| Gene ID | 1398 |
| Symbol | CRK |
| Synonymous | CRKII|p38 |
| Full name | v-crk avian sarcoma virus CT10 oncogene homolog |
| Gene description | adapter molecule crk|proto-oncogene c-Crk |
| Cytoband | 17p13.3 |
| Gene type | protein-coding |
| Synonymous | MIM:164762; HGNC:HGNC:2362; Ensembl:ENSG00000167193; HPRD:01267; Vega:OTTHUMG00000090317 |
Pathways and Diseases | Detail |
|---|---|
Pathway | ARMS-mediated activation;PID Reactome;500631 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | E-cadherin signaling in the nascent adherens junction;PID Curated;200105 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | VEGFR3 signaling in lymphatic endothelium;PID Curated;200188 |
Pathway | PDGFR-alpha signaling pathway;PID Curated;200140 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | p130Cas linkage to MAPK signaling for integrins;PID Reactome;500007 |
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Chronic myeloid leukemia;KEGG PATHWAY;hsa05220 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | EPHB forward signaling;PID Curated;200041 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | Nectin adhesion pathway;PID Curated;200053 |
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | JNK signaling in the CD4+ TCR pathway;PID Curated;200129 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | EPHA forward signaling;PID Curated;200121 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Signaling events mediated by PTP1B;PID Curated;200033 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Signal attenuation;PID Reactome;500505 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | Paxillin-dependent events mediated by a4b1;PID Curated;200117 |
Disease | Gastritis;FunDO |
Disease | Cancer;FunDO |
Disease | Influenza;FunDO |
Sequence Information | |
|---|---|
Nucleotide Sequence | >1398 : length: 3225 ATTTCCGGAGGGGGAGGCCCGCGGCTGCCGCCGCCATTTCGGGCGCTGCTGTGAAGCTGAAACCGGAGCCGGTCCGCTGGGCGGCGGGCGCCGGGGGCCGGAGGGGCGCGCGCGGCGGCG GCACCCCAGCGTTTAGGCGCGGAGGCAGCCATGGCGGGCAACTTCGACTCGGAGGAGCGGAGTAGCTGGTACTGGGGGAGGTTGAGTCGGCAGGAGGCGGTGGCGCTGCTGCAGGGCCAG CGGCACGGGGTGTTCCTGGTGCGGGACTCGAGCACCAGCCCCGGGGACTATGTGCTCAGCGTCTCAGAGAACTCGCGCGTCTCCCACTACATCATCAACAGCAGCGGCCCGCGCCCGCCG GTGCCACCGTCGCCCGCCCAGCCTCCGCCCGGGGTGAGCCCCTCCAGACTCCGAATAGGAGATCAAGAGTTTGATTCATTGCCTGCTTTACTGGAATTCTACAAAATACACTATTTGGAC ACTACAACGTTGATAGAACCAGTTTCCAGATCCAGGCAGGGTAGTGGAGTGATTCTCAGGCAGGAGGAGGCGGAGTATGTGCGAGCCCTCTTTGACTTTAATGGGAATGATGAGGAAGAT CTTCCCTTTAAGAAAGGAGACATCTTGAGAATCCGGGACAAGCCTGAAGAGCAGTGGTGGAATGCGGAGGACAGCGAAGGCAAGAGAGGGATGATTCCAGTCCCTTACGTCGAGAAGTAT AGACCTGCCTCCGCCTCAGTATCGGCTCTGATTGGAGGTAACCAGGAGGGTTCCCACCCACAGCCACTGGGTGGGCCGGAGCCTGGGCCCTATGCCCAACCCAGCGTCAACACTCCGCTC