| Gene ID | 183 |
| Symbol | AGT |
| Synonymous | ANHU|SERPINA8 |
| Full name | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| Gene description | alpha-1 antiproteinase, antitrypsin|angiotensin I|angiotensin II|angiotensinogen|pre-angiotensinogen|serine (or cysteine) proteinase inhibitor|serpin A8 |
| Cytoband | 1q42.2 |
| Gene type | protein-coding |
| Synonymous | MIM:106150; HGNC:HGNC:333; Ensembl:ENSG00000135744; HPRD:00106; Vega:OTTHUMG00000037757 |
Pathways and Diseases | Detail |
|---|---|
Pathway | bioactive peptide induced signaling pathway;PID BioCarta;100226 |
Pathway | Peptide ligand-binding receptors;PID Reactome;500405 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | Renin-angiotensin system;KEGG PATHWAY;hsa04614 |
Pathway | angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236 |
Pathway | role of egf receptor transactivation by gpcrs in cardiac hypertrophy;PID BioCarta;100221 |
Pathway | Signaling events mediated by PRL;PID Curated;200006 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Disease | Preeclampsia, susceptibility to;OMIM |
Disease | Lupus erythematosus;FunDO |
Disease | Adenocarcinoma;FunDO |
Disease | serum concentrations of creatinine;GAD |
Disease | insulin response to oral glucose;GAD |
Disease | Renal tubular dysgenesis;OMIM |
Disease | Cardiovascular disease;FunDO |
Disease | cardiovascular;GAD |
Disease | Erythropoietin Induced Hypertension;GAD |
Disease | Myocardial Ischemia;GAD |
Disease | Hyperglycemia;FunDO |
Disease | Hypertension, essential, susceptibility to;OMIM |
Disease | Albuminuria;GAD |
Disease | Intermediate coronary syndrome;FunDO |
Disease | obesity;GAD |
Disease | Vascular dementia;FunDO |
Disease | PSYCH;GAD |
Disease | Henoch-Schoenlein purpura;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Depression;FunDO |
Disease | sleep apnea;GAD |
Disease | Essential Hypertension;GAD |
Disease | Esotropia;FunDO |
Disease | Hypercholesterolemia;FunDO |
Disease | restenosis after percutaneous transluminal coronary angioplasty;GAD |
Disease | Embryoma;FunDO |
Disease | AGING;GAD |
Disease | hypertension;GAD |
Disease | diabetes, type 1;GAD |
Disease | familial hypertension of early onset.;GAD |
Disease | Chronic rejection of renal transplant;FunDO |
Disease | atherosclerosis, coronary;GAD |
Disease | IMMUNE;GAD |
Disease | Mouth Neoplasms;GAD |
Disease | renal disease, end stage;GAD |
Disease | cardiovascular disease;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | Carcinoma, Squamous Cell;GAD |
Disease | blood pressure phenotypes.;GAD |
Disease | blood pressure;GAD |
Disease | End- Stage Renal Disease (ESRD);GAD |
Disease | Kidney disease;FunDO |
Disease | Cirrhosis;FunDO |
Disease | METABOLIC;GAD |
Disease | bipolar affective disorder;GAD |
Disease | menopause;GAD |
Disease | diabetes, type 2;GAD |
Disease | Hamman-Rich syndrome;FunDO |
Disease | power sports performance;GAD |
Disease | immunoglobin A nephropathy;GAD |
Disease | Proteinuria;FunDO |
Disease | preeclampsia;GAD |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | Abruptio Placentae;GAD |
Disease | coronary atherosclerosis.;GAD |
Disease | CANCER;GAD |
Disease | Myocardial Infarction;GAD |
Disease | angiotensinogen concentrations;GAD |
Disease | hypertension, pregnancy induced;GAD |
Disease | longevity;GAD |
Disease | Growth retardation;FunDO |
Disease | blood pressure, arterial;GAD |
Disease | Hepatitis B;FunDO |
Disease | nephropathy, diabetic;GAD |
Disease | IGA glomerulonephritis;FunDO |
Disease | coronary events;GAD |
Disease | Lupus vulgaris;FunDO |
Disease | Transient hypertension of pregnancy;FunDO |
Disease | Obesity;FunDO |
Disease | coronary heart disease;GAD |
Disease | cardiomyopathy;GAD |
Disease | Abruption placentae;FunDO |
Disease | coronary atherosclerosis;GAD |
Disease | dementia, vascular;GAD |
Disease | carotid intimal-medial thickening;GAD |
Disease | RENAL;GAD |
Sequence Information | |
|---|---|
Nucleotide Sequence | >183 : length: 2587 ATCCCATGAGCGGGCAGCAGGGTCAGAAGTGGCCCCCGTGTTGCCTAAGCAAGACTCTCCCCTGCCCTCTGCCCTCTGCACCTCCGGCCTGCATGTCCCTGTGGCCTCTTGGGGGTACAT CTCCCGGGGCTGGGTCAGAAGGCCTGGGTGGTTGGCCTCAGGCTGTCACACACCTAGGGAGATGCTCCCGTTTCTGGGAACCTTGGCCCCGACTCCTGCAAACTTCGGTAAATGTGTAAC TCGACCCTGCACCGGCTCACTCTGTTCAGCAGTGAAACTCTGCATCGATCACTAAGACTTCCTGGAAGAGGTCCCAGCGTGAGTGTCGCTTCTGGCATCTGTCCTTCTGGCCAGCCTGTG GTCTGGCCAAGTGATGTAACCCTCCTCTCCAGCCTGTGCACAGGCAGCCTGGGAACAGCTCCATCCCCACCCCTCAGCTATAAATAGGGCATCGTGACCCGGCCGGGGGAAGAAGCTGCC GTTGTTCTGGGTACTACAGCAGAAGGGTATGCGGAAGCGAGCACCCCAGTCTGAGATGGCTCCTGCCGGTGTGAGCCTGAGGGCCACCATCCTCTGCCTCCTGGCCTGGGCTGGCCTGGC TGCAGGTGACCGGGTGTACATACACCCCTTCCACCTCGTCATCCACAATGAGAGTACCTGTGAGCAGCTGGCAAAGGCCAATGCCGGGAAGCCCAAAGACCCCACCTTCATACCTGCTCC AATTCAGGCCAAGACATCCCCTGTGGATGAAAAGGCCCTACAGGACCAGCTGGTGCTAGTCGCTGCAAAACTTGACACCGAAGACAAGTTGAGGGCCGCAATGGTCGGGATGCTGGCCAA CTTCTTGGGCTTCCGTATATATGGCATGCACAGTGAGCTATGGGGCGTGGTCCATGGGGCCACCGTCCTCTCCCCAACGGCTGTCTTTGGCACCCTGGCCTCTCTCTATCTGGGAGCCTT GGACCACACAGCTGACAGGCTACAGGCAATCCTGGGTGTTCCTTGGAAGGACAAGAACTGCACCTCCCGGCTGGATGCGCACAAGGTCCTGTCTGCCCTGCAGGCTGTACAGGGCCTGCT AGTGGCCCAGGGCAGGGCTGATAGCCAGGCCCAGCTGCTGCTGTCCACGGTGGTGGGCGTGTTCACAGCCCCAGGCCTGCACCTGAAGCAGCCGTTTGTGCAGGGCCTGGCTCTCTATAC CCCTGTGGTCCTCCCACGCTCTCTGGACTTCACAGAACTGGATGTTGCTGCTGAGAAGATTGACAGGTTCATGCAGGCTGTGACAGGATGGAAGACTGGCTGCTCCCTGATGGGAGCCAG TGTGGACAGCACCCTGGCTTTCAACACCTACGTCCACTTCCAAGGGAAGATGAAGGGCTTCTCCCTGCTGGCCGAGCCCCAGGAGTTCTGGGTGGACAACAGCACCTCAGTGTCTGTTCC CATGCTCTCTGGCATGGGCACCTTCCAGCACTGGAGTGACATCCAGGACAACTTCTCGGTGACTCAAGTGCCCTTCACTGAGAGCGCCTGCCTGCTGCTGATCCAGCCTCACTATGCCTC TGACCTGGACAAGGTGGAGGGTCTCACTTTCCAGCAAAACTCCCTCAACTGGATGAAGAAACTATCTCCCCGGACCATCCACCTGACCATGCCCCAACTGGTGCTGCAAGGATCTTATGA CCTGCAGGACCTGCTCGCCCAGGCTGAGCTGCCCGCCATTCTGCACACCGAGCTGAACCTGCAAAAATTGAGCAATGACCGCATCAGGGTGGGGGAGGTGCTGAACAGCATTTTTTTTGA GCTTGAAGCGGATGAGAGAGAGCCCACAGAGTCTACCCAACAGCTTAACAAGCCTGAGGTCTTGGAGGTGACCCTGAACCGCCCATTCCTGTTTGCTGTGTATGATCAAAGCGCCACTGC CCTGCACTTCCTGGGCCGCGTGGCCAACCCGCTGAGCACAGCATGAGGCCAGGGCCCCAGAACACAGTGCCTGGCAAGGCCTCTGCCCCTGGCCTTTGAGGCAAAGGCCAGCAGCAGATA ACAACCCCGGACAAATCAGCGATGTGTCACCCCCAGTCTCCCACCTTTTCTTCTAATGAGTCGACTTTGAGCTGGAAAGCAGCCGTTTCTCCTTGGTCTAAGTGTGCTGCATGGAGTGAG CAGTAGAAGCCTGCAGCGGCACAAATGCACCTCCCAGTTTGCTGGGTTTATTTTAGAGAATGGGGGTGGGGAGGCAAGAACCAGTGTTTAGCGCGGGACTACTGTTCCAAAAAGAATTCC AACCGACCAGCTTGTTTGTGAAACAAAAAAGTGTTCCCTTTTCAAGTTGAGAACAAAAATTGGGTTTTAAAATTAAAGTATACATTTTTGCATTGCCTTCGGTTTGTATTTAGTGTCTTG AATGTAAGAACATGACCTCCGTGTAGTGTCTGTAATACCTTAGTTTTTTCCACAGATGCTTGTGATTTTTGAACAATACGTGAAAGATGCAAGCACCTGAATTTCTGTTTGAATGCGGAA CCATAGCTGGTTATTTCTCCCTTGTGTTAGTAATAAACGTCTTGCCACAATAAGCCTCCAAAAAAAA |
Protein Sequence | >183 : length: 485 MRKRAPQSEMAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGM HSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLD FTELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLT FQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVAN PLSTA |