| IRF-3(h) + IRF-5(h) <==> IRF-3(h):IRF-5(h) (binding).
|
IRF-3(h) --> CCL5(h) (DNA binding).
|
TRIF(h) + IRF-3(h) <==> TRIF(h):IRF-3(h) (binding)
|
TRAM(h) + IRF-3(h) <==> TRAM(h):IRF-3(h) (binding)
|
TBK1(h) + IRF-3(h) <==> TBK1(h):IRF-3(h) (binding)
|
IKK-i(h) + IRF-3(h) <==> IKK-i(h):IRF-3(h) (binding)
|
IRF-3(h) + ATP --IKK-i(h){p}--> IRF-3(h){p} + ADP (phosphorylation)
|
IRF-3(h) + ATP --TBK1(h)--> IRF-3(h){p} + ADP (phosphorylation)
|
TIRAP(v.s.) + IRF-3(h) <==> TIRAP(v.s.):IRF-3(h) (binding)
|
IRF-3(h) + ATP --IKK-beta(h)--> IRF-3(h){p} + ADP (phosphorylation)
|
2 IRF-3(h) <==> (IRF-3(h))2 (binding; oligomerization)
|
IRF-3(h) + p300(h) <==> IRF-3(h):p300(h) (binding)
|
IRF-3(h) + CBP(m) <==> IRF-3(h):CBP(m) (binding)
|
IRF-3(h) + CBP(h) <==> IRF-3(h):CBP(h) (binding)
|
IRF-3(h) --> IFNA1(h) (DNA binding; transregulation).
|
IRF-3(h) + ATP --> IRF-3(h){p} + ADP (phosphorylation)
|
TBK1(h) + IRF-3(h) <==> TBK1(h):IRF-3(h) (binding)
|
IRF-3(h) --> IRF-3(h) (translocation)
|
IRF-3(h) + ATP --> IRF-3(h){pS386} + ADP (phosphorylation)
|
IRF-3(h) + ATP --> IRF-3(h){pS396} + ADP (phosphorylation)
|
CBP(h) + IRF-3(h) <==> CBP(h):IRF-3(h) (binding)
|
IRF-3(h) + Prdx1(h) <==> IRF-3(h):Prdx1(h) (binding)
|
IRF-3(h) --> CCL19(h) (DNA binding).
|
IRF-3(h) + Ro52(h) <==> IRF-3(h):Ro52(h) (binding)
|
IRF-3(h) + n ubiquitin(h) --> IRF-3(h){ub}n (ubiquitination)
|
IRF-3(h) --> protein remnants (degradation)
|
IRF-3(h) + n ATP --> IRF-3(h){p}n + n ADP (phosphorylation)
|
Pin1(h) + IRF-3(h) <==> Pin1(h):IRF-3(h) (binding)
|
Pin1(m.s.) + IRF-3(h) <==> Pin1(m.s.):IRF-3(h) (binding)
|
IRF-3(h) + n ubiquitin(m.s.) --> IRF-3(h){ub}n (ubiquitination)
|
IRF-3(h) --> NOS2(h) (DNA binding).
|
IRF-3(h) --> ABCC2(h) (DNA binding; transactivation).
|
IRF-3(h) + ATP --> IRF-3(h){pS398} + ADP (phosphorylation)
|
IRF-3(h) --> ISG15(h) (DNA binding).
|
IRF-3(h) --> IFNB1(h) (DNA binding).
|
IRF-3(h) --> IFNA14(h) (DNA binding).
|
IRF-3(h) --> IL12A(h) (DNA binding).
|
IRF-3(h) --> IL28B(h) (DNA binding).
|
IRF-3(h) --> IL29(h) (DNA binding).
|
IRF3(h) --> IRF-3(h) (expression).
|
HCV-NS5A(HCV) --> IRF-3(h) (increase of abundance)
|
HCV-NS3-1A(HCV1A):HCV-NS4A-1A(HCV1A) --> IRF-3(h) (decrease of transport)
|
IRF-3(h) --> IRF-3(h) (translocation)
|
IRF-3(h) --> IFNA1(h) (DNA binding; transactivation).
|
IRF-3(h) --> IFNB1(h) (DNA binding; transactivation).
|
IRF-3(h) --/ IFNA4(m) (DNA binding; transrepression).
|
IRF-3(h) --> ISG15(h) (DNA binding; transactivation).
|
IRF-3(h) --> IRF7(h) (DNA binding).
|
IRF-3(h) --> Ifnb1(m) (transactivation)
|
IRF-3(h) + ATP --> IRF-3(h){pS339} + ADP (phosphorylation)
|
IRF-3(h) + 2 ATP --> IRF-3(h){pS339}{pS396} + 2 ADP (phosphorylation)
|
IRF-3(h) + 2 ATP --IKK-i(m.s.):TBK1(m.s.)--> IRF-3(h){pS339}{pS396} + 2 ADP (phosphorylation)
|
2 IRF-3(h) <==> (IRF-3(h))2 (binding; oligomerization)
|
IRF-3(h) + ATP --TBK1(m.s.)--> IRF-3(h){pS386} + ADP (phosphorylation)
|
IRF-3(h) + n ATP --TBK1(m.s.)--> IRF-3(h){p}n + ADP (phosphorylation)
|
IRF3(h) --> IRF-3(h) (expression).
|
