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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

FAK1(h) + paxillin(h) <==> FAK1(h):paxillin(h) (binding)
FAK1(h) + Cas(h) <==> FAK1(h):Cas(h) (binding)
FAK1(h) + vinculin(h) <==> FAK1(h):vinculin(h) (binding)
FAK1(h) --Caspase-3(h)--> protein remnants (processing)
FAK1(h) --Caspase-7(h)--> protein remnants (processing)
FAK1(h) + NTP --Src(v.s.)--> FAK1(h){pY} + NDP (phosphorylation)
FAK1(h) + NTP --Fyn(m)--> FAK1(h){pY} + NDP (phosphorylation)
FAK1(h) + NTP --Yes(v.s.)--> FAK1(h){pY} + NDP (phosphorylation)
FAK1(h) + NTP --Pyk2(r){pY402}{pY579}{pY580}--> FAK1(h){pY} + NDP (phosphorylation)
FAK1(h) + HEF1(h) <==> FAK1(h):HEF1(h) (binding)
alpha IIb-integrin(h):beta3-integrin(h) + FAK1(h) <==> alpha IIb-integrin(h):beta3-integrin(h):FAK1(h) (binding)
FAK1(h) + ATP --> FAK1(h){pY397} + ADP (phosphorylation)
FAK1(h) + ATP --> FAK1(h){p} + ADP (phosphorylation)
Bmx(m.s.) + FAK1(h) <==> Bmx(m.s.):FAK1(h) (binding)
FAK1(h) + LMW-PTP(h) <==> FAK1(h):LMW-PTP(h) (binding)
FAK1(h) + n ubiquitin(h) --> FAK1(h){ub(n)} (ubiquitination)
FAK1(h) + ATP --> FAK1(h){pY} + ADP (phosphorylation)
FAK1(h) + 4 ATP --> FAK1(h){pY397}{pY577}{pY861}{pY925} + 4 ADP (phosphorylation)
p85(h) + FAK1(h) <==> p85(h):FAK1(h) (binding)
FAK1(h) + SOCS-2(h) <==> FAK1(h):SOCS-2(h) (binding)
FAK1(h) + APG12(h) <==> FAK1(h):APG12(h) (binding)
FAK1(h) + ATP --> FAK1(h){pY576} + ADP (phosphorylation)
ErbB2(m.s.) + FAK1(h) <==> ErbB2(m.s.):FAK1(h) (binding)
FAK1(h) + beta1-integrin(h) <==> FAK1(h):beta1-integrin(h) (binding)
FAK1(h) + 2 ATP --> FAK1(h){pY861}{pY925} + 2 ADP (phosphorylation)
FAK1(h) + ATP --> FAK1(h){pY861} + ADP (phosphorylation)
PTK2(h) --> FAK1(h) (expression).
FAK1(h){pY} --LMW-PTP(h)--> FAK1(h) + p (dephosphorylation)
p53(m.s.) --/ FAK1(h) (decrease of abundance)
Cas(mo) + ATP --FAK1(h)--> Cas(mo){pY} + ADP (phosphorylation)
PTK2(h) --> FAK1-Isoform-1(h) (expression).
PTK2(h) --> FAK1-isoform-2(h) (expression).
PTK2(h) --> FAK1-isoform-3(h) (expression).
PTK2(h) --> FAK1-isoform-4(h) (expression).

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top