| cyclinE(h):Cdk2(h) + p27Kip1(h) <==> cyclinE(h):Cdk2(h):p27Kip1(h) (binding)
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cyclinA(h):Cdk2(h) + p27Kip1(h) <==> cyclinA(h):Cdk2(h):p27Kip1(h) (binding)
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Cdk4(h) + p27Kip1(h) <==> Cdk4(h):p27Kip1(h) (binding)
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Cdk6(h) + p27Kip1(h) <==> Cdk6(h):p27Kip1(h) (binding)
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cyclinE(h) + p27Kip1(h) <==> cyclinE(h):p27Kip1(h) (binding)
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E2F-4(h):DP-1(h):p107(h):cyclinA(h):Cdk2(h) + p27Kip1(h) <==> E2F-4(h):DP-1(h):p107(h) + cyclinA(h):Cdk2(h):p27Kip1(h) (binding; dissociation)
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AKT-1(h){pT308} + p27Kip1(h) <==> AKT-1(h){pT308}:p27Kip1(h) (binding)
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AKT(h){pS473} + p27Kip1(h) <==> AKT(h){pS473}:p27Kip1(h) (binding)
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p27Kip1(h) + 2 ATP --AKT-1(h){pT308}{pS473}--> p27Kip1(h){pT157}{pT198} + 2 ADP (phosphorylation)
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JAB1(h) + p27Kip1(h) <==> JAB1(h):p27Kip1(h) (binding)
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p27Kip1(h) + Skp2(h) <==> p27Kip1(h):Skp2(h) (binding)
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cyclinE1(h) + p27Kip1(h) <==> cyclinE1(h):p27Kip1(h) (binding)
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Cdk2(h) + p27Kip1(h) <==> Cdk2(h):p27Kip1(h) (binding)
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p27Kip1(h) + cyclinD1(h) + Cdk4(h) <==> p27Kip1(h):cyclinD1(h):Cdk4(h) (binding)
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cyclinD1(h) + p27Kip1(h) <==> cyclinD1(h):p27Kip1(h) (binding)
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Cdk2(h) + p27Kip1(h) <==> Cdk2(h):p27Kip1(h) (binding)
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p27Kip1(h) --> protein remnants (degradation)
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p27Kip1(h) + CUL4A(m.s.) <==> p27Kip1(h):CUL4A(m.s.) (binding)
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p27Kip1(h) --> p27Kip1(h) (translocation)
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p27Kip1(h) + cyclinD2(h) <==> p27Kip1(h):cyclinD2(h) (binding)
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cyclinD3(h) + p27Kip1(h) <==> cyclinD3(h):p27Kip1(h) (binding)
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p27Kip1(h) + TRAF2(h) <==> p27Kip1(h):TRAF2(h) (binding)
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p27Kip1(h) + Pim(h) <==> p27Kip1(h):Pim(h) (binding)
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p27Kip1(h) + pim1(h) <==> p27Kip1(h):pim1(h) (binding)
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p27Kip1(h) + ATP --pim1(h)--> p27Kip1(h){p} + ADP (phosphorylation)
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p27Kip1(h) + cyclinA(h) <==> p27Kip1(h):cyclinA(h) (binding)
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p27Kip1(h) + ubiquitin(h) --> p27Kip1(h){ub} (ubiquitination)
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Hsc70(h) + p27Kip1(h) <==> Hsc70(h):p27Kip1(h) (binding)
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Histatin-3(h) + Hsc70-isoform1(h) + p27Kip1(h) <==> Histatin-3(h):Hsc70-isoform1(h):p27Kip1(h) (binding)
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CDKN1B(h) --> p27Kip1(h) (expression).
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E47(h) --> p27Kip1(h) (increase of abundance)
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SIRT1(m) --> p27Kip1(h) (increase of abundance)
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15d-PGJ2 --/ p27Kip1(h) (decrease of abundance)
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DDB1(h) --/ p27Kip1(h) (decrease of abundance)
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COPS1(h) --/ p27Kip1(h) (decrease of abundance)
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DDB1(h) --> p27Kip1(h) (decrease of transport)
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DDB1(m.s.) --/ p27Kip1(h) (decrease of abundance)
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Skp2(h) --/ p27Kip1(h) (decrease of abundance)
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ERK(h) --/ p27Kip1(h) (decrease of abundance)
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FOXO3a(m.s.) --> p27Kip1(h) (increase of abundance)
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p27Kip1(h) --> p27Kip1(h) (translocation)
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TGFbeta1(h) --> p27Kip1(h) (increase of abundance)
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Cdx-2(h) --/ p27Kip1(h) (decrease of abundance)
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s100a11(h) --/ p27Kip1(h) (decrease of abundance)
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Skp2(m.s.) --/ p27Kip1(h) (decrease of abundance)
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EGF(m.s.) --/ p27Kip1(h) (decrease of abundance)
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AKT-1(h) --/ p27Kip1(h) (decrease of abundance)
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Fzr(h) --> p27Kip1(h) (increase of abundance)
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p27Kip1(h) + Cdk4(h) <==> p27Kip1(h):Cdk4(h) (binding)
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p27Kip1(h) + cyclinE(h) + Cdk2(h) <==> p27Kip1(h):cyclinE(h):Cdk2(h) (binding)
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p27Kip1(h) + cyclinD1(h) <==> p27Kip1(h):cyclinD1(h) (binding)
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p27Kip1(h) + 2 ATP --pim1(h)--> p27Kip1(h){pT157}{pT198} + 2 ADP (phosphorylation)
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p27Kip1(h) + 14-3-3(h) <==> p27Kip1(h):14-3-3(h) (binding)
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p27Kip1(h) + 14-3-3beta(h) <==> p27Kip1(h):14-3-3beta(h) (binding)
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p27Kip1(h) + 14-3-3eta(h) <==> p27Kip1(h):14-3-3eta(h) (binding)
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p27Kip1(h) + 14-3-3sigma(h) <==> p27Kip1(h):14-3-3sigma(h) (binding)
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p27Kip1(h) + 14-3-3zeta(h) <==> p27Kip1(h):14-3-3zeta(h) (binding)
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p27Kip1(h) + 14-3-3gamma(h) <==> p27Kip1(h):14-3-3gamma(h) (binding)
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p27Kip1(h) + 14-3-3tau(h) <==> p27Kip1(h):14-3-3tau(h) (binding)
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p27Kip1(h) + n ubiquitin(h) --ATP,KPC1-isoform1(h),Ubc5A(h),E1(h)--> p27Kip1(h){ub(n)} (ubiquitination)
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CDKN1B(h) --> p27Kip1(h) (expression).
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p27Kip1(h){p} --Cdc14A(h)--> p27Kip1(h) + p (dephosphorylation)
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pim1(h) --/ p27Kip1(h) (decrease of abundance)
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CDKN1B(h) --> CDKN1B(h) (expression).
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hsa-miR-221 --/ CDKN1B(h) (increase of mRNA decay).
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hsa-miR-222 --/ CDKN1B(h) (increase of mRNA decay).
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