| IL-22(h) --> STAT3(h) (activation; phosphorylation)
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IL-22(h) --> STAT1(h) (activation; phosphorylation)
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IL-22(h) + IL-10R2(h) <==> IL-22(h):IL-10R2(h) (binding)
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IL-22(h) --> STAT5(h) (activation; phosphorylation)
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IL-22(h) + IL-22BP(h) <==> IL-22(h):IL-22BP(h) (binding)
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IL-22(h) + IL-22R1(h) <==> IL-22(h):IL-22R1(h) (binding)
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IL-22(h) + IL-22R1(h) + IL-10R2(h) <==> IL-22(h):IL-22R1(h):IL-10R2(h) (binding)
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IL-22(h) --> Jak1(r){pY} (activation; phosphorylation)
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IL-22(h) --> Tyk2(r){pY} (activation; phosphorylation)
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IL22(h) --> IL-22(h) (expression).
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IL-22(h) --> NOS2(h) (transactivation)
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IL-22(h) + IL-10R2(h) <==> IL-22(h):IL-10R2(h) (binding)
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IL-22R1(h) + IL-22(h) <==> IL-22R1(h):IL-22(h) (binding)
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IL-10R2(m.s.) + IL-22R1(h) + IL-22(h) <==> IL-10R2(m.s.):IL-22R1(h):IL-22(h) (binding)
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IL-22(h) --> STAT1(h){pY701} (increase of phosphorylation)
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IL-22(h) --> STAT3(h){pY705} (increase of phosphorylation)
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IL-22(h) --> STAT5(h){pY} (increase of phosphorylation)
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IL-22(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation)
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IL-22(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation)
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IL-22(h) --> AKT(h){p} (increase of phosphorylation)
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IL-22(h) --> IL6(h) (transactivation)
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IL-22(h) --> IL8(h) (transactivation)
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IL-22(h) --> TNF(h) (transactivation)
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IL-22(h) --> SOCS3(h) (transactivation)
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IL-22(h) --> IL-8(h) (increase of abundance)
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IL-22(h) --> STAT1(m){pY} (increase of phosphorylation)
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IL-22(h) --> STAT3(m){pY705} (increase of phosphorylation)
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IL-22(h) --> STAT5(m){pY} (increase of phosphorylation)
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2 IL-22(h) <==> (IL-22(h))2 (binding)
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4 IL-22(h) <==> (IL-22(h))4 (binding)
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IL-22(h) + IL-22BP-isoform2(h) <==> IL-22(h):IL-22BP-isoform2(h) (binding)
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IL22(h) --> IL-22(h) (expression).
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