| Smac(h) + cIAP-1(h) <==> Smac(h):cIAP-1(h) (binding)
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Smac(h) + cIAP-2(h) <==> Smac(h):cIAP-2(h) (binding)
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Smac(h) + XIAP(h) <==> Smac(h):XIAP(h) (binding)
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Smac(h) + survivin(h) <==> Smac(h):survivin(h) (binding)
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Smac(h) + ML-IAP(h) <==> Smac(h):ML-IAP(h) (binding)
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Smac(h) + ML-IAP1(h) <==> Smac(h):ML-IAP1(h) (binding)
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Smac(h) + ML-IAP2(h) <==> Smac(h):ML-IAP2(h) (binding)
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Smac(h) + NADE(m) <==> Smac(h):NADE(m) (binding)
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Smac(h) + n ubiquitin(v.s.) --XIAP(h)--> Smac(h){ub(n)} (ubiquitination)
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Smac(h) --> Smac(h) (translocation)
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XIAP(h) + Smac(h) <==> XIAP(h):Smac(h) (binding)
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Smac(h) --> Caspase-9-p35(h) (increase of processing)
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apollon(h) + Smac(h) <==> apollon(h):Smac(h) (binding)
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Smac(h) + apollon(m) <==> Smac(h):apollon(m) (binding)
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Smac(h) + ubiquitin(h) --apollon(m),E1(h)--> Smac(h){ub} (ubiquitination)
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Smac(h) --> Caspase-3(h):apollon(m) (decrease of binding)
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Smac(h) --> Caspase-9(h):apollon(m) (decrease of binding)
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XIAP(m.s.) + Smac(h) <==> XIAP(m.s.):Smac(h) (binding)
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Smac(h) --> Caspase-7(h):apollon(m) (decrease of binding)
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DIABLO(h) --> Smac(h) (expression).
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Smac(h) --> Smac(h) (translocation)
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p75NTR(m.s.) --> Smac(h) (increase of abundance)
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Smac-alpha(h) + XIAP(h) <==> Smac-alpha(h):XIAP(h) (binding)
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Smac-alpha(h) + XIAP(m.s.) <==> Smac-alpha(h):XIAP(m.s.) (binding)
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DIABLO(h) --> Smac-alpha(h) (expression).
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Caspase-7(h) + n ubiquitin(h) --XIAP(h)--> Caspase-7(h){ub(n)} (ubiquitination)
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cIAP-2(h) + n ubiquitin(h) --> cIAP-2(h){ub(n)} (ubiquitination)
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DIABLO(h) --> Smac-beta(h) (expression).
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Smac-delta(h) + XIAP(h) <==> Smac-delta(h):XIAP(h) (binding)
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Smac-delta(h) --> Smac-delta(h) (translocation)
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Smac-delta(h) + XIAP(m.s.) <==> Smac-delta(h):XIAP(m.s.) (binding)
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Smac-delta(h) --/ XIAP(m.s.) (decrease of abundance)
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Smac-delta(h) --> XIAP(m.s.) (increase of cleavage)
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Smac-delta(h) --> XIAP(m.s.){ub}n (increase of ubiquitination)
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Smac-delta(h) --/ XIAP(m) (decrease of abundance)
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Smac-delta(h) --> XIAP(m.s.):Caspase-9-p35(h) (decrease of binding)
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Smac-delta(h) --> XIAP(m.s.):Caspase-9-p12(h) (decrease of binding)
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Smac-delta(h) --> proCaspase-3(h) (increase of processing)
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DIABLO(h) --> Smac-delta(h) (expression).
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Smac-delta(h) --> Smac-delta(h) (translocation)
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Caspase-7(h) + n ubiquitin(h) --XIAP(h)--> Caspase-7(h){ub(n)} (ubiquitination)
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cIAP-2(h) + n ubiquitin(h) --> cIAP-2(h){ub(n)} (ubiquitination)
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