| ErbB1(h) + Cdc25A(h) <==> ErbB1(h):Cdc25A(h) (binding)
|
HB-EGF(h) + ErbB1(h) <==> HB-EGF(h):ErbB1(h) (binding)
|
EGF(h) + ErbB1(h) <==> EGF(h):ErbB1(h) (binding)
|
ErbB1(h) + PI3K-C2alpha(h) <==> ErbB1(h):PI3K-C2alpha(h) (binding)
|
ErbB1(h) + PI3K-C2beta(h) <==> ErbB1(h):PI3K-C2beta(h) (binding)
|
ErbB1(h) + STAT1(h) <==> ErbB1(h):STAT1(h) (binding)
|
ErbB1(h) + STAT3(h) <==> ErbB1(h):STAT3(h) (binding)
|
ErbB1(h) + Src(h) <==> ErbB1(h):Src(h) (binding)
|
ErbB1(h) + Jak2(h) <==> ErbB1(h):Jak2(h) (binding)
|
ErbB1(h) + ubiquitin(h) --c-Cbl(h),UbcH7(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + ubiquitin(h) --c-Cbl(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + c-Cbl(h) <==> ErbB1(h):c-Cbl(h) (binding)
|
ErbB1(h) + 2 ubiquitin(v.s.) --Cbl-b(h)--> ErbB1(h){ub(1)}{ub(1)} (ubiquitination)
|
ErbB1(h) + 2 ubiquitin(v.s.) --c-Cbl(h)--> ErbB1(h){ub(1)}{ub(1)} (ubiquitination)
|
ErbB1(h) + Pyk2-isoform1(h) <==> ErbB1(h):Pyk2-isoform1(h) (binding)
|
ErbB1(h) + ARF4(h) <==> ErbB1(h):ARF4(h) (binding)
|
ErbB1(h) + CIN85(h) <==> ErbB1(h):CIN85(h) (binding)
|
ErbB1(h) + endophilin 1(h) <==> ErbB1(h):endophilin 1(h) (binding)
|
ErbB1(h) + ATP --> ErbB1(h){pY1092} + ADP (phosphorylation; automodification)
|
ErbB1(h) + 2 ATP --> ErbB1(h){pY869}{pY1172} + 2 ADP (phosphorylation)
|
ErbB1(h) + Decorin(h) <==> Decorin(h):ErbB1(h) (binding)
|
NHERF-1(h) + ErbB1(h) <==> NHERF-1(h):ErbB1(h) (binding)
|
2 ErbB1(h) <==> (ErbB1(h))2 (oligomerization)
|
ErbB1(h) + ATP --> ErbB1(h){pY} + ADP (phosphorylation)
|
ErbB2(m.s.) + ErbB1(h) <==> ErbB2(m.s.):ErbB1(h) (binding)
|
3 ErbB1(h) <==> (ErbB1(h))3 (binding)
|
ErbB1(h) + caveolin-1(h) <==> ErbB1(h):caveolin-1(h) (binding)
|
caveolin-1(ca) + ErbB1(h) <==> caveolin-1(ca):ErbB1(h) (binding)
|
STAM2(m) + ErbB1(h) <==> STAM2(m):ErbB1(h) (binding)
|
Eps8(m) + ErbB1(h) <==> Eps8(m):ErbB1(h) (binding)
|
ErbB1(h) + Eps8(m) <==> ErbB1(h):Eps8(m) (binding)
|
ErbB2(h) + ErbB1(h) <==> ErbB1(h):ErbB2(h) (binding)
|
ErbB1(h) + ErbB2(h){pY1222} <==> ErbB1(h):ErbB2(h){pY1222} (binding)
|
ErbB2(h){pY1248} + ErbB1(h) <==> ErbB2(h){pY1248}:ErbB1(h) (binding)
|
LRIG1-xbb1(h) + ErbB1(h) <==> LRIG1-xbb1(h):ErbB1(h) (binding)
|
ErbB1(h) + ubiquitin(h) --> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + 6 ATP --> ErbB1(h){pT678}{pT693}{pS991}{pS1026}{pY1172}{pY1197} + 6 ADP (phosphorylation)
