| Gene ID | 5154 |
| Symbol | PDGFA |
| Synonymous | PDGF-A|PDGF1 |
| Full name | platelet-derived growth factor alpha polypeptide |
| Gene description | PDGF A-chain|PDGF subunit A|PDGF-1|platelet-derived growth factor A chain|platelet-derived growth factor alpha chain|platelet-derived growth factor alpha isoform 2 preproprotein|platelet-derived growth factor subunit A |
| Cytoband | 7p22 |
| Gene type | protein-coding |
| Synonymous | MIM:173430; HGNC:HGNC:8799; Ensembl:ENSG00000197461; HPRD:01424; Vega:OTTHUMG00000151412 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Melanoma;KEGG PATHWAY;hsa05218 |
Pathway | Glioma;KEGG PATHWAY;hsa05214 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | role of pi3k subunit p85 in regulation of actin organization and cell migration;PID BioCarta;100211 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | pdgf signaling pathway;PID BioCarta;100077 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | Ceramide signaling pathway;PID Curated;200100 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | phospholipids as signalling intermediaries;PID BioCarta;100183 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Disease | Cancers of the nervous system;KEGG DISEASE |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of the lung and pleura;KEGG DISEASE |
Disease | Glioma;KEGG DISEASE;H00042 |
Disease | Cancer;FunDO |
Disease | Endometriosis;FunDO |
Disease | Malignant pleural mesothelioma;KEGG DISEASE;H00015 |
Sequence Information | |
|---|---|
Nucleotide Sequence | >5154 : length: 2809 ACGCGCGCCCTGCGGAGCCCGCCCAACTCCGGCGAGCCGGGCCTGCGCCTACTCCTCCTCCTCCTCTCCCGGCGGCGGCTGCGGCGGAGGCGCCGACTCGGCCTTGCGCCCGCCCTCAGG CCCGCGCGGGCGGCGCAGCGAGGCCCCGGGCGGCGGGTGGTGGCTGCCAGGCGGCTCGGCCGCGGGCGCTGCCCGGCCCCGGCGAGCGGAGGGCGGAGCGCGGCGCCGGAGCCGAGGGCG CGCCGCGGAGGGGGTGCTGGGCCGCGCTGTGCCCGGCCGGGCGGCGGCTGCAAGAGGAGGCCGGAGGCGAGCGCGGGGCCGGCGGTGGGCGCGCAGGGCGGCTCGCAGCTCGCAGCCGGG GCCGGGCCAGGCGTCCAGGCAGGTGATCGGTGTGGCGGCGGCGGCGGCGGCGGCCCCAGACTCCCTCCGGAGTTCTTCTTGGGGCTGATGTCCGCAAATATGCAGAATTACCGGCCGGGT CGCTCCTGAAGCCAGCGCGGGGAGCGAGCGCGGCGGCGGCCAGCACCGGGAACGCACCGAGGAAGAAGCCCAGCCCCCGCCCTCCGCCCCTTCCGTCCCCACCCCCTACCCGGCGGCCCA GGAGGCTCCCCGCGCTGCGGGCGCGCACTCCCTGTTTCTCCTCCTCCTGGCTGGCGCTGCCTGCCTCTCCGCACTCACTGCTCGCGCCGGGCGCGCTCCGCCAGCTCCGTGCTCCCCGCG