| IL-2(h) + IL-2Rbeta(h) <==> IL-2(h):IL-2Rbeta(h) (binding)
|
IL-2(h) + gamma-c(m):IL-2Rbeta(h) <==> IL-2(h):gamma-c(m):IL-2Rbeta(h) (binding)
|
IL2(h) --> IL-2(h) (expression).
|
KRC(m.s.) --> IL-2(h) (increase of abundance)
|
CD45(m) --> IL-2(h) (increase of abundance)
|
CD3(h) --> IL-2(h) (increase of secretion)
|
rps3(h) --> IL-2(h) (increase of abundance)
|
MALT1-isoform1(h) --> IL-2(h) (increase of secretion)
|
A20(h) --> IL-2(h) (decrease of secretion)
|
PTP-PEST(m) --> IL-2(h) (decrease of secretion)
|
RasGRP(h) --> IL-2(h) (increase of secretion)
|
IL-2(h) --> Jak3(h){pY} (increase of phosphorylation)
|
IL-2(h) --> VIL(h){pY} (increase of phosphorylation)
|
IL-2(h) --> Jak3(h):VIL(h) (increase of binding)
|
IL-2(h) --> FOXO1A(m){pT24} (increase of phosphorylation)
|
IL-2(h) --> ERK1(m){pT203}{pY205} (increase of phosphorylation)
|
IL-2(h) --> ERK2(m){pT183}{pY185} (increase of phosphorylation)
|
IL2(h) --> IL-2(h) (expression).
|
