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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

TGFalpha(h) + ErbB2(m.s.):ErbB4(m) <==> TGFalpha(h):ErbB2(m.s.):ErbB4(m) (binding)
TGFalpha(h) + (ErbB1(m.s.))2 <==> TGFalpha(h):(ErbB1(m.s.))2 (binding)
TGFalpha(h) + ErbB1(m.s.):ErbB2(m.s.) <==> TGFalpha(h):ErbB2(m.s.):ErbB1(m.s.) (binding)
TGFalpha(h) --TACE(m)--> TGFalpha-ECD(h) + protein remnants (processing)
TGFalpha(h) --> ERK1(h){p} (increase of phosphorylation)
TGFalpha(h) --> ERK2(h){p} (increase of phosphorylation)
TGFA(h) --> TGFalpha(h) (expression).
TNF-alpha{sol}(h) --> TGFalpha(h) (increase of secretion)
NT(m.s.) --> TGFalpha(h) (increase of secretion)
TGFalpha(h) + MAGI-3(m) <==> TGFalpha(h):MAGI-3(m) (binding)
TGFalpha(h) + MAGI-3-isoform2(m) <==> TGFalpha(h):MAGI-3-isoform2(m) (binding)
TGFalpha(h) + MAGI-2(h) <==> TGFalpha(h):MAGI-2(h) (binding)
TGFalpha(h) --> SRCASM(h){pY} (increase of phosphorylation)
TGFalpha(h) --> ErbB1(h){pY} (increase of phosphorylation)
TGFalpha(h) --> ERK(h){p} (increase of phosphorylation)
TGFalpha(h) --/ RANTES(h) (decrease of abundance)
TGFalpha(h) --/ IL-8(h) (decrease of abundance)
TGFalpha(h) --> s100a11(h) (increase of abundance)
TGFalpha(h) --> TLR5(h) (transactivation)
TGFalpha(h) --> TLR9(h) (transactivation)
TGFalpha(h) --> IL-8(h) (increase of secretion)
TGFalpha(h) --> Beta-defensin2(h) (increase of secretion)
TGFalpha(h) --> DEFB4(h) (transactivation; transactivation)
TGFalpha(h) --> PrPc(h) (increase of abundance)
TGFA(h) --> TGFalpha(h) (expression).

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top