| Gene ID | 3611 |
| Symbol | ILK |
| Synonymous | HEL-S-28|ILK-1|ILK-2|P59|p59ILK |
| Full name | integrin-linked kinase |
| Gene description | 59 kDa serine/threonine-protein kinase|epididymis secretory protein Li 28|integrin-linked kinase-2|integrin-linked protein kinase |
| Cytoband | 11p15.4 |
| Gene type | protein-coding |
| Synonymous | MIM:602366; HGNC:HGNC:6040; Ensembl:ENSG00000166333; HPRD:03842; Vega:OTTHUMG00000133407 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | pten dependent cell cycle arrest and apoptosis;PID BioCarta;100058 |
Pathway | Cell-extracellular matrix interactions;PID Reactome;500123 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Localization of the PINCH-ILK-PARVIN complex to focal adhesions;PID Reactome;500124 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | PPAR signaling pathway;KEGG PATHWAY;hsa03320 |
Disease | Cancer;FunDO |
Sequence Information | |
|---|---|
Nucleotide Sequence | >3611 : length: 2098 AGCCCGAGTCCCGGTGAGTGCGAGAGGACCCGCGCCCCCTGTCACCCCTCACTTCTCCTGAGTCCCAAGTAAGGAACGGAGCCAACCCTGGGGAGGACCCCCGGTCCCCTCTCCCAGAGT ATACGGAGCCTGAACCTCCCCACTTCCCCCAACTCTGTTCGCGGATAGGGTCTAGTTGCCTGCTCTCGGACATCCGTTCAGCAGACACTACCTCTTCGTCACCCCCTGCCCACCCTGACC CGCCTTTACCTCGCGTCTAGAGGACACAGCCAGGGATCATCCCGCAGCCCCGAACTCCTTCACAGACCCCCACTAGCCGGGGACGCAGCTCAGGCCCCCTACCCCCAACACAAACACTTC TCTCCTGTAGAGGATAAAGCTTGGGGTTCATCCTCCTTCCCTGGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCACT CAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGC TCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTA TTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTC AGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGAC ACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAG CTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGATTTTCTCG CATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAAT TTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATG ATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGCTCTGCAGAAGAAGCCTGAA GACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGGCATTG GAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTT GAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCC AGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAG GGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAACAGGAAAAAAAAAAAAAA |
Protein Sequence | >3611 : length: 452 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK |