Herpes;FunDO |
Disease | Pancreatitis;FunDO |
Disease | IMMUNE;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | Inflammation of the central nervous system;FunDO |
Disease | rheumatoid arthritis;GAD |
Disease | systemic lupus erythematosus;GAD |
Disease | Nephrolithiasis;GAD |
Disease | Dental plaque;FunDO |
Disease | METABOLIC;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | asthma IgE;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Multiple sclerosis;FunDO |
Disease | CANCER;GAD |
Disease | Carotid Artery Diseases;GAD |
Disease | Kidney failure;FunDO |
Disease | hepatitis B liver cancer;GAD |
Disease | Heart failure;FunDO |
Disease | Enteritis;FunDO |
Disease | Osteoporosis;FunDO |
Disease | Lupus vulgaris;FunDO |
Disease | Obesity;FunDO |
Disease | Atherosclerosis;FunDO |
Sequence Information | |
|---|---|
Nucleotide Sequence | >6696 : length: 1823 CTCCCTGTGTTGGTGGAGGATGTCTGCAGCAGCATTTAAATTCTGGGAGGGCTTGGTTGTCAGCAGCAGCAGGAGGAGGCAGAGCACAGCATCGTCGGGACCAGACTCGTCTCAGGCCAG TTGCAGCCTTCTCAGCCAAACGCCGACCAAGGAAAACTCACTACCATGAGAATTGCAGTGATTTGCTTTTGCCTCCTAGGCATCACCTGTGCCATACCAGTTAAACAGGCTGATTCTGGA AGTTCTGAGGAAAAGCAGCACTAAAGATGTACCTACCCCTCCACAACAGATGAAACTGTGCCAGCCAAACAACAAATGGGCATTGTCCCCAGAAGCTTGGACAAAAAGGCACACAGAGTT CAATTCCAGTTGAACAGAATAAAGGCCAAAATAGAGCTGCCTTGGGGGTCACTGCAATTAGACTGCTTAATGAAGACATTAAAAGAACTTTACAACAAATACCCAGATGCTGTGGCCACA TGGCTAAACCCTGACCCATCTCAGAAGCAGAATCTCCTAGCCCCACAGAATGCTGTGTCCTCTGAAGAAACCAATGACTTTAAACAAGAGACCCTTCCAAGTAAGTCCAACGAAAGCCAT GACCACATGGATGATATGGATGATGAAGATGATGATGACCATGTGGACAGCCAGGACTCCATTGACTCGAACGACTCTGATGATGTAGATGACACTGATGATTCTCACCAGTCTGATGAG TCTCACCATTCTGATGAATCTGATGAACTGGTCACTGATTTTCCCACGGACCTGCCAGCAACCGAAGTTTTCACTCCAGTTGTCCCCACAGTAGACACATATGATGGCCGAGGTGATAGT GTGGTTTATGGACTGAGGTCAAAATCTAAGAAGTTTCGCAGACCTGACATCCAGTACCCTGATGCTACAGACGAGGACATCACCTCACACATGGAAAGCGAGGAGTTGAATGGTGCATAC AAGGCCATCCCCGTTGCCCAGGACCTGAACGCGCCTTCTGATTGGGACAGCCGTGGGAAGGACAGTTATGAAACGAGTCAGCTGGATGACCAGAGTGCTGAAACCCACAGCCACAAGCAG TCCAGATTATATAAGCGGAAAGCCAATGATGAGAGCAATGAGCATTCCGATGTGATTGATAGTCAGGAACTTTCCAAAGTCAGCCGTGAATTCCACAGCCATGAATTTCACAGCCATGAA GATATGCTGGTTGTAGACCCCAAAAGTAAGGAAGAAGATAAACACCTGAAATTTCGTATTTCTCATGAATTAGATAGTGCATCTTCTGAGGTCAATTAAAAGGAGAAAAAATACAATTTC TCACTTTGCATTTAGTCAAAAGAAAAAATGCTTTATAGCAAAATGAAAGAGAACATGAAATGCTTCTTTCTCAGTTTATTGGTTGAATGTGTATCTATTTGAGTCTGGAAATAACTAATG TGTTTGATAATTAGTTTAGTTTGTGGCTTCATGGAAACTCCCTGTAAACTAAAAGCTTCAGGGTTATGTCTATGTTCATTCTATAGAAGAAATGCAAACTATCACTGTATTTTAATATTT GTTATTCTCTCATGAATAGAAATTTATGTAGAAGCAAACAAAATACTTTTACCCACTTAAAAAGAGAATATAACATTTTATGTCACTATAATCTTTTGTTTTTTAAGTTAGTGTATATTT TGTTGTGATTATCTTTTTGTGGTGTGAATAAATCTTTTATCTTGAATGTAATAAGAATTTGGTGGTGTCAATTGCTTATTTGTTTTCCCACGGTTGTCCAGCAATTAATAAAACATAACC TTTTTTACTGCCTAAAAAAAAAA |
Protein Sequence | >6696 : length: 327 MGIVPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSND SDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYET SQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN |