| HIF-1alpha(h) + Hsp90(h) <==> HIF-1alpha(h):Hsp90(h) (binding)
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HNF-4alpha2(h) + HIF-1alpha(h) <==> HNF-4alpha2(h):HIF-1alpha(h) (binding)
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Smad3(h) + HIF-1alpha(h) <==> Smad3(h):HIF-1alpha(h) (binding)
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HIF-1alpha(h) + p300(h) <==> HIF-1alpha(h):p300(h) (binding)
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HIF-1alpha(h) + p53(h) <==> HIF-1alpha(h):p53(h) (binding)
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HIF-1alpha(h) + CBP(v.s.) <==> HIF-1alpha(h):CBP(v.s.) (binding)
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HIF-1alpha(h) + FIH-1(h) <==> HIF-1alpha(h):FIH-1(h) (binding)
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HIF-1alpha(h) + VHL(h) <==> HIF-1alpha(h):VHL(h) (binding)
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HIF-1alpha(h) --egln2(h)--> HIF-1alpha(h){hydP567} (hydroxylation)
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HIF-1alpha(h) --HIF-PH2(h)--> HIF-1alpha(h){hydP567} (hydroxylation)
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HIF-1alpha(h) --HIF-PH3(h)--> HIF-1alpha(h){hydP567} (hydroxylation)
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HIF-1alpha(h) --egln2(h)--> HIF-1alpha(h){hydP564} (hydroxylation)
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HIF-1alpha(h) --HIF-PH2(h)--> HIF-1alpha(h){hydP564} (hydroxylation)
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HIF-1alpha(h) --HIF-PH3(h)--> HIF-1alpha(h){hydP564} (hydroxylation)
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HIF-1alpha(h) --egln2(h)--> HIF-1alpha(h){hydP} (hydroxylation)
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HIF-1alpha(h) + VHL(h):elongin B(h):elongin C(h) <==> HIF-1alpha(h):VHL(h):elongin B(h):elongin C(h) (binding)
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HIF-1alpha(h) + n ubiquitin(h) --VHL(h)--> HIF-1alpha(h){ub(n)} (ubiquitination)
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HIF-1alpha(h) + ATP --ERK2(r){p}--> HIF-1alpha(h){p} + ADP (phosphorylation)
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HIF-1alpha(h) + JAB1(m) <==> HIF-1alpha(h):JAB1(m) (binding)
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HIF-1alpha(h) + Hsp90(mo) <==> HIF-1alpha(h):Hsp90(mo) (binding)
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HIF-1alpha(h) + SRC-1(h) <==> HIF-1alpha(h):SRC-1(h) (binding)
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Ref-1(h) + HIF-1alpha(h) <==> Ref-1(h):HIF-1alpha(h) (binding)
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HIF-1alpha(h) + mdm2(h) <==> HIF-1alpha(h):mdm2(h) (binding)
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HIF-1alpha(h) + arnt(h) <==> HIF-1(h) (binding)
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HIF-1alpha(h) + Per1(m) <==> HIF-1alpha(h):Per1(m) (binding)
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p16INK4a-p14(h) + HIF-1alpha(h) <==> p16INK4a-p14(h):HIF-1alpha(h) (binding)
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XAPC7(h) + HIF-1alpha(h) <==> XAPC7(h):HIF-1alpha(h) (binding)
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BMAL1(h) + HIF-1alpha(h) <==> HIF-1alpha(h):BMAL1(h) (binding)
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HIF-1alpha(h) + DAP3(h) <==> HIF-1alpha(h):DAP3(h) (binding)
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brca1(h) + HIF-1alpha(h) <==> brca1(h):HIF-1alpha(h) (binding)
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HIF-1alpha(h) --> NPPB(h) (DNA binding; transactivation).
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HIF-1alpha(h) --> Epo(h) (DNA binding; transactivation).
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HIF-1alpha(h) --> TFRC(h) (DNA binding).
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HIF-1alpha(h) --> NTRK2(h) (DNA binding).
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HIF-1alpha(h) --> RORA(m) (DNA binding).
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HIF-1alpha(h) --> PFKFB3(h) (DNA binding).
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HIF-1alpha(h) + HNF-4alpha(h) <==> HIF-1alpha(h):HNF-4alpha(h) (binding)
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HIF-1alpha(h) + CT5.4(h) <==> HIF-1alpha(h):CT5.4(h) (binding)
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HIF-1alpha(h) --> CEBPA(h) (DNA binding).
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HIF-1alpha(h) --> CXCR4(h) (DNA binding).
