| Gene ID | 5468 |
| Symbol | PPARG |
| Synonymous | CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma |
| Full name | peroxisome proliferator-activated receptor gamma |
| Gene description | PPAR-gamma|nuclear receptor subfamily 1 group C member 3|peroxisome proliferator-activated nuclear receptor gamma variant 1 |
| Cytoband | 3p25 |
| Gene type | protein-coding |
| Synonymous | MIM:601487; HGNC:HGNC:9236; Ensembl:ENSG00000132170; HPRD:03288; Vega:OTTHUMG00000129764 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | role of ppar-gamma coactivators in obesity and thermogenesis;PID BioCarta;100065 |
Pathway | basic mechanism of action of ppara pparb(d) and pparg and effects on gene expression;PID BioCarta;100064 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | Signaling events mediated by HDAC Class I;PID Curated;200070 |
Pathway | visceral fat deposits and the metabolic syndrome;PID BioCarta;100004 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | PPAR signaling pathway;KEGG PATHWAY;hsa03320 |
Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Thyroid cancer;KEGG PATHWAY;hsa05216 |
Disease | Thyroid cancer;KEGG DISEASE;H00032 |
Disease | Type 2 diabetes;NHGRI |
Disease | Body Weight;GAD |
Disease | increased antilipolytic insulin sensitivity;GAD |
Disease | metabolic syndrome;GAD |
Disease | Obesity, severe;OMIM |
Disease | cardiovascular;GAD |
Disease | lipids;GAD |
Disease | cholesterol, HDL;GAD |
Disease | Diabetes, type 2;OMIM |
Disease | exercise-mediated changes of insulin resistance;GAD |
Disease | edema;GAD |
Disease | obesity;GAD |
Disease | triglycerides;GAD |
Disease | Increased plasma concentrations of total cholesterol;GAD |
Disease | Diabetes;KEGG DISEASE |
Disease | Essential Hypertension;GAD |
Disease | oxidized low-density lipoprotein and cardiolipin autoantibodies;GAD |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Insulin resistance, severe, digenic;OMIM |
Disease | IMMUNE;GAD |
Disease | waist circumference;GAD |
Disease | glucose;GAD |
Disease | Cancers of endocrine organs;KEGG DISEASE |
Disease | Familial partial lipodystrophy;KEGG DISEASE;H00420 |
Disease | PHARMACOGENOMIC;GAD |
Disease | birth weight preterm delivery;GAD |
Disease | body mass energy metabolism;GAD |
Disease | METABOLIC;GAD |
Disease | LDL-cholesterol;GAD |
Disease | Carotid intimal medial thickness 1;OMIM |
Disease | Lipodystrophy, familial partial, type 3;OMIM |
Disease | colorectal cancer;GAD |
Disease | Bone Mineral Density;GAD |
Disease | Insulin Resistance;GAD |
Disease | type 2 diabetes;GAD |
Disease | diabetes, type 2;GAD |
Disease | higher body mass index;GAD |
Disease | diabetes, type 1;GAD |
Disease | Coronary Artery Disease;GAD |
Disease | larger body mass;GAD |
Disease | Peripheral Vascular Diseases;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | insulin;GAD |
Disease | Other genetic disorders;KEGG DISEASE |
Disease | NORMALVARIATION;GAD |
Disease | higher levels of serum leptin;GAD |
