| Gene information | Literature | Expression | lncRNA | Mutation | Homolog |
Basic Information | |
|---|---|
Gene ID | 7803 |
Name | PTP4A1 |
Synonymous | protein tyrosine phosphatase type IVA, member 1;PTP4A1;protein tyrosine phosphatase type IVA, member 1 |
Definition | protein tyrosine phosphatase type IVA 1|protein tyrosine phosphatase type IVA protein 1|protein-tyrosine phosphatase 4a1|protein-tyrosine phosphatase of regenerating liver 1 |
Position | 6q12 |
Gene type | protein-coding |
Title | Abstract |
| Molecular mechanisms of the PRL phosphatases. | The phosphatases of regenerating liver (PRLs) are an intriguing family of dual