|
ErbB1(h) + ATP --> ErbB1(h){pY1016} + ADP (phosphorylation; automodification)
|
ErbB1(h) + ATP --Cdk1(x)--> ErbB1(h){pS1026} + ADP (phosphorylation)
|
ErbB1(h) + PTPRK(h) <==> PTPRK(h):ErbB1(h) (binding)
|
ErbB1(h) + 2 ATP --CaMKII(r)--> ErbB1(h){pS1070}{pS1071} + 2 ADP (phosphorylation)
|
ErbB1(h) + 3 ATP --> ErbB1(h){pS991}{pY998}{pY1172} + 3 ADP (phosphorylation)
|
ErbB1(h) + 12 NDP-Gly --> ErbB1(h){glyN56}{glyN128}{glyN175}{glyN196}{glyN352}{glyN361}{glyN413}{glyN444}{glyN528}{glyN568}{glyN603}{glyN623} + 12 NMP (glycosylation)
|
ErbB1(h) + 13 ATP --> ErbB1(h){pT693}{pS991}{pY1016}{pS1026}{pY1069}{pS1070}{pS1081}{pY1092}{pY1110}{pY1138}{pS1166}{pY1172}{pY1197} + 13 ADP (phosphorylation)
|
MRP-14(h) + ErbB1(h) <==> MRP-14(h):ErbB1(h) (binding)
|
CD98(h) + ErbB1(h) <==> CD98(h):ErbB1(h) (binding)
|
ErbB1(h) + clathrin LCa(h) <==> ErbB1(h):clathrin LCa(h) (binding)
|
ErbB1(h) + GAPD(h) <==> ErbB1(h):GAPD(h) (binding)
|
Grb-2(h) + ErbB1(h) <==> Grb-2(h):ErbB1(h) (binding)
|
ErbB1(h) + Lyn(h) <==> ErbB1(h):Lyn(h) (binding)
|
ErbB1(h) + 14-3-3sigma(h) <==> ErbB1(h):14-3-3sigma(h) (binding)
|
SHP1-isoform2(h) + ErbB1(h) <==> SHP1-isoform2(h):ErbB1(h) (binding)
|
ErbB1(h) + ATP --betaARK-1(b)--> ErbB1(h){pS} + ADP (phosphorylation)
|
ErbB1(h) + 3 ATP --> ErbB1(h){pY1092}{pY1110}{pY1197} + 3 ADP (phosphorylation; automodification)
|
p85alpha(h) + ErbB1(h) <==> p85alpha(h):ErbB1(h) (binding)
|
YMER-isoform1(h) + ErbB1(h) <==> YMER-isoform1(h):ErbB1(h) (binding)
|
ErbB1(h) + ubiquitin(h) --c-Cbl(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + ubiquitin(h) --Cbl-b(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + ubiquitin(h) --CBL-3L(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + ubiquitin(h) --c-Cbl(h),Ubc5B(h),E1(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + ubiquitin(h) --E1(h),Ubc5C(h),c-Cbl(h)--> ErbB1(h){ub} (ubiquitination)
|
ErbB1(h) + 3 ATP --> ErbB1(h){pS}{pT}{pY} + 3 ADP (phosphorylation)
|
ErbB1(h) + 5 ATP --> ErbB1(h){pY869}{pY1016}{pY1069}{pY1092}{pY1197} + 5 ADP (phosphorylation)
|
ErbB1(h) + DNA-PKcs(h) <==> ErbB1(h):DNA-PKcs(h) (binding)
|
ErbB1(h) + Ku70(h):Ku80(h) <==> ErbB1(h):Ku70(h):Ku80(h) (binding)
|