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HIF-1alpha(h) --> VEGFA(h) (DNA binding; transactivation).
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HIF-1alpha(h) --> RPSA(h) (DNA binding).
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HIF-1alpha(h) --> BCL2L1(h) (DNA binding).
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HIF-1alpha(h) --> CP(h) (DNA binding).
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HIF-1alpha(h) --> MUC1(h) (DNA binding).
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HIF-1alpha(h) --> ENG(h) (DNA binding).
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HIF-1alpha(h) --> TWIST1(h) (DNA binding).
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HIF-1alpha(h) --> Egln1(m) (transactivation)
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HIF-1alpha(h) --> HIF-1alpha(h) (translocation)
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HIF-1alpha(h) --> SERPINE1(h) (DNA binding).
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HIF-1alpha(h) --> CCL5(h) (DNA binding).
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HIF-1alpha(h) --> EGLN1(h) (DNA binding).
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HIF-1alpha(h) --> MIF(h) (DNA binding).
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HIF-1alpha(h) --> TFF3(h) (transactivation)
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HIF-1alpha(h) --> Nppa(r) (transactivation)
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HIF-1alpha(h) --> CXCL12(h) (transactivation)
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HIF-1alpha(h) --> TF(h) (DNA binding).
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HIF-1alpha(h) --> EDN1(h) (DNA binding).
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HIF-1alpha(h) + VHL(m.s.) <==> HIF-1alpha(h):VHL(m.s.) (binding)
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HIF-1alpha(h) + n ubiquitin(h) --> HIF-1alpha(h){ub(n)} (ubiquitination)
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HIF-1alpha(h) --> Pklr(r) (DNA binding).
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HIF-1alpha(h) --> ALOX5AP(h) (DNA binding).
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HIF-1alpha(h) --> PLAUR(h) (DNA binding).
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HIF-1alpha(h) --> SLC16A3(h) (DNA binding).
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HIF-1alpha(h) --> MIRN210(h) (DNA binding).
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HIF1A(h) --> HIF-1alpha(h) (expression).
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ET-1(m.s.) --> HIF-1alpha(h) (increase of abundance)
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ET3(m.s.) --> HIF-1alpha(h) (increase of abundance)
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TNF(h) --> HIF-1alpha(h) (increase of abundance)
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IL-1alpha(m.s.) --> HIF-1alpha(h) (increase of abundance)
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IFNalpha2a(h) --> HIF-1alpha(h) (increase of abundance)
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HIF-1alpha(h) --> HIF-1alpha(h) (translocation)
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JAB1(h) --> HIF-1alpha(h) (increase of abundance)
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COPS2(h) --> HIF-1alpha(h) (increase of abundance)
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HIF-1alpha-isoform1(h) --> TERT(h) (DNA binding; transactivation).
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SSAT(h) + HIF-1alpha-isoform1(h) <==> SSAT(h):HIF-1alpha-isoform1(h) (binding)
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RACK1(m.s.) + HIF-1alpha-isoform1(h) <==> RACK1(m.s.):HIF-1alpha-isoform1(h) (binding)
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Hsp90(m.s.) + HIF-1alpha-isoform1(h) <==> Hsp90(m.s.):HIF-1alpha-isoform1(h) (binding)
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HIF-1alpha-isoform1(h) --> VEGFA(h) (DNA binding; transactivation).
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HIF1A(h) --> HIF-1alpha-isoform1(h) (expression).
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HIF-1alpha-isoform2(h) + arnt(m.s.) <==> HIF-1alpha-isoform2(h):arnt(m.s.) (binding)
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HIF-1alpha-isoform2(h) --> Epo(h) (DNA binding; transactivation).
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HIF1A(h) --> HIF-1alpha-isoform2(h) (expression).
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HIF1A(h) --> HIF1A(h) (expression).
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hsa-miR-17-5p --/ HIF1A(h) (translational repression).
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hsa-miR-20a --/ HIF1A(h) (translational repression).
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hsa-miR-18a --/ HIF1A(h) (translational repression).
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hsa-miR-155 --/ HIF1A(h) (increase of mRNA decay).
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hsa-miR-199 --/ HIF1A(h) (increase of mRNA decay).
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rno-miR-155 --/ HIF1A(h) (increase of mRNA decay).
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rno-miR-199 --/ HIF1A(h) (increase of mRNA decay).
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hsa-miR-135 --/ HIF1A(h) (increase of mRNA decay).
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rno-miR-135 --/ HIF1A(h) (increase of mRNA decay).
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