| c-Kit(h) + Jak2(h) <==> c-Kit(h):Jak2(h) (binding)
|
Jak2(h) + ATP --> Jak2(h){pY} + ADP (phosphorylation)
|
Jak2(h) + STAM(h) <==> Jak2(h):STAM(h) (binding)
|
IL-4Ralpha(h) + Jak2(h) <==> IL-4Ralpha(h):Jak2(h) (binding)
|
SOCS-1(h) + Jak2(h) <==> SOCS-1(h):Jak2(h) (binding)
|
ErbB1(h) + Jak2(h) <==> ErbB1(h):Jak2(h) (binding)
|
ErbB2(h) + Jak2(h) <==> ErbB2(h):Jak2(h) (binding)
|
Jak2(h) + ATP --> Jak2(h){p} + ADP (phosphorylation)
|
IL-5Ralpha(h) + Jak2(h) <==> IL-5Ralpha(h):Jak2(h) (binding)
|
Jak2(h) + ATP --> Jak2(h){p} + ADP (phosphorylation; automodification)
|
Jak2(h) + brca1(h) <==> Jak2(h):brca1(h) (binding)
|
Jak2(h) + IRS-1(h) <==> Jak2(h):IRS-1(h) (binding)
|
Jak2(h) + 2 ATP --> Jak2(h){pY1007}{pY1008} + 2 ADP (phosphorylation)
|
Jak2(h) --> IL8(h) (transactivation)
|
IL-5Rbeta(m.s.) + Jak2(h) <==> IL-5Rbeta(m.s.):Jak2(h) (binding)
|
IL-5Rbeta(h) + Jak2(h) <==> IL-5Rbeta(h):Jak2(h) (binding)
|
Jak2(h) + PLCgamma(h) <==> Jak2(h):PLCgamma(h) (binding)
|
Jak2(h) + STAT1(h) <==> Jak2(h):STAT1(h) (binding)
|
p85(m) + Jak2(h) <==> p85(m):Jak2(h) (binding)
|
Jak2(h) + dynamin2(h) <==> Jak2(h):dynamin2(h) (binding)
|
IL-17A(h) --> Jak2(h) (activation; phosphorylation)
|
JAK2(h) --> Jak2(h) (expression).
|
IFNgamma(m.s.) --> Jak2(h) (increase of abundance)
|
IFNgamma(h) --> Jak2(h) (increase of abundance)
|
ErbB1-p170(h){pY1016} + Jak2(h) <==> ErbB1-p170(h){pY1016}:Jak2(h) (binding)
|
ErbB2(h){pY1023}{pY1221}{pY1222} + Jak2(h) <==> ErbB2(h){pY1023}{pY1221}{pY1222}:Jak2(h) (binding)
|
ErbB3-isoform1(h){pY1276} + Jak2(h) <==> ErbB3-isoform1(h){pY1276}:Jak2(h) (binding)
|
Jak2(h) + prlr(r) <==> Jak2(h):prlr(r) (binding)
|
prlr(m.s.) + Jak2(h) <==> prlr(m.s.):Jak2(h) (binding)
|
Jak2(h) + ATP --> Jak2(h){pY} + ADP (phosphorylation)
|
JAK2(h) --> Jak2(h) (expression).
|