ErbB1(h) + DNA-PKcs(m) <==> ErbB1(h):DNA-PKcs(m) (binding)
|
ErbB1(h) + Ku80(m):Ku70(m) <==> ErbB1(h):Ku80(m):Ku70(m) (binding)
|
ErbB1(h) + ATP --> ErbB1(h){pY} + ADP (phosphorylation; automodification)
|
p85alpha(m.s.) + ErbB1(h) <==> p85alpha(m.s.):ErbB1(h) (binding)
|
p85beta(m.s.) + ErbB1(h) <==> p85beta(m.s.):ErbB1(h) (binding)
|
Syk(h) + ErbB1(h) <==> Syk(h):ErbB1(h) (binding)
|
ErbB1(h) + CAML(h) <==> ErbB1(h):CAML(h) (binding)
|
ErbB1(h) + 3 ATP --> ErbB1(h){pY869}{pY1092}{pY1197} + 3 ADP (phosphorylation; automodification)
|
ErbB1(h) + STAT5A(h) <==> ErbB1(h):STAT5A(h) (binding)
|
ErbB1(h) + STAT5B(h) <==> ErbB1(h):STAT5B(h) (binding)
|
ErbB1(h) + 4 ATP --> ErbB1(h){pY1092}{pY1110}{pY1172}{pY1197} + 4 ADP (phosphorylation)
|
ErbB1(h) + ATP --> ErbB1(h){pY1197} + ADP (phosphorylation)
|
ErbB1(h){pY1197} + ErbB1(h) <==> ErbB1(h){pY1197}:ErbB1(h) (binding)
|
ErbB1(h) + ErbB2(h) <==> ErbB1(h):ErbB2(h) (binding)
|
ErbB1(h) + ErbB2(h){pY1248} <==> ErbB1(h):ErbB2(h){pY1248} (binding)
|
ErbB1(h) + CD44(h) <==> ErbB1(h):CD44(h) (binding)
|
Src(m) + ErbB1(h) <==> Src(m):ErbB1(h) (binding)
|
ErbB1(h) + 2 ATP --> ErbB1(h){pY869}{pY1092} + 2 ADP (phosphorylation)
|
ErbB1(h) + PLSCR1(h) <==> ErbB1(h):PLSCR1(h) (binding)
|
ErbB1(h) --> protein remnants (degradation)
|
ErbB1(h) + Shc(m) + Grb-2(m) <==> ErbB1(h):Shc(m):Grb-2(m) (binding)
|
ErbB1(h) + ErbB2(h) + CD44(h) <==> ErbB1(h):ErbB2(h):CD44(h) (binding)
|
Eps8(h) + ErbB1(h) <==> Eps8(h):ErbB1(h) (binding)
|
ErbB1(h) + Shc-1-p66(h) <==> ErbB1(h):Shc-1-p66(h) (binding)
|
ErbB1(h) + Shc-1-p52(h) <==> ErbB1(h):Shc-1-p52(h) (binding)
|
ErbB1(h) + Shc-1-p46(h) <==> ErbB1(h):Shc-1-p46(h) (binding)
|
ErbB1(h) + Pyk2(h) <==> ErbB1(h):Pyk2(h) (binding)
|
ErbB1(h) + ErbB3(h) <==> ErbB1(h):ErbB3(h) (binding)
|
ErbB1(h) + ErbB4(h) <==> ErbB1(h):ErbB4(h) (binding)
|
ErbB1(h) + CBL-3L(h) <==> ErbB1(h):CBL-3L(h) (binding)
|
ErbB1(h) + STAT1alpha(h) <==> ErbB1(h):STAT1alpha(h) (binding)
|
ErbB1(h) + STAT1beta(h) <==> ErbB1(h):STAT1beta(h) (binding)
|
ErbB1(h) + PDGFRbeta(h) <==> ErbB1(h):PDGFRbeta(h) (binding)
|
ErbB1(h) + PDGFRbeta(h) <==> ErbB1(h):PDGFRbeta(h) (binding)
|
ErbB1(h) + proEPR(h) <==> ErbB1(h):proEPR(h) (binding)
|
ErbB1(h) --> ErbB1(h) (translocation)
|
ErbB1(h) + eps15(m.s.) <==> ErbB1(h):eps15(m.s.) (binding)
|
