| p120CAS 3A(h){pY} + SHP-1(h) <==> p120CAS 3A(h){pY}:SHP-1(h) (binding)
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ROS(m){pY} + SHP-1(h) <==> ROS(m){pY}:SHP-1(h) (binding)
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c-Kit(m){pY569} + SHP-1(h) <==> c-Kit(m){pY569}:SHP-1(h) (binding)
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IL-4Ralpha(h) + SHP-1(h) <==> IL-4Ralpha(h):SHP-1(h) (binding)
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SHP-1(h) + p85(h) <==> SHP-1(h):p85(h) (binding)
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EpoR(m){pY429} + SHP-1(h) <==> EpoR(m){pY429}:SHP-1(h) (binding)
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FcgammaRIIB(m){pY309} + SHP-1(h) <==> FcgammaRIIB(m){pY309}:SHP-1(h) (binding)
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CD22(h){pY} + SHP-1(h) <==> CD22(h){pY}:SHP-1(h) (binding)
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CD22(h){pY} + Syk(h){pY} + SHP-1(h) <==> CD22(h){pY}:Syk(h){pY}:SHP-1(h) (binding)
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Syk(h){pY} + CD22(h){pY} + SHP-1(h) + PLCgamma1(h) <==> Syk(h){pY}:CD22(h){pY}:SHP-1(h):PLCgamma1(h) (binding)
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SHP-1(h) --> p120CAS(h) (decrease of phosphorylation)
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SHP-1(h) + NKAT1(h){p} + NTP --> SHP-1(h){pY}:NKAT1(h){p} + NDP (phosphorylation; binding)
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Abl(m.s.) + SHP-1(h) + NTP --> Abl(m.s.):SHP-1(h){pY}{pY536} + NDP (phosphorylation; binding)
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SHP-1(h) + Pyk2(h) <==> SHP-1(h):Pyk2(h) (binding)
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SHP-1(h) --> Syk(h) (binding)
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SHP-1(h) --> PLCgamma1(h) (binding)
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beta-catenin(h){p} + SHP-1(h) --> SHP-1(h):beta-catenin(h) + p (dephosphorylation; binding)
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SHP-1(h) + MCP(h) <==> SHP-1(h):MCP(h) (binding)
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SHP-1(h) + caveolin-1(h) <==> SHP-1(h):caveolin-1(h) (binding)
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Ret(m.s.){p} + SHP-1(h) <==> Ret(m.s.){p}:SHP-1(h) (binding)
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Ret(h) + SHP-1(h) <==> Ret(h):SHP-1(h) (binding)
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SHP-1(h) --> alpha-actinin-1(h) (decrease of phosphorylation)
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SHP-1(h) + LAT(h) <==> SHP-1(h):LAT(h) (binding)
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LAIR1(h) + SHP-1(h) <==> LAIR1(h):SHP-1(h) (binding)
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LAIR1(h){pY233}{pY263} + SHP-1(h) <==> LAIR1(h){pY233}{pY263}:SHP-1(h) (binding)
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PKCalpha(h) + SHP-1(h) <==> PKCalpha(h):SHP-1(h) (binding)
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Vav(h) + SHP-1(h) <==> Vav(h):SHP-1(h) (binding)
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SHP-1(h) --> SHP-1(h) (translocation)
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SHP-1(h) + KLRD1(h):NKG2-A(h){pY} <==> SHP-1(h):KLRD1(h):NKG2-A(h){pY} (binding)
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ErbB1-p170(h){pY998} + SHP-1(h) <==> ErbB1-p170(h){pY998}:SHP-1(h) (binding)
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ErbB2(h){pY1023}{pY1222} + SHP-1(h) <==> ErbB2(h){pY1023}{pY1222}:SHP-1(h) (binding)
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SHP-1(h) + ErbB1(h){pY} <==> SHP-1(h):ErbB1(h){pY} (binding)
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SHP-1(h) + LAIR(h) <==> SHP-1(h):LAIR(h) (binding)
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CD244(m.s.){pY} + SHP-1(h) <==> CD244(m.s.){pY}:SHP-1(h) (binding)
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BTLA1(h) + SHP-1(h) <==> BTLA1(h):SHP-1(h) (binding)
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SHP-1(h) + CD244(h) <==> SHP-1(h):CD244(h) (binding)
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IRp60(h) + SHP-1(h) <==> IRp60(h):SHP-1(h) (binding)
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SHP-1(h) --/ IGF1(h) (transrepression)
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UV --/ SHP-1(h) (inhibition)
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ROS(m):SHP-1(h) <==> ROS(m) + SHP-1(h) (dissociation)
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PTPN6(h) --> SHP-1(h) (expression).
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CD22(h){pY} --> SHP-1(h) (binding)
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SHP-1(h) --> SHP-1(h) (translocation)
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ErbB1(h){pY} --SHP-1(h)--> ErbB1(h) + p (dephosphorylation)
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GHR(rb){pY} --SHP-1(h)--> GHR(rb) + p (dephosphorylation)
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SHP1-isoform1(h) + ATP --PKCalpha(h)--> SHP1-isoform1(h){pS591} + ADP (phosphorylation)
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SHP1-isoform1(h) + ATP --PKC(h)--> SHP1-isoform1(h){pS591} + ADP (phosphorylation)
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SHP1-isoform1(h) + ATP --> SHP1-isoform1(h){pY} + ADP (phosphorylation)
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SHP1-isoform1(h) + PKCalpha(h) <==> SHP1-isoform1(h):PKCalpha(h) (binding)
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SHP1-isoform1(h) + ATP --> SHP1-isoform1(h){pY564} + ADP (phosphorylation)
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PTPN6(h) --> SHP1-isoform1(h) (expression).
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Cd72(m){pY} --SHP1-isoform1(h)--> Cd72(m) + p (dephosphorylation)
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ZAP-70(h){pY} --SHP1-isoform1(h)--> ZAP-70(h) + p (dephosphorylation)
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SHP1-isoform2(h) + ErbB1(h) <==> SHP1-isoform2(h):ErbB1(h) (binding)
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ErbB1-p170(h){pY1197} + SHP1-isoform2(h) <==> SHP1-isoform2(h):ErbB1-p170(h){pY1197} (binding)
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SHP1-isoform2(h) + ErbB1(h){pY} <==> SHP1-isoform2(h):ErbB1(h){pY} (binding)
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PTPN6(h) --> SHP1-isoform2(h) (expression).
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ErbB1(h){pY} --SHP1-isoform2(h)--> ErbB1(h) + p (dephosphorylation)
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PTPN6(h) --> SHP1-isoform3(h) (expression).
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PTPN6(h) --> SHP-1L(h) (expression).
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ZAP-70(h){pY} --SHP-1L(h)--> ZAP-70(h) + p (dephosphorylation)
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