| H-Ras(h):GTP:NO + Raf-1(h) <==> H-Ras(h):GTP:NO:Raf-1(h) (binding)
|
bag1(m) + Bcl-2(h) + Raf-1(h) <==> bag1(m):Bcl-2(h):Raf-1(h) (binding)
|
14-3-3epsilon(h) + Raf-1(h) <==> 14-3-3epsilon(h):Raf-1(h) (binding)
|
Cdc25A(h) + 14-3-3beta(h) + Raf-1(h) <==> Cdc25A(h):14-3-3beta(h):Raf-1(h) (binding)
|
Raf-1(h) + Cdc25A(h) <==> Raf-1(h):Cdc25A(h) (binding)
|
Raf-1(h) + Cdc25B(h) <==> Raf-1(h):Cdc25B(h) (binding)
|
Raf-1(h) + ATP --PAK3(r)--> Raf-1(h){pS338} + ADP (phosphorylation)
|
Raf-1(h) + ATP --PAK3a(m)--> Raf-1(h){pS338} + ADP (phosphorylation)
|
Raf-1(h) + 3 ATP --PKAc(m)--> Raf-1(h){pS43}{pS259}{pS621} + 3 ADP (phosphorylation)
|
Raf-1(h) + MEK1(r) <==> Raf-1(h):MEK1(r) (binding)
|
Raf-1(h) + 2 ATP --PKC(r)--> Raf-1(h){pS497}{pS619} + 2 ADP (phosphorylation)
|
Src(c) + Raf-1(h) <==> Src(c):Raf-1(h) (binding)
|
Raf-1(h) + 14-3-3zeta(b) <==> Raf-1(h):14-3-3zeta(b) (binding)
|
H-Ras(h):GTP + Raf-1(h) <==> H-Ras(h):GTP:Raf-1(h) (binding; translocation)
|
FasL(h):Fas(h):FADD(h):proCaspase-8(h):c-FLIP-L-p43(h) + Raf-1(h) <==> c-FLIP-L-p43(h):FADD(h):Fas(h):FasL(h):proCaspase-8(h):Raf-1(h) (binding)
|
Raf-1(h) + pRb(h) <==> Raf-1(h):pRb(h) (binding)
|
Raf-1(h) + p130(h) <==> Raf-1(h):p130(h) (binding)
|
E2F(h):DP(h) + pRb(h) + Raf-1(h) <==> E2F(h):DP(h):pRb(h):Raf-1(h) (binding)
|
Raf-1(h) + MEK2(m) <==> Raf-1(h):MEK2(m) (binding)
|
Raf-1(h) + ATP --KSR(m)--> Raf-1(h){pT269} + ADP (phosphorylation)
|
Raf-1(h) + MEK2(h) <==> Raf-1(h):MEK2(h) (binding)
|
Raf-1(h) + MEK1(m) <==> Raf-1(h):MEK1(m) (binding)
|
Raf-1(h) + ATP --PKCalpha(h)--> Raf-1(h){pS499} + ADP (phosphorylation)
|
Raf-1(h) + ATP --PKCbeta(h)--> Raf-1(h){p} + ADP (phosphorylation)
|
Raf-1(h) + ATP --PKCgamma(r)--> Raf-1(h){p} + ADP (phosphorylation)
|
14-3-3eta(h) + Raf-1(h) <==> 14-3-3eta(h):Raf-1(h) (binding)
|
14-3-3zeta(h) + Raf-1(h) <==> 14-3-3zeta(h):Raf-1(h) (binding)
|
A20(h) + 14-3-3(h) + Raf-1(h) <==> A20(h):14-3-3(h):Raf-1(h) (binding)
|
G-beta-1(v.s.):G-gamma-2(v.s.) + Raf-1(h) <==> G-beta-1(v.s.):G-gamma-2(v.s.):Raf-1(h) (binding)
|
angiotensin II(m.s.):AT1A(r){p} + beta-arrestin2(h) + ERK2(r) + MEK1(v.s.) + Raf-1(h) <==> angiotensin II(m.s.):AT1A(r){p}:beta-arrestin2(h):Raf-1(h):MEK1(v.s.):ERK2(r) (binding)
|
p65PAK(h){pT423} + Raf-1(h) <==> p65PAK(h){pT423}:Raf-1(h) (binding)
|
Raf-1(h) + RKIP(r) <==> Raf-1(h):RKIP(r) (binding)
|
Raf-1(h) + MEK1(h) <==> Raf-1(h):MEK1(h) (binding)
|
Raf-1(h) + H-Ras(h) <==> Raf-1(h):H-Ras(h) (binding)
|
Raf-1(h) + MEK1(m.s.) <==> Raf-1(h):MEK1(m.s.) (binding)
|
Raf-1(h) + Cnk1(h) <==> Raf-1(h):Cnk1(h) (binding)
|