ErbB1(h) + epsin 1(m.s.) <==> ErbB1(h):epsin 1(m.s.) (binding)
|
ErbB1(h) + n ubiquitin(h) --> ErbB1(h){ub}n (ubiquitination)
|
ErbB1(h) + c-Cbl(m) <==> ErbB1(h):c-Cbl(m) (binding)
|
ErbB1(h) + Cbl-b(m) <==> ErbB1(h):Cbl-b(m) (binding)
|
ErbB1(h) + Grb-2(m.s.) <==> ErbB1(h):Grb-2(m.s.) (binding)
|
ErbB1(h) + Shc-1-p66(m) <==> ErbB1(h):Shc-1-p66(m) (binding)
|
ErbB1(h) + Shc-1-p46(m) <==> ErbB1(h):Shc-1-p46(m) (binding)
|
ErbB1(h) + BTC(h) <==> ErbB1(h):BTC(h) (binding)
|
ErbB1(h) + ATP --> ErbB1(h){p} + ADP (phosphorylation)
|
ErbB1(h) + HPRG(m.s.) <==> ErbB1(h):HPRG(m.s.) (binding)
|
Src(h){pY419} + ErbB1(h) <==> Src(h){pY419}:ErbB1(h) (binding)
|
ErbB1(h) + ER-alpha(h) <==> ErbB1(h):ER-alpha(h) (binding)
|
ErbB1(h) --> stromelysin1(h) (increase of abundance)
|
ErbB1(h) + 4 ATP --> ErbB1(h){pY869}{pY1016}{pY1069}{pY1092} + 4 ADP (phosphorylation)
|
ErbB1(h) + IGF-1R(h) <==> ErbB1(h):IGF-1R(h) (binding)
|
ErbB1(h) + p85(h) <==> ErbB1(h):p85(h) (binding)
|
ErbB1(h) + ATP --> ErbB1(h){pY869} + ADP (phosphorylation)
|
ErbB1(h) --/ Notch1(h) (decrease of abundance)
|
ErbB1(h) --/ HES1(h) (transrepression)
|
ErbB1(h) --/ NOTCH1(h) (transrepression)
|
ErbB1(h) --/ TP53(h) (transrepression)
|
ErbB1(h) --/ KRT1(h) (transrepression)
|
ErbB1(h) --/ KRT10(h) (transrepression)
|
ErbB1(h) --/ IVL(h) (transrepression)
|
ErbB1(h) --/ Keratin-1(h) (decrease of abundance)
|
ErbB1(h) --/ involucrin(h) (decrease of abundance)
|
ErbB1(h){pY} --Cdc25A(m.s.)--> ErbB1(h) + p (dephosphorylation)
|
c-Jun(h) --> ErbB1(h) (increase of abundance)
|
ErbB1(h){pY1092}{pY1197}{pY1016} --PTPRK(h)--> ErbB1(h) + p (dephosphorylation)
|
ErbB1(h){pY} --SHP1-isoform2(h)--> ErbB1(h) + p (dephosphorylation)
|
ErbB1(h){pY} --SHP-1(h)--> ErbB1(h) + p (dephosphorylation)
|
ErbB1(h) --> ErbB1(h) (translocation)
|
EGFR(h) --> ErbB1(h) (expression).
|
YB-1(m.s.) --> ErbB1(h) (increase of abundance)
|
YB-1(h) --> ErbB1(h) (increase of abundance)
|
eps15(m) + ATP --ErbB1(h)--> eps15(m){pY} + ADP (phosphorylation)
|
STAM2(m.s.) + ATP --ErbB1(h)--> STAM2(m.s.){pY} + ADP (phosphorylation)
|
eps15(m) + ATP --ErbB1(h)--> eps15(m){pY} + ADP (phosphorylation)
|
Eps8(m) + ATP --ErbB1(h)--> Eps8(m){pY} + ADP (phosphorylation)
|
EGFR(h) --> ErbB1-p60(h) (expression).
|
EGFR(h) --> ErbB1-p110(h) (expression).