CCACCCTCCTCCGGGCCGCGCTCCCTAAGGGATGGTACTGAATTTCGCCGCCACAGGAGACCGGCTGGAGCGCCCGCCCCGCGGCCTCGCCTCTCCTCCGAGCAGCCAGCGCCTCGGGAC GCGATGAGGACCTTGGCTTGCCTGCTGCTCCTCGGCTGCGGATACCTCGCCCATGTTCTGGCCGAGGAAGCCGAGATCCCCCGCGAGGTGATCGAGAGGCTGGCCCGCAGTCAGATCCAC AGCATCCGGGACCTCCAGCGACTCCTGGAGATAGACTCCGTAGGGAGTGAGGATTCTTTGGACACCAGCCTGAGAGCTCACGGGGTCCATGCCACTAAGCATGTGCCCGAGAAGCGGCCC CTGCCCATTCGGAGGAAGAGAAGCATCGAGGAAGCTGTCCCCGCTGTCTGCAAGACCAGGACGGTCATTTACGAGATTCCTCGGAGTCAGGTCGACCCCACGTCCGCCAACTTCCTGATC TGGCCCCCGTGCGTGGAGGTGAAACGCTGCACCGGCTGCTGCAACACGAGCAGTGTCAAGTGCCAGCCCTCCCGCGTCCACCACCGCAGCGTCAAGGTGGCCAAGGTGGAATACGTCAGG AAGAAGCCAAAATTAAAAGAAGTCCAGGTGAGGTTAGAGGAGCATTTGGAGTGCGCCTGCGCGACCACAAGCCTGAATCCGGATTATCGGGAAGAGGACACGGGAAGGCCTAGGGAGTCA GGTAAAAAACGGAAAAGAAAAAGGTTAAAACCCACCTAAAGCAGCCAACCAGATGTGAGGTGAGGATGAGCCGCAGCCCTTTCCTGGGACATGGATGTACATGGCGTGTTACATTCCTGA ACCTACTATGTACGGTGCTTTATTGCCAGTGTGCGGTCTTTGTTCTCCTCCGTGAAAAACTGTGTCCGAGAACACTCGGGAGAACAAAGAGACAGTGCACATTTGTTTAATGTGACATCA AAGCAAGTATTGTAGCACTCGGTGAAGCAGTAAGAAGCTTCCTTGTCAAAAAGAGAGAGAGAGAAAGAGAGAGAGAAAACAAAACCACAAATGACAAAAACAAAACGGACTCACAAAAAT ATCTAAACTCGATGAGATGGAGGGTCGCCCCGTGGGATGGAAGTGCAGAGGTCTCAGCAGACTGGATTTCTGTCCGGGTGGTCACAGGTGCTTTTTTGCCGAGGATGCAGAGCCTGCTTT GGGAACGACTCCAGAGGGGTGCTGGTGGGCTCTGCAGGGGCCCGCAGGAAGCAGGAATGTCTTGGAAACCGCCACGCGAACTTTAGAAACCACACCTCCTCGCTGTAGTATTTAAGCCCA TACAGAAACCTTCCTGAGAGCCTTAAGTGGTTTTTTTTTTTGTTTTTGTTTTGTTTTTTTTTTTTTTGTTTTTTTTTTTTTTTTTTTACACCATAAAGTGATTATTAAGCTTTCCTTTTT ACTCTTTGGCTAGCTTTTTTTTTTTTTTTTTTTTTTTAATTATCTCTTGGATGACATTTACACCGATAACACACAGGCTGCTGTAACTGTCAGGACAGTGCGACGGTATTTTTCCTAGCA AGATGCAAACTAATGAGATGTATTAAAATAAACATGGTATACCTACCTATGCATCATTTCCTAAATGTTTCTGGCTTTGTGTTTCTCCCTTACCCTGCTTTATTTGTTAATTTAAGCCAT TTTGAAAGAACTATGCGTCAACCAATCGTACGCCGTCCCTGCGGCACCTGCCCCAGAGCCCGTTTGTGGCTGAGTGACAACTTGTTCCCCGCAGTGCACACCTAGAATGCTGTGTTCCCA CGCGGCACGTGAGATGCATTGCCGCTTCTGTCTGTGTTGTTGGTGTGCCCTGGTGCCGTGGTGGCGGTCACTCCCTCTGCTGCCAGTGTTTGGACAGAACCCAAATTCTTTATTTTTGGT AAGATATTGTGCTTTACCTGTATTAACAGAAATGTGTGTGTGTGGTTTGTTTTTTTGTAAAGGTGAAGTTTGTATGTTTACCTAATATTACCTGTTTTGTATACCTGAGAGCCTGCTATG TTCTTTTTTTGTTGATCCAAAATTAAAAAAAAAAATACCACCAACAAAA |
Protein Sequence | >5154 : length: 256 MWVEGPHSDAPGLGSWAGARGSRQETGWSARPAASPLLRAASASGRDEDLGLPAAPRLRIPRPCSGRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVP EKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGR PRESGKKRKRKRLKPT |