| Gene ID | 208 |
| Symbol | AKT2 |
| Synonymous | HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA |
| Full name | v-akt murine thymoma viral oncogene homolog 2 |
| Gene description | PKB beta|RAC-PK-beta|RAC-beta serine/threonine-protein kinase|murine thymoma viral (v-akt) homolog-2|protein kinase Akt-2|protein kinase B beta|rac protein kinase beta |
| Cytoband | 19q13.1-q13.2 |
| Gene type | protein-coding |
| Synonymous | MIM:164731; HGNC:HGNC:392; Ensembl:ENSG00000105221; HPRD:01262; Vega:OTTHUMG00000137375 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Class I PI3K signaling events mediated by Akt;PID Curated;200169 |
Pathway | Insulin/IGF pathway-protein kinase B signaling cascade;PANTHER;P00033 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | E-cadherin signaling in keratinocytes;PID Curated;200125 |
Pathway | Inhibition of TSC complex formation by PKB;PID Reactome;500906 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Inhibition of HSL;PID Reactome;501025 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Chronic myeloid leukemia;KEGG PATHWAY;hsa05220 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | Small cell lung cancer;KEGG PATHWAY;hsa05222 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Activation of PKB;PID Reactome;501026 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Carbohydrate digestion and absorption;KEGG PATHWAY;hsa04973 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | FAS signaling pathway;PANTHER;P00020 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Hypoxia response via HIF activation;PANTHER;P00030 |
Pathway | Regulation of beta-cell development;Reactome;REACT:13698 |
Pathway | Melanoma;KEGG PATHWAY;hsa05218 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | p53 pathway by glucose deprivation;PANTHER;P04397 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | PDE3B signalling;PID Reactome;500958 |
Pathway | Non-small cell lung cancer;KEGG PATHWAY;hsa05223 |
Pathway | Inhibition of HSL;Reactome;REACT:1123 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Glioma;KEGG PATHWAY;hsa05214 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Insulin-mediated glucose transport;PID Curated;200168 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | Hyperglycemia;FunDO |
Disease | Cancers;KEGG DISEASE |
Disease | Diabetes mellitus;FunDO |
Disease | Genetic disorders;KEGG DISEASE |
Disease | blood pressure, arterial cholesterol insulin resistance metabolic syndrome;GAD |
Disease | Congenital abnormality;FunDO |
Disease | Ovarian cancer;KEGG DISEASE;H00027 |
Disease | CARDIOVASCULAR;GAD |
Disease | Obesity;FunDO |
Disease | Familial partial lipodystrophy;KEGG DISEASE;H00420 |
Disease | Other genetic disorders;KEGG DISEASE |
Disease | Cancer;FunDO |
Disease | Diabetes mellitus, type II;OMIM |
