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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

InsR(h) + APS(m) <==> InsR(h):APS(m) (binding)
InsR(h) + MAD2(h) <==> InsR(h):MAD2(h) (binding)
insulin(pg) + InsR(h) <==> insulin(pg):InsR(h) (binding)
InsR(h) + ATP --> InsR(h){pY1158} + ADP (phosphorylation)
IRS-1(r) + InsR(h) <==> IRS-1(r):InsR(h) (binding)
InsR(h) + ATP --> InsR(h){pY} + ADP (phosphorylation; automodification)
InsR(h) --> SHP-1(h){p} (activation; increase of phosphorylation)
InsR(h) + SOCS-1(h) <==> InsR(h):SOCS-1(h) (binding)
SOCS-6(m) + InsR(h) <==> SOCS-6(m):InsR(h) (binding)
Fetua(h) --/ InsR(h) (inhibition)
INSR(h) --> InsR(h) (expression).
insulin(h) --> InsR(h) (binding).
InsR(h){pY} --PTP1B(h)--> InsR(h) + p (dephosphorylation)
insulin(h) + InsR-A(h) <==> insulin(h):InsR-A(h) (binding)
InsR-A(h) + ATP --> InsR-A(h){pY} + ADP (phosphorylation)
INSR(h) --> InsR-A(h) (expression).
insulin(h) --> InsR-A(h) (binding).
insulin(h) + InsR-B(h) <==> insulin(h):InsR-B(h) (binding)
InsR-B(h) + ATP --> InsR-B(h){pY} + ADP (phosphorylation)
InsR-B(h) + STAT5(h) <==> InsR-B(h):STAT5(h) (binding)
InsR-B(h) + STAT5B(m) <==> InsR-B(h):STAT5B(m) (binding)
INSR(h) --> InsR-B(h) (expression).
insulin(h) --> InsR-B(h) (binding).

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top