Disease | cholesterol, LDL;GAD |
Disease | lower lipoprotein lipase activity;GAD |
Disease | cardiovascular risk factors;GAD |
Disease | Obesity, resistance to;OMIM |
Disease | height;GAD |
Disease | atherosclerosis, generalized;GAD |
Disease | hyperglycemia insulin;GAD |
Disease | Glioblastoma, susceptibility to;OMIM |
Disease | REPRODUCTION;GAD |
Disease | Cancers;KEGG DISEASE |
Disease | Metabolic diseases;KEGG DISEASE |
Disease | body mass;GAD |
Disease | Hypertension/complications*;GAD |
Disease | CANCER;GAD |
Disease | HDL cholesterol/ BMI;GAD |
Disease | Obesity, Morbid;GAD |
Disease | Type II diabetes mellitus;KEGG DISEASE;H00409 |
Disease | cholesterol, total;GAD |
Disease | insulin sensitivity and body composition;GAD |
Disease | myocardial infarct;GAD |
Sequence Information | |
|---|---|
Nucleotide Sequence | >5468 : length: 1939 TGGGCTCCTGCAAGTGCCAGGCGCTGACCACTCCTCCTGGGAGCCTAACTGAGGGGGGTAGAGGCAGCAGAGGTTAACAGAAATCTCAGGTCCCTTGGTGGAAGGTGGGTGTGTAGTCGT GGTACTTTACGCCTCGGTGTTTAGGGAGGAGCCTAAGGTAAGGAGTCAGAAACGGGGAGTAACCGAGCTGCGGCTTTTATATAAGGTCAGTGGTAGGTAAGGAAGGGGCCTTAACCTCTG CTGGTGACCAGAAGCCTGCATTTCTGCATTCTGCTTAATTCCCTTTCCTTAGAAATGACCATGGTTGACACAGAGATGCCATTCTGGCCCACCAACTTTGGGATCAGCTCCGTGGATCTC TCCGTAATGGAAGACCACTCCCACTCCTTTGATATCAAGCCCTTCACTACTGTTGACTTCTCCAGCATTTCTACTCCACATTACGAAGACATTCCATTCACAAGAACAGATCCAGTGGTT GCAGATTACAAGTATGACCTGAAACTTCAAGAGTACCAAAGTGCAATCAAAGTGGAGCCTGCATCTCCACCTTATTATTCTGAGAAGACTCAGCTCTACAATAAGCCTCATGAAGAGCCT TCCAACTCCCTCATGGCAATTGAATGTCGTGTCTGTGGAGATAAAGCTTCTGGATTTCACTATGGAGTTCATGCTTGTGAAGGATGCAAGGGTTTCTTCCGGAGAACAATCAGATTGAAG CTTATCTATGACAGATGTGATCTTAACTGTCGGATCCACAAAAAAAGTAGAAATAAATGTCAGTACTGTCGGTTTCAGAAATGCCTTGCAGTGGGGATGTCTCATAATGCCATCAGGTTT GGGCGGATGCCACAGGCCGAGAAGGAGAAGCTGTTGGCGGAGATCTCCAGTGATATCGACCAGCTGAATCCAGAGTCCGCTGACCTCCGGGCCCTGGCAAAACATTTGTATGACTCATAC ATAAAGTCCTTCCCGCTGACCAAAGCAAAGGCGAGGGCGATCTTGACAGGAAAGACAACAGACAAATCACCATTCGTTATCTATGACATGAATTCCTTAATGATGGGAGAAGATAAAATC AAGTTCAAACACATCACCCCCCTGCAGGAGCAGAGCAAAGAGGTGGCCATCCGCATCTTTCAGGGCTGCCAGTTTCGCTCCGTGGAGGCTGTGCAGGAGATCACAGAGTATGCCAAAAGC ATTCCTGGTTTTGTAAATCTTGACTTGAACGACCAAGTAACTCTCCTCAAATATGGAGTCCACGAGATCATTTACACAATGCTGGCCTCCTTGATGAATAAAGATGGGGTTCTCATATCC GAGGGCCAAGGCTTCATGACAAGGGAGTTTCTAAAGAGCCTGCGAAAGCCTTTTGGTGACTTTATGGAGCCCAAGTTTGAGTTTGCTGTGAAGTTCAATGCACTGGAATTAGATGACAGC GACTTGGCAATATTTATTGCTGTCATTATTCTCAGTGGAGACCGCCCAGGTTTGCTGAATGTGAAGCCCATTGAAGACATTCAAGACAACCTGCTACAAGCCCTGGAGCTCCAGCTGAAG CTGAACCACCCTGAGTCCTCACAGCTGTTTGCCAAGCTGCTCCAGAAAATGACAGACCTCAGACAGATTGTCACGGAACACGTGCAGCTACTGCAGGTGATCAAGAAGACGGAGACAGAC ATGAGTCTTCACCCGCTCCTGCAGGAGATCTACAAGGACTTGTACTAGCAGAGAGTCCTGAGCCACTGCCAACATTTCCCTTCTTCCAGTTGCACTATTCTGAGGGAAAATCTGACACCT AAGAAATTTACTGTGAAAAAGCATTTTAAAAAGAAAAGGTTTTAGAATATGATCTATTTTATGCATATTGTTTATAAAGACACATTTACAATTTACTTTTAATATTAAAAATTACCATAT TATGAAATTGCTGATAGTA |
Protein Sequence | >5468 : length: 505 MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL LQVIKKTETDMSLHPLLQEIYKDLY |