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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

VEGF-165(h) + NP-1(h) <==> VEGF-165(h):NP-1(h) (binding)
VEGF-165(h) + VEGFR-2(h) <==> VEGF-165(h):VEGFR-2(h) (binding)
VEGF-165(h) + NP-1(m) <==> VEGF-165(h):NP-1(m) (binding)
VEGF-165(h) + neuropilin2(h) <==> VEGF-165(h):neuropilin2(h) (binding)
VEGF-165(h) + Abeta42(m.s.) <==> VEGF-165(h):Abeta42(m.s.) (binding)
VEGF-165(h) + ADAMTS-1(h) <==> VEGF-165(h):ADAMTS-1(h) (binding)
VEGF-165(h) --> VEGFR-2(h){pY} (increase of phosphorylation)
VEGF-165(h) --> AKT-1(h){pS473} (increase of phosphorylation)
VEGF-165(h) --> ERK(h){p} (increase of phosphorylation)
VEGF-165(h) --> JNK(h){p} (increase of phosphorylation)
VEGF-165(h) --> FOXO1A(h){pS256} (increase of phosphorylation)
VEGF-165(h) --> p38(h){p} (increase of phosphorylation)
VEGF-165(h) --> Src(h){pY416} (increase of phosphorylation)
VEGF-165(h) --> FAK1(h){pY861}{pY925} (increase of phosphorylation)
VEGF-165(h) --> PLCgamma1(h){p} (increase of phosphorylation)
VEGF-165(h) --> ACE(h) (transactivation)
VEGF-165(h) --> ADAMTS9(h) (transactivation)
VEGF-165(h) --> MGP(h) (transactivation)
VEGF-165(h) --> ESM1(h) (transactivation)
VEGF-165(h) --> HMOX1(h) (transactivation)
VEGF-165(h) --> SOD2(h) (transactivation)
VEGF-165(h) --> INSR(h) (transactivation)
VEGF-165(h) --> Pdgfd(h) (transactivation)
VEGF-165(h) --> PCDH12(h) (transactivation)
VEGF-165(h) --> SELE(h) (transactivation)
VEGF-165(h) --> Vcam1(m) (transactivation)
VEGF-165(h) --> PMCH(h) (transactivation)
VEGF-165(h) --> THBD(h) (transactivation)
VEGF-165(h) --> UBE2J1(h) (transactivation)
VEGF-165(h) --/ ADFP(h) (transrepression)
VEGF-165(h) --/ BTG1(h) (transrepression)
VEGF-165(h) --/ CDKN1B(h) (transrepression)
VEGF-165(h) --/ GADD45A(h) (transrepression)
VEGF-165(h) --/ GADD45B(h) (transrepression)
VEGF-165(h) --/ CASP8(h) (transrepression)
VEGF-165(h) --/ INPP5D(h) (transrepression)
VEGF-165(h) --/ MAP2K7(h) (transrepression)
VEGF-165(h) --/ NFIB(h) (transrepression)
VEGF-165(h) --/ THSD1(h) (transrepression)
VEGF-165(h) --/ TNFRSF1B(h) (transrepression)
VEGF-165(h) --/ TNFSF10(h) (transrepression)
VEGF-165(h) --/ TXNIP(h) (transrepression)
VEGF-165(h) --> BMP2(h) (transactivation)
VEGF-165(h) --> RCAN1(h) (transactivation)
VEGF-165(h) --> PDGFA(h) (transactivation)
VEGF-165(h) --> VEGFC(h) (transactivation)
VEGF-165(h) --> EGR1(h) (transactivation)
VEGF-165(h) --> KLF5(h) (transactivation)
VEGF-165(h) --> ICAM1(h) (transactivation)
VEGF-165(h) --> SERPINE1(h) (transactivation)
VEGF-165(h) --> tPA(h) (transactivation)
VEGF-165(h) --> SPRY4(h) (transactivation)
VEGF-165(h) --> CD55(h) (transactivation)
VEGF-165(h) --> VEGFR-2(h){pY951}{pY1175} (increase of phosphorylation)
VEGFA(h) --> VEGF-165(h) (expression).
RPB7(h) --> VEGF-A(h) (increase of secretion; increase of promoter activity)
brca1(h) --> VEGF-A(h) (increase of secretion)
brca1(h) --> VEGF-A(h) (decrease of secretion)
VEGFA(h) --> VEGF-A(h) (expression).
angiotensin II(h) --> VEGF-A(h) (increase of abundance)
Nod2(m.s.) --> VEGF-A(h) (increase of abundance)
TNF-alpha(h) --> VEGF-A(h) (increase of secretion)
IL-1alpha(h) --> VEGF-A(h) (increase of secretion)
IL-1beta(h) --> VEGF-A(h) (increase of secretion)
IFNgamma(h) --> VEGF-A(h) (decrease of secretion)
TGFbeta1(m.s.) --> VEGF-A(h) (increase of secretion)
TGFbeta2(m.s.) --> VEGF-A(h) (increase of secretion)
HGF(h) --> VEGF-A(h) (increase of abundance)
VEGF-145(h) + neuropilin2(h) <==> VEGF-145(h):neuropilin2(h) (binding)
VEGFA(h) --> VEGF-145(h) (expression).
VEGFA(h) --> VEGF-189(h) (expression).
VEGFA(h) --> VEGF-148(h) (expression).
VEGFA(h) --> VEGF-165b(h) (expression).
VEGFA(h) --> VEGF_1(h) (expression).
VEGFA(h) --> VEGF_2(h) (expression).
VEGFA(h) --> VEGF_3(h) (expression).
VEGFA(h) --> VEGF_4(h) (expression).
VEGFA(h) --> VEGF_5(h) (expression).
VEGFA(h) --> VEGF_6(h) (expression).
hsa-miR-125a --/ VEGF_6(h) (translational repression).
hsa-miR-93 --/ VEGF_6(h) (translational repression).
hsa-miR-302d --/ VEGF_6(h) (translational repression).
hsa-miR-373 --/ VEGF_6(h) (translational repression).
hsa-miR-378 --/ VEGF_6(h) (translational repression).
hsa-miR-16 --/ VEGF_6(h) (translational repression).
VEGFA(h) --> VEGF_7(h) (expression).
VEGFA(h) --> VEGF-206(h) (expression).
VEGFA(h) --> VEGF-183(h) (expression).

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