CCTAACCTCCAGAATGGGCCCATATATGCCAGGGTTATCCAGAAGCGAGTCCCCAATGCCTACGACAAGACAGCCTTGGCTTTGGAGGTCGGTGAGCTGGTAAAGGTTACGAAGATTAAT GTGAGTGGTCAGTGGGAAGGGGAGTGTAATGGCAAACGAGGTCACTTCCCATTCACACATGTCCGTCTGCTGGATCAACAGAATCCCGATGAGGACTTCAGCTGAGTATAGTTCAACAGT TTTGCTGACAGATGGGAACAATCTTTTTTTTTTTTTTCCAACTGCCATCTATACAATTTTCTTACAGATGTCAAAAGCAGTCTAGTTTATATAAGCATTCTGTTACCTGTGATATTTTTT AGACTGAACTGCTCCATTCCTAGTCTTAATTACCATATTCAGGGTACGAACTGGAGGGCTTGTGTGTTAGCTTCTGAATTGGCAATTGGAGGCGGTAGTGGTCGTGCCTGTGTGTATCAG AAGGGATAGGTATCTTGCCTCCTTTCTCTCAGGCAGTGCAAATCACCCTGTGGAAAACCGATGGACAGGAAGGAGTGTTACACACTGCTTACCCTGATTTATTCAGTGGTTTTGTTTTCA TTCTGGAACCATACTATCAAATGGCGACAGACTGTTCCGTTCCACCCCCGTGAAGTAATCATGCACCGTGTGAATAGTATCAAGCAGGATTGCTTTCATTGTATGGAGCATGACCAGCGT GTGACTCATTCTGACATTTCAGATCCTAAGAATTCTAAGAACACTACTAGAAGCATTTGTTCCCTCCTAGTCAATGCTTCATACTTTTTCTTGGGATTCTTTTAGCCCTTGACATTCTTG TCCCCCAAACCTGTAAGTAGGTGAATTCCTAAGATAAGTGTGTATTTTCATTCCAGGTGAAAAGCAGGATGTACCGAGCACTTTATTCAGTGCATAGCTTTAAGCCAGTGTTGGATTCAC TAAGTGGACAGCCAGTCTCCCAGCTCTCTGCCTTCCCCAAAAGGGTCGTAGTAGGTCACCCTTCTACAGCAGCTAACTAGAGTCCTAACTAATGGGATCCAGCAGGGCCATTTCTCCAGA GGGCCAGTATCCTATTAGGAGACTCTTGGAATTCTTAGGTTCTACTCAAGAGTGGAAGGACCAATCACCTCTGATATTCTGTGGAAGGTTTTGGGGTCAAATTCTGCCCTCTGCATTCTG TGCAACTTGTATAAAAGTCAAGTTAGTATTACATGAATTTGGGGTAGGGTTAGTGCTTTGAAAAAATGTTGAACCGGCTGGGCGCGGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAG GCCGAGGCGGGTGGATCATGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAACCCCATCTCTGCTAAAGATATAAAAAATTAGCCCGGCGTGGTGGTGCACGCCTGTAATCC CAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTCAACCTGGGAGGTGGAGGCTGCAGTGAGCCGAGATCGCACCACTGCGTTCCAGCCTGAGCGACAGGGCAAGACTCAGTCTCAAAA AAAAAAAAAAGGAAAAAAAAAAGAAAAAAAAATGTTGAACCAATTGTGAATTACTTATGTATTATTCATTTCTCATGGGGAGAGTAATGCTGTTGAAGAACATTACATTGTAAACTGCCT TCATTTTTGGCTCTTTGTTTATGTTCAGGTTTAGTTTACAAACCCATTTAAGTATGGAATGATTTATATGGGGTCAGGTGCTCCACAAAATAGACCTATGAGACCAAAAATGACCTAGGC TATTTAGACGACAGCATGAAACTTCCACGTTAGTTCTCAGTCTATAAAGGCACTTACCGGTCTCTGGTGTGGTATGACCAATAGAAACACCTTATAGTTTGCTTTGGACCTCATTTTGGA AAAATAATCTGCCTTTCTAATTGTTCTGCATAGGTTAAAATGATAAATTTACATTCTTTGAACCTATACCAGATTGTGGTGTCCGAGTGACCGGCACACTGTCTGACACACAGTCAGTGT GCACGTATTTGTCTGAGTGAATGAGGAGACCTGAGAAACCGGTGACGTGGCACAGGGAAGCCAGCTGGCCCAGGATTCCGTACATGGCCGCAAGCAGACTAACGCGTTGACGCTAATTTA ATGTATTTTACCTCACACTAAGGTCATGCTTGATAAAGACGTTAAACTCAACTTGTAAAATGGTAGCCCAGTGCTATGCACAGAGTGGGTGCTCATTAGTGTTGAATGAACACATTTGTA ATACTACATGTAATTCCATCTGACTGCTTTGTTAAATTTTCAGTTAGAACGTAGATACTGTAAAGTCCACACACACATTAAATCTTGTTTTCCTGAAAGTATGGC |
Protein Sequence | >1398 : length: 304 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYA RVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS |