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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

IGF-1R(h) + GIPC1(m) <==> IGF-1R(h):GIPC1(m) (binding)
IGF-1R(h) + p85beta(m) <==> IGF-1R(h):p85beta(m) (binding)
IGF-1R(h) + GIPC1(h) <==> IGF-1R(h):GIPC1(h) (binding)
IGF-1R(h) + 14-3-3epsilon(v.s.) <==> IGF-1R(h):14-3-3epsilon(v.s.) (binding)
beta1-integrin(h) + IGF-1R(h) <==> beta1-integrin(h):IGF-1R(h) (binding)
IGF-1R(h) + p85(m.s.) <==> IGF-1R(h):p85(m.s.) (binding)
Shc-1(h) + IGF-1R(h) <==> Shc-1(h):IGF-1R(h) (binding)
IRS-1(h) + IGF-1R(h) <==> IRS-1(h):IGF-1R(h) (binding)
IGF-1R(h) + ATP --> IGF-1R(h){pY} + ADP (phosphorylation)
SOCS-2(h) + IGF-1R(h) <==> SOCS-2(h):IGF-1R(h) (binding)
IGF-1R(h) --PACE(h)--> IGF-1R-alpha-p130(h) + IGF-1R-beta-p97(h) (cleavage)
IGF-1R(h) + IGF-1(h) <==> IGF-1R(h):IGF-1(h) (binding)
IGF-1R(h) --trypsin-1(m.s.)--> IGF-1R-alpha-p130(h) + IGF-1R-beta-p97(h) + IGF-1R-beta-p102(h) (cleavage)
IGF-1R(h) + ATP --> IGF-1R(h){pY} + ADP (phosphorylation; automodification)
IGF-1R(h) --PACE(h)--> IGF-1R-beta-p97(h) + protein remnants (cleavage)
IGF-1R(h) --PC5a(m)--> IGF-1R-beta-p97(h) + protein remnants (cleavage)
IGF-2(m.s.) + IGF-1R(h) <==> IGF-2(m.s.):IGF-1R(h) (binding)
14-3-3gamma(h) + IGF-1R(h) <==> 14-3-3gamma(h):IGF-1R(h) (binding)
ErbB1(h) + IGF-1R(h) <==> ErbB1(h):IGF-1R(h) (binding)
Src(h) + IGF-1R(h) <==> Src(h):IGF-1R(h) (binding)
IGF-1R(h) + 2 ATP --> IGF-1R(h){pY1161}{pY1346} + 2 ADP (phosphorylation)
IGF-1R(h) + PDK1(h){pS241} <==> IGF-1R(h):PDK1(h){pS241} (binding)
PDK1(h) + IGF-1R(h) <==> PDK1(h):IGF-1R(h) (binding)
IGF1R(h) --> IGF-1R(h) (expression).
atad2(h) --> IGF-1R(h) (increase of abundance)
IGF-1R(h) + ATP --> IGF-1R(h){pY} + ADP (phosphorylation; automodification)
IGF-1R(h) + PDK1-isoform1(h) <==> IGF-1R(h):PDK1-isoform1(h) (binding)
IGF1R(h) --> IGF-1R(h) (expression).

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top