|
ErbB1-p170(h) + NHERF-1(m) <==> NHERF-1(m):ErbB1-p170(h) (binding)
|
ErbB1-p170(h) + NHERF-1(m.s.) <==> NHERF-1(m.s.):ErbB1-p170(h) (binding)
|
2 ErbB1-p170(h) <==> (ErbB1-p170(h))2 (oligomerization)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY} + ADP (phosphorylation; automodification)
|
ErbB2(h) + ErbB1-p170(h) <==> ErbB2(h):ErbB1-p170(h) (binding)
|
ErbB1-p170(h) + caveolin-1(ca) <==> ErbB1-p170(h):caveolin-1(ca) (binding)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){p} + ADP (phosphorylation; automodification)
|
ErbB1-p170(h) + 2 ATP --> ErbB1-p170(h){pY869}{pY1125} + 2 ADP (phosphorylation)
|
ErbB1-p170(h) + 6 ubiquitin(h) --> ErbB1-p170(h){ubK716}{ubK737}{ubK754}{ubK867}{ubK929}{ubK970} (ubiquitination)
|
ErbB1-p170(h) + n ubiquitin(h) --> ErbB1-p170(h){ub(n)} (ubiquitination)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY1110} + ADP (phosphorylation)
|
ErbB1-p170(h) + ATP --Src(h)--> ErbB1-p170(h){pY869} + ADP (phosphorylation)
|
ErbB1-p170(h) + p56Dok-2(h) <==> p56Dok-2(h):ErbB1-p170(h) (binding)
|
ErbB1-p170(h) + fer(h) <==> ErbB1-p170(h):fer(h) (binding)
|
ErbB1-p170(h) + PTK6(h) <==> ErbB1-p170(h):PTK6(h) (binding)
|
ErbB1-p170(h) + RGS12(h) <==> ErbB1-p170(h):RGS12(h) (binding)
|
ErbB1-p170(h) + SH2D1A(h) <==> ErbB1-p170(h):SH2D1A(h) (binding)
|
ErbB1-p170(h) + 7 ATP --Src(h)--> ErbB1-p170(h){pY915}{pY944}{pY1016}{pY1092}{pY1110}{pY1172}{pY1197} + 7 ADP (phosphorylation)
|
ErbB1-p170(h) + 3 ATP --Abl(m)--> ErbB1-p170(h){pY1016}{pY1092}{pY1197} + 3 ADP (phosphorylation)
|
ErbB1-p170(h) + c-Cbl(m.s.) <==> c-Cbl(m.s.):ErbB1-p170(h) (binding)
|
ErbB1-p170(h) + ubiquitin(h) --> ErbB1-p170(h){ub} (ubiquitination)
|
ErbB1-p170(h) + 5 ATP --> ErbB1-p170(h){pY1016}{pY1092}{pY1110}{pY1172}{pY1197} + 5 ADP (phosphorylation; automodification)
|
ErbB1-p170(h) + 4 ATP --> ErbB1-p170(h){pT678}{pT693}{pS1070}{pS1071} + 4 ADP (phosphorylation)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY1197} + ADP (phosphorylation)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY1092} + ADP (phosphorylation)
|
ErbB1-p170(h) --> protein remnants (degradation)
|
ErbB1-p170(h) + PLCgamma1(m) <==> ErbB1-p170(h):PLCgamma1(m) (binding)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY1069} + ADP (phosphorylation)
|
ErbB1-p170(h) + ATP --> ErbB1-p170(h){pY1069} + ADP (automodification; phosphorylation)
|
EGFR(h) --> ErbB1-p170(h) (expression).
|
crkII(h) + ATP --ErbB1-p170(h)--> crkII(h){pY221} + ADP (phosphorylation)
|
ErbB4-JM-A(h) + 10 ATP --ErbB1-p170(h)--> ErbB4-JM-A(h){pY1022}{pY1056}{pY1150}{pY1162}{pY1188}{pY1202}{pY1221}{pY1242}{pY1258}{pY1284} + 10 ADP (phosphorylation)
|
ErbB3-isoform1(h) + 11 ATP --ErbB1-p170(h)--> ErbB3-isoform1(h){pY1054}{pY1159}{pY1197}{pY1199}{pY1222}{pY1224}{pY1260}{pY1262}{pY1276}{pY1289}{pY1328} + 11 ADP (phosphorylation)
|
ErbB2(h) + 7 ATP --ErbB1-p170(h)--> ErbB2(h){pY1023}{pY1127}{pY1139}{pY1196}{pY1221}{pY1222}{pY1248} + 7 ADP (phosphorylation)
|
ErbB3(r) + ATP --ErbB1-p170(h)--> ErbB3(r){pY} + ADP (phosphorylation)
|
EGFR(h) --> ErbB1-4(h) (expression).
|
EGFR(h) --> EGFR(h) (expression).
|
hsa-miR-7 --/ EGFR(h) (translational repression).
|
