| GZMB(h) --> granzymeB(h) (expression).
|
proCaspase-3(h) --granzymeB(h)--> Caspase-3-p20(h) + Caspase-3-p12(h) (processing)
|
proCaspase-7(h) --granzymeB(h)--> Caspase-7-p12(h) + Caspase-7-p20(h) + protein remnants (processing)
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proCaspase-10(h) --granzymeB(h)--> Caspase-10-p12(h) + protein remnants (processing)
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Bid(m) --granzymeB(h)--> protein remnants (processing)
|
proCaspase-9(h) --granzymeB(h)--> Caspase-9-p35(h) + Caspase-9-p10(h) (processing)
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Bid(v.s.) --granzymeB(h)--> tBid-p13(v.s.) + protein remnants (processing)
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ABP-280(h) --granzymeB(h)--> ABP-280-p205(h) + protein remnants (cleavage)
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ABP-280(h) --granzymeB(h)--> ABP-280-p200(h) + protein remnants (cleavage)
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ABP-280(h) --granzymeB(h)--> ABP-280-p110(h) + protein remnants (cleavage)
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ABP-280(h) + granzymeB(h) <==> ABP-280(h):granzymeB(h) (binding)
|
GZMB(h) --> granzymeB(h) (expression).
|
Bid(h) --granzymeB(h)--> protein remnants (cleavage)
|
proCaspase-3(h) --granzymeB(h)--> Caspase-3-p19(h) + Caspase-3-p17(h) (cleavage)
|