Raf-1(h) + ATP --> Raf-1(h){pY} + ADP (phosphorylation)
|
PDK1(h) + MEK1(r) + Raf-1(h) <==> PDK1(h):MEK1(r):Raf-1(h) (binding)
|
MEK1(h) + Raf-1(h) <==> MEK1(h):Raf-1(h) (binding)
|
Raf-1(h) --> RSK(h){pT573} (increase of phosphorylation)
|
Raf-1(h) --> MAPK(h){pT202}{pY204} (increase of phosphorylation)
|
Raf-1(h) + Grb10zeta(h) <==> Raf-1(h):Grb10zeta(h) (binding)
|
H-Ras(m.s.):GTP + Raf-1(h) <==> H-Ras(m.s.):GTP:Raf-1(h) (binding)
|
Raf-1(h) + ATP --p65PAK(h)--> Raf-1(h){pS338} + ADP (phosphorylation)
|
Raf-1(h) + ATP --Src(m.s.)--> Raf-1(h){pY340} + ADP (phosphorylation)
|
Raf-1(h) + Bcl-2(h) <==> Raf-1(h):Bcl-2(h) (binding)
|
HCV-NS5A(HCV) + Raf-1(h) <==> HCV-NS5A(HCV):Raf-1(h) (binding)
|
Raf-1(h) --> Raf-1(h) (translocation)
|
Raf-1(h) + ATP --> Raf-1(h){pS338} + ADP (phosphorylation)
|
Raf-1(h) + ATP --> Raf-1(h) + ADP (phosphorylation; automodification)
|
14-3-3tau(h) + Raf-1(h) <==> 14-3-3tau(h):Raf-1(h) (binding)
|
14-3-3gamma(h) + Raf-1(h) <==> 14-3-3gamma(h):Raf-1(h) (binding)
|
14-3-3sigma(m.s.) + Raf-1(h) <==> 14-3-3sigma(m.s.):Raf-1(h) (binding)
|
Ras(h):GTP + Raf-1(h) <==> Ras(h):GTP:Raf-1(h) (binding)
|
bag1(m) --> Raf-1(h) (activation)
|
RAF1(h) --> Raf-1(h) (expression).
|
Raf-1(h):Cdc25B(h) + ATP --> Raf-1(h) + Cdc25B(h){p} + ADP (phosphorylation; dissociation)
|
Raf-1(h):Cdc25A(h) + ATP --> Raf-1(h) + Cdc25A(h){p} + ADP (phosphorylation; dissociation)
|
Raf-1(h):MEK1(r) + ATP --> Raf-1(h) + MEK1(r){p} + ADP (phosphorylation; dissociation)
|
Raf-1(h):pRb(h) + ATP --> Raf-1(h) + pRb(h){p} + ADP (phosphorylation; dissociation)
|
Fas(h) --> Raf-1(h) (binding)
|
c-FLIP(m) --> Raf-1(h) (binding)
|
TRAF1(h) --> Raf-1(h) (binding)
|
TRAF2(h) --> Raf-1(h) (binding)
|
Raf-1(h) --> Raf-1(h) (translocation)
|
Raf-1(h) + ATP --> Raf-1(h) + ADP (phosphorylation; automodification)
|
bad(h) + ATP --Raf-1(h)--> bad(h){pS} + ADP (phosphorylation)
|
MEK(h) + ATP --Raf-1(h)--> MEK(h){pS} + ADP (phosphorylation)
|
MEK1(r) + 2 ATP --Raf-1(h)--> MEK1(r){pS218}{pS222} + 2 ADP (phosphorylation)
|
ERK(m.s.) + ATP --Raf-1(h)--> ERK(m.s.){p} + ADP (phosphorylation)
|
MEK(m.s.) + ATP --Raf-1(h)--> MEK(m.s.){p} + ADP (phosphorylation)
|
bad(m.s.) + ATP --Raf-1(h)--> bad(m.s.){pS112} + ADP (phosphorylation)
|
MEK1(m.s.) + ATP --Raf-1(h)--> MEK1(m.s.){p} + ADP (phosphorylation)
|
Raf-1(h) + Hsp50(r) <==> Raf-1(h):Hsp50(r) (binding)
|
Ras(r):GTP + Raf-1(h) <==> Ras(r):GTP:Raf-1(h) (binding)
|
Raf-1(h) --> CDKN2B(m) (transactivation)
|
Raf-1(h) --> CDKN2A(m) (transactivation)
|
Raf-1(h) + Ras(h):GTP <==> Raf-1(h):Ras(h):GTP (binding)
|
RAF1(h) --> Raf-1(h) (expression).
|
