| MEK1(h) + ATP --H-Ras(h):GTP:NO:Raf-1(h)--> MEK1(h){p} + ADP (phosphorylation)
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Raf-1(h) + MEK1(h) <==> Raf-1(h):MEK1(h) (binding)
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MEK1(h) + ATP --> MEK1(h){p} + ADP (phosphorylation)
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MEK1(h) + ATP --Lck(m.s.)--> MEK1(h){pY} + ADP (phosphorylation)
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MEK1(h) + Raf-1(h) <==> MEK1(h):Raf-1(h) (binding)
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Grb10zeta(h) + MEK1(h) <==> Grb10zeta(h):MEK1(h) (binding)
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MEK1(h) --> E47(h){p} (increase of phosphorylation)
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MEK1(h) --> E47(m){p} (increase of phosphorylation)
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MEK1(h) --/ E47(h) (decrease of abundance)
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MEK1(h) --> E47(h){p}:Skp2(h) (increase of binding)
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MEK1(h) --> BIRC3(h) (transactivation)
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MEK1(h) --> MICA(h) (increase of abundance)
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MEK1(h) + PPARgamma(h) <==> MEK1(h):PPARgamma(h) (binding)
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MEK1(h) + ATP --> MEK1(h){pS} + ADP (phosphorylation)
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MEK1(h) --/ NOTCH1(h) (transrepression)
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MAP2K1(h) --> MEK1(h) (expression).
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CSE1(h) + ATP --MEK1(h)--> CSE1(h){pY} + ADP (phosphorylation)
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ERK1(m) + ATP --MEK1(h)--> ERK1(m){p} + ADP (phosphorylation)
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ERK2(m) + ATP --MEK1(h)--> ERK2(m){p} + ADP (phosphorylation)
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ERK1(h) + ATP --MEK1(h)--> ERK1(h){p} + ADP (phosphorylation)
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ERK2(h) + ATP --MEK1(h)--> ERK2(h){p} + ADP (phosphorylation)
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MEK1(h) + 2 ATP --> MEK1(h){pS218}{pS222} + 2 ADP (phosphorylation)
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MEK1(h) + ATP --Cot(h){p}--> MEK1(h){p} + ADP (phosphorylation)
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MEK1(h) + PPARgamma1(m.s.) <==> MEK1(h):PPARgamma1(m.s.) (binding)
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MEK1(h) + PPARgamma1(h) <==> MEK1(h):PPARgamma1(h) (binding)
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MEK1(h) + PPARgamma(m.s.) <==> MEK1(h):PPARgamma(m.s.) (binding)
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MEK1(h) + ATP --Cdk5(h)--> MEK1(h){p} + ADP (phosphorylation)
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ERK2(r) + MEK1(h) <==> ERK2(r):MEK1(h) (binding)
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ERK1(h) + MEK1(h) <==> ERK1(h):MEK1(h) (binding)
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ERK2(r) + MEK1(h) <==> ERK2(r):MEK1(h) (binding)
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MAP2K1(h) --> MEK1(h) (expression).
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HCV-NS5A(HCV) + ATP --MEK1(h)--> HCV-NS5A(HCV){p} + ADP (phosphorylation)
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ERK2(r) + ATP --MEK1(h)--> ERK2(r){p} + ADP (phosphorylation)
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