Disease | Cancers of the breast and female genital organs;KEGG DISEASE |
Disease | Metabolism disease;FunDO |
Sequence Information | |
|---|---|
Nucleotide Sequence | >208 : length: 5317 TGGGAGGGGGCGGTAAGCGGGGGCTGGGGGGAGGGGGCGGGGGGGGCCGCGCCGTGCTAGCCGTTGGGCCTGCCTCGGAGGAGGCGTCGCCGCCGCCGCTGCCGCTGCCGGCGCCGTTGC CGCTGCCGGGAAACACAAGGAAAGGGAACCAGCGCAGCGTGGCGATGGGCGGGGGTAGAGCCCCGCCGGAGAGGCTGGGCGGCTGCCGGTGACAGACTGTGCCCTGTCCACGGTGCCTCC TGCATGTCCTGCTGCCCTGAGCTGTCCCGAGCTAGGTGACAGCGTACCACGCTGCCACCATGAATGAGGTGTCTGTCATCAAAGAAGGCTGGCTCCACAAGCGTGGTGAATACATCAAGA CCTGGAGGCCACGGTACTTCCTGCTGAAGAGCGACGGCTCCTTCATTGGGTACAAGGAGAGGCCCGAGGCCCCTGATCAGACTCTACCCCCCTTAAACAACTTCTCCGTAGCAGAATGCC AGCTGATGAAGACCGAGAGGCCGCGACCCAACACCTTTGTCATACGCTGCCTGCAGTGGACCACAGTCATCGAGAGGACCTTCCACGTGGATTCTCCAGACGAGAGGGAGGAGTGGATGC GGGCCATCCAGATGGTCGCCAACAGCCTCAAGCAGCGGGCCCCAGGCGAGGACCCCATGGACTACAAGTGTGGCTCCCCCAGTGACTCCTCCACGACTGAGGAGATGGAAGTGGCGGTCA GCAAGGCACGGGCTAAAGTGACCATGAATGACTTCGACTATCTCAAACTCCTTGGCAAGGGAACCTTTGGCAAAGTCATCCTGGTGCGGGAGAAGGCCACTGGCCGCTACTACGCCATGA AGATCCTGCGGAAGGAAGTCATCATTGCCAAGGATGAAGTCGCTCACACAGTCACCGAGAGCCGGGTCCTCCAGAACACCAGGCACCCGTTCCTCACTGCGCTGAAGTATGCCTTCCAGA CCCACGACCGCCTGTGCTTTGTGATGGAGTATGCCAACGGGGGTGAGCTGTTCTTCCACCTGTCCCGGGAGCGTGTCTTCACAGAGGAGCGGGCCCGGTTTTATGGTGCAGAGATTGTCT CGGCTCTTGAGTACTTGCACTCGCGGGACGTGGTATACCGCGACATCAAGCTGGAAAACCTCATGCTGGACAAAGATGGCCACATCAAGATCACTGACTTTGGCCTCTGCAAAGAGGGCA TCAGTGACGGGGCCACCATGAAAACCTTCTGTGGGACCCCGGAGTACCTGGCGCCTGAGGTGCTGGAGGACAATGACTATGGCCGGGCCGTGGACTGGTGGGGGCTGGGTGTGGTCATGT ACGAGATGATGTGCGGCCGCCTGCCCTTCTACAACCAGGACCACGAGCGCCTCTTCGAGCTCATCCTCATGGAAGAGATCCGCTTCCCGCGCACGCTCAGCCCCGAGGCCAAGTCCCTGC TTGCTGGGCTGCTTAAGAAGGACCCCAAGCAGAGGCTTGGTGGGGGGCCCAGCGATGCCAAGGAGGTCATGGAGCACAGGTTCTTCCTCAGCATCAACTGGCAGGACGTGGTCCAGAAGA AGCTCCTGCCACCCTTCAAACCTCAGGTCACGTCCGAGGTCGACACAAGGTACTTCGATGATGAATTTACCGCCCAGTCCATCACAATCACACCCCCTGACCGCTATGACAGCCTGGGCT TACTGGAGCTGGACCAGCGGACCCACTTCCCCCAGTTCTCCTACTCGGCCAGCATCCGCGAGTGAGCAGTCTGCCCACGCAGAGGACGCACGCTCGCTGCCATCACCGCTGGGTGGTTTT TTCCCCCTAACTTTTTACTTAGCCTTTTTGGTTTGTGTCCCCACCCCCACCTCCTCACCCCCTTTCCAGTTCTTCTTCAGGCCCCTCCCAGACGCACCCCAGCGGCCCCTGCAGCCCCTG CCTCCAGCCTCCAGCCTCACCTTTGTGCCCAGACTCGCATTTGGAAGACTCCACCTCCCGCCCAGGCCTGGGCTGTTGGGCGGTTGGAGATTCAGGTTTTAATCCACACAAGCCCCAGTG AGGGGTGAAGCATGGCGCCTGGGGCCTGCCTGAGTTTCTGGCCTGGGTGTCGTGCTGGTGTCTGCCTCCGCGCTGCTGCATCTGGACGAAGGCTGCCTTCTGGTGGGACGCGACACCCGG CAGACAGTGGTGCTGCCTTCCAGGCCCCGTGGCCTAGGCTCGGAGTGGCCAGGCACGGGGCGGTCCAATCCCCCACCCGCTGTCCCCCTATGGGGGCAGAAAAGCAATAATGTCCAGGGG CAGGCAGGGGCCCTTGGGAGCTGCAGGGCTGGGGGTTAGGGCTGCTCCCTGGTGAATGGAGTCAGATCCTAGGATCTGTACCATGGGGAACCAGGAGTGGCCGGGCTGGGTGCCGCCTCC TGGTCCGGCCTCCTCCCCACCAAACTGTCCTCACCCTATGGATGAGGCAGGAGGAACATTTGGGGCCAAACCTGCCTGCCTCCCAGCCCCGTGCCTTACTAGGGCTTCCTTCCAGCTGGC CTTACCTCCCGCTGGACCCTGGGCCTGGCCTGGCCCCACTGGGGGCTATGGGCTGGGCTCACCCTCTCCTCTGCGGGGGTGGAGGGCCACCAGCCTTGGCTGTTACAATCTTACACCGGA