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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

IL-6(h) + IL-6R(h) <==> IL-6(h):IL-6R(h) (binding)
IL-6(h) --> TLR7(h) (transactivation)
IL-6(h) --> TLR8(h) (transactivation)
IL-6(h) --> STAT3(m){pY705} (increase of phosphorylation)
IL-6(h) --> STAT3(h){pY} (increase of phosphorylation)
IL-6(h) --> STAT3-isoform1(m):gp130(m.s.){pY} (increase of binding)
IL-6(h) --> STAT3-isoform1(m):PKCdelta(m):gp130(m.s.){pY} (increase of binding)
IL-17A(h) --> IL-6(h) (activation)
IL6(h) --> IL-6(h) (expression).
estradiol --/ IL-6(h) (decrease of secretion)
relaxin-2(h) --> IL-6(h) (decrease of secretion)
FcgammaRI alpha(h) --> IL-6(h) (decrease of secretion)
FcgammaRIIA(h) --> IL-6(h) (decrease of secretion)
FCgammaRIIIA(h) --> IL-6(h) (decrease of secretion)
beta-arrestin1(m.s.) --> IL-6(h) (decrease of secretion)
IL-1beta(m.s.) --> IL-6(h) (increase of abundance)
CD154(h) --> IL-6(h) (increase of abundance)
SLAM(h) --/ IL-6(h) (decrease of abundance)
IFNgamma(m.s.) --> IL-6(h) (increase of secretion)
G-CSF(m.s.) --> IL-6(h) (increase of secretion)
IFNgamma(h) --> IL-6(h) (increase of secretion)
IL-17F(h) --> IL-6(h) (increase of secretion)
IL-17A(h):IL-17F(h) --> IL-6(h) (increase of secretion)
IL-17A(h) --> IL-6(h) (increase of secretion)
IL-17A(m.s.) --> IL-6(h) (increase of secretion)
TNF-alpha(m.s.) --> IL-6(h) (increase of secretion)
TRAM(h) --> IL-6(h) (decrease of secretion)
TNF(m.s.) --> IL-6(h) (increase of secretion)
IL-1(m.s.) --> IL-6(h) (increase of abundance)
TNF(m.s.) --> IL-6(h) (increase of abundance)
IL-17A(m.s.) --> IL-6(h) (increase of abundance)
IL-17F(m.s.) --> IL-6(h) (increase of abundance)
H2O2 --> IL-6(h) (increase of secretion)
CpG A --> IL-6(h) (increase of secretion)
3pRNA --> IL-6(h) (increase of secretion)
IL-1beta(m.s.) --> IL-6(h) (increase of secretion)
TILRR(h) --> IL-6(h) (increase of secretion)
CpG C --> IL-6(h) (increase of secretion)
rnf11(h) --> IL-6(h) (decrease of secretion)
LPS(ECO) --> IL-6(h) (increase of secretion)
LPS --> IL-6(h) (increase of secretion)
IL-6(h) --> STAT3(m):Rac2(m):MgcRacGAP(m) (increase of binding)
IL-6(h) --> MgcRacGAP(h):STAT3(m) (increase of binding)
IL-6(h) --> MgcRacGAP(h):Rac1(m) (increase of binding)
IL-6(h) --> STAT3(h){pY705} (increase of phosphorylation)
IL-6(h) --> STAT3(h){pY} (increase of phosphorylation)
IL-6(h) --> CEBPD(h) (transactivation)
IL-6(h) --> Tbxas1(r) (transactivation)
IL-6(h) --> Cdk9(m.s.):gp130(m.s.) (increase of binding)
IL-6(h) --/ gp130(r) (decrease of abundance)
IL-6(h) --> STAT3(gl){pY705} (increase of phosphorylation)
IL-6(h) --> STAT5(gl){pY} (increase of phosphorylation)
IL-6(h) --> STAT3(r){pY705} (increase of phosphorylation)
IL-6(h) --> STAT3(h){p} (increase of phosphorylation)
IL-6(h) --> C/EBPdelta(h) (increase of abundance)
IL-6(h) --> CRP(h) (increase of secretion)
IL-6(h) --> DEFB4(h) (transactivation)
IL-6(h) --> STAT3(m){pY705} (increase of phosphorylation)
IL-6(h) --> STAT3(h){aceK685} (increase of acetylation)
IL-6(h) --> STAT3(h){pY705}{pS727} (increase of phosphorylation)
IL-6(h) + IL-6R(m.s.) <==> IL-6(h):IL-6R(m.s.) (binding)
IL-6(h) --> STAT3(m){pY} (increase of phosphorylation)
gp130-isoform1(h) + IL-6(h) <==> gp130-isoform1(h):IL-6(h) (binding)
IL-6(h) --> (gp130-isoform1(h))2 (increase of binding)
IL-6(h) --> STAT3(m):STAT3(m) (increase of binding)
IL-6(h) --> Vav(h){pY} (increase of phosphorylation)
IL-6(h) --> Vav(h):gp130-isoform1(h) (increase of binding)
IL-6(h) --> MBP(m.s.){p} (increase of phosphorylation)
IL-6(h) --/ collagen(rb) (decrease of abundance)
IL-6(h) --/ collagen-II(rb) (decrease of abundance)
IL-6(h) --/ COL2A1(rb) (transrepression)
IL-6(h) --/ COL2A1(h) (transrepression)
IL-6(h) --/ SP1(rb) (transrepression)
IL-6(h) --> SP3(rb) (transactivation)
IL-6(h) --/ Sp1(rb) (decrease of abundance)
IL-6(h) --/ Sp3(rb) (decrease of abundance)
IL-6(h) --> SHP-2(r){pY} (increase of phosphorylation)
IL-6(h) --> gp130(r){pY} (increase of phosphorylation)
IL-6(h) --> STAT3(r){pY} (increase of phosphorylation)
IL-6(h) --> ERK1(r){p} (increase of phosphorylation)
IL-6(h) --> ERK2(r){pY} (increase of phosphorylation)
IL-6(h) --> Grb-2(r):SHP-2(r){pY} (increase of binding)
IL-6(h) --> ERK1(h){p} (increase of phosphorylation)
IL-6(h) --> ERK2(h){p} (increase of phosphorylation)
IL-6(h) --> SHP-2(m){pY} (increase of phosphorylation)
IL-6(h) --> Egr1(r) (transactivation)
IL-6(h) --> Fos(r) (transactivation)
IL-6(h) --> Jun(r) (transactivation)
IL-6(h) --> JUNB(r) (transactivation)
IL-6(h) --> Hp(r) (transactivation)
IL-6(h) --> haptoglobin(r) (increase of secretion)
IL-6(h) --> JUNB(h) (transactivation)
IL-6(h) --> ZFP36(h) (transactivation)
IL-6(h) --> STAT3-isoform1(h){pY705}{pS727} (increase of phosphorylation)
IL-6(h) --> JunB(h) (increase of abundance).
IL-6(h) --> histone H3(h){aceK15} (increase of acetylation)
IL-6(h) --> histone H4(h){ace} (increase of acetylation)
IL-6(h) --> Jak1(m.s.){pY} (increase of phosphorylation)
IL6(h) --> IL-6(h) (expression).

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Human U133A/GNF1H Gene Atlas  | Top