| SARA(h) + Smad2-L(h) <==> SARA(h):Smad2-L(h) (binding)
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Smad2-L(h) --TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h)--> Smad2-L(h){p} (phosphorylation)
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Smad2-L(h) + NTP --TGFbetaR-I(h)--> Smad2-L(h){p} + NDP (phosphorylation)
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Smad2-L(h) + smad4(h) --TGFbetaR-I(h)--> Smad2-L(h):smad4(h) (binding)
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Smad2-L(h) + Smad3(h) --TGFbetaR-I(h)--> Smad2-L(h):Smad3(h) (binding)
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Smad2-L(h) + Smurf-2(h) <==> Smad2-L(h):Smurf-2(h) (binding)
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Smad2-L(h) + n ubiquitin(h) --Smurf-2(h)--> Smad2-L(h){ub(n)} (ubiquitination)
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Smad2-L(h) + SARA(h) + HRS(m) <==> Smad2-L(h):SARA(h):HRS(m) (binding)
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Smad2-L(h) + NTP --CaMKII-alpha(r)--> Smad2-L(h){p} + NDP (phosphorylation)
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Smad2-L(h) + Smad3(h) --TGFbetaR-I(h)--> Smad2-L(h):Smad3(h) (binding)
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Smad2-L(h) + smad4(h) --TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h)--> Smad2-L(h):smad4(h) (binding)
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Smad2-L(h) + Smad3(h) --TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h)--> Smad2-L(h):Smad3(h) (binding)
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TGFbetaR-II(h) + TGFbetaR-I(h) + Smad2-L(h) <==> TGFbetaR-II(h):TGFbetaR-I(h):Smad2-L(h) (binding)
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Smad2-L(h) + NTP --TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h)--> Smad2-L(h){p} + NDP (phosphorylation)
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Smad2-L(h) + ATP --TGFbetaR-I(h)--> Smad2-L(h){p} + ADP (phosphorylation)
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p300(h) + Smad2-L(h) <==> p300(h):Smad2-L(h) (binding).
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Smad2-L(h) + TGIF(h) <==> Smad2-L(h):TGIF(h) (binding).
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FOXH1(m) + Smad2-L(h) <==> FOXH1(m):Smad2-L(h) (binding).
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SKIP(h) + Smad2-L(h) <==> SKIP(h):Smad2-L(h) (binding).
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p62Dok-1(m) + Smad2-L(h) <==> p62Dok-1(m):Smad2-L(h) (binding)
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CBP(m) + Smad2-L(h) <==> CBP(m):Smad2-L(h) (binding)
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Smad2-L(h) + 5 ATP --ERK1(h)--> Smad2-L(h){pT8}{pT220}{pS245}{pS250}{pS255} + 5 ADP (phosphorylation)
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Smad2-L(h) + 5 ATP --> Smad2-L(h){pT8}{pT220}{pS245}{pS250}{pS255} + 5 ADP (phosphorylation)
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Smad2-L(h) + smad4(h) <==> Smad2-L(h):smad4(h) (binding)
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Smad2-L(h) + calmodulin(m) <==> Smad2-L(h):calmodulin(m) (binding)
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TGFbeta1(h) --> Smad2-L(h) (activation; phosphorylation)
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SMAD2(h) --> Smad2-L(h) (expression).
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calmodulin(m) --/ Smad2-L(h) (decrease of abundance)
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SMAD2(h) --> Smad2 (437 AA)(h) (expression).
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Sox9(r) + Smad2(h) <==> Sox9(r):Smad2(h) (binding)
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c-Myc(h) + Smad2(h) <==> c-Myc(h):Smad2(h) (binding)
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smad4(h) + Smad2(h) <==> smad4(h):Smad2(h) (binding)
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c-Myc(m.s.) + Smad2(h) <==> c-Myc(m.s.):Smad2(h) (binding)
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Smad2(h) + p53(h) <==> Smad2(h):p53(h) (binding)
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Smad2(h) --> collagen-IIalpha1(h) (increase of abundance)
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Smad2(h) + ATP --> Smad2(h){p} + ADP (phosphorylation)
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Smad2(h) + Dab2(h) <==> Smad2(h):Dab2(h) (binding)
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Smad2(h) + ATP --> Smad2(h){pS} + ADP (phosphorylation)
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Smad2(h) + PDK1(h) <==> Smad2(h):PDK1(h) (binding)
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Smad2(h) + acetyl-CoA --> Smad2(h){aceK} + CoA (acetylation)
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Smad2(h) + acetyl-CoA --p300(m.s.)--> Smad2(h){aceK} + CoA (acetylation)
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Smad2(h) --> TGFB2(h) (DNA binding).
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Smad2(h) --> FBLN5(h) (DNA binding).
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Smad2(h) --> TNC(h) (DNA binding).
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Smad2(h) --> MMP13(h) (DNA binding).
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Smad2(h) --> ACTA2(h) (DNA binding).
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Smad2(h) + 2 ATP --> Smad2(h){pS465}{pS467} + 2 ADP (phosphorylation)
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c-Ski(h) + Smad2(h) + Smad4(h) <==> c-Ski(h):Smad2(h):Smad4(h) (binding)
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Smad2(h) --> c-myc(h) (DNA binding).
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Smad2(h) + 2 ATP --> Smad2(h){pS}2 + 2 ADP (phosphorylation)
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SMAD2(h) --> Smad2(h) (expression).
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CHIP(h) --/ Smad2(h) (decrease of abundance)
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SRC3(h) --> Smad2(h) (increase of abundance)
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SMAD2(h) --> Smad2-S(h) (expression).
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