CAGTATTGGGCCCCATGGACTTGGTCAGGGAGGGGTGGGGGTGGGCATCTCTGGTACCTATTGGGGTGGGGGGCCTCTGAAAAGGGAGGCTCCTAGGCCCCCCTCACCCCTCCCTCTCCC CAGGGCCCCACGTTCTGCAGCCTTAAGGTTGAACATGAGTGCACGTCCATGTCAGTGCTGTGGGACTCCTGTGCGTGCCTCGGACTGCGTGTGTCGGCGGGACGCAGGCACACGTGGGTG TGTGTGCATGTGTGTTTGTGTGAGGGCAGCGTGTCCTCCAGTGTGCATGGTGTGTGGGCTTGGGCCCCATCCCTGGCCCGAGCATTTCATCCTGTGGGGGAGGGGTGCTGACCTAGTGGG AGGAGCCCCACTGTGATCCATGAGCTGCCCTGCCCACGCCTCCCCTCCCTGTAGCAACACCTCTGGGTGTTTGGAGTTTAGCTTTTGTGGGTTTGCTCTCCCTATCCCATCTCCTGTACT ACACAGTTCATGGCAGGGTGGGGAGGGGTGGGGTTGGTTCGGGTGGGTGAGGGTCTTTTTCCTCTGTGTGCGATGTTGTTATCTGACAGTTCTCCGTCCCTACTGGCCTTTCTCCTCGTC TTCATATTTGTACGGTACAAGCAATAAAGACACTCATTTCAGACCAGGGCCCAGCCTGCACTCACGCCAGCCCAACCACTCTGGGCTTTGCCTTGGTGATGGAGTCAGACCCCTGGGCCC CAGCTCCTCCTGTACTAGCCGTTCCCTTCAGCAAGGAGGGCACTGAGCTCAGGGTGAGGGCAGCTGGGGTGTGTGCAGGAGCTCAGGCTGGAGAGGGTGGGTGGAGCTGGTGCTGTGGGG CTGAGGGGTATGGGAAGGCTCCCCGCATGTGGGGGTGGGGTGGACAGAGACCACTCCAGGCCCTCAGTGCTGCTTAGGCTAAGAGAGGTGGGGTGGAGGGACAGGGCTGGAAGATCTGGG TAGCCCAGAATGAGGAGGGTGCCTGTGCTGTCACTGAATGAGAGGGAGTGGTTCATTCCACCCGGCTGCCGAGCCTCAGAGGGGGGCATTCCTATCCTGCCCCACCTCCCTGTTTATGCT GCCACCTGGAAGCCTTGAGGCCCCCAAATTCCAGTACAGACCCAGTGGTGTGTTCATGGTGGCGTGGTTGCTGTCACCTGGGAGCTCCTGAGCGTTTGGTTAGAACCCTGTTCAGCTTGG GGTCAGCCCTCCCCTAGTCACTGCCCTTTAGCCTGGATGTGTCTGGGCCCCTGCACTTCCCGTGCTTGAGTCACGTGGCTGCATGGCCGGGCGCTGGCCGGATGGAACACCTCCCCCAGC AAGGGACCAGGGACCAGAGCCCTGGCCTGCCCTGCTGAGCCCTGCTGTGCAGAGGGCCTGGCACAGATGAATTTGAGATTTTGCCGCAAGGTGTTAGCACTTCACACCCATTGAGTCTTT GAGATTTTAAGTGAATGTAAGCAGAAAAAGTCAGATCCAATTTACAGAAATCAGAGTTAGCTACAGCTAGGACTCGTTTGGTTGGGGTTTTTTAGTTTGTCTTTCTAAAGTCATGTGGAC CTTAATTTAATTACAAAAGTCTACCCTGGTGGTCATAAAATAGGCAGGCCTATGAAGAAAGGCCTTTTACTCTTCCATCTCGTCCCAGCCCCGAGTTGACCCACGTTGCTGCTCCTCACA CCATGGTGATGCAGGTCTCGTAGTGTGGGCACAGGCCTGGCTACCTCATCTTTTTAGTGCCTCTCTCCTCTTCCACAGGATGGGGTCCCACAGCTGCAGCAGCTGGCCCCGTAGTTGAGC ATGTGTGGTTATCCTGTAGAGCTTTTCCCAAGAAGGGTGTTTGAACTTAGAGTCTTAATAAAATCTTACCAAATAAATTTTGAGTAGAATAATCGTCTTTTGCAATGTACATTTTAAAAA TTTCACACATTCTTTTTTGTATATAAAGAACAGTGACTGGGCACAGTGGCTCATGCCTGTAATCCCAGCAATTTGGGAGGCCGAGGCGGGCGGGTCTCTTGAGGCCAGGGGTTCGAGACC AGCCTGGGCATCATAGGGAGACCTTCATCTCTACAAAAAATACAAAAATTAGCTGGGCATGGTGGTGCATGCCTGCAATCCCAGCTAACTTGGAAGGCTGAGGTGAGGTGGGAAGATCAC TTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGATTGCGGCACTGCACTGCAGCCTGGGACAATGAGACTGTGTCTCTAAAAATAAAAAAAAAAAAAACATGATACATGCTATTAAAA AAGACAGCAAAGCAGGAGTATAAGAAAGGAAATTCACCCGAGGTCGCAGGGCCTTGAGTACTCATTTTGGTGCTGATTACCTCTCTGCAAATGGACACGGCATCATAAATTGGTAGTTTC CTGCTCTTTTTGTGTAATCTTTTCCAGTTAATGTGAAGCCTCTGGGGGCTGCCCTCGTGCACTGATGGTTGTGTGGAGTCGGGGGCGGCAGTGCGATTCCCTTTTAGCTGCTGCATGGGG GGAACTCAGGCTTTCCAGCTGCTTCCTGGGGTTCCATGGGGTAGACCCCTCAACCGCTTCAGCTGCCCCGTTAACAGGAATTGACTTGGTTTCGTTTGGTGCTACCAGCAGTCCTGTAAT AAACTAGCTATCCATCTGTAAAAAAAAAAAAAAAAAA |
Protein Sequence | >208 : length: 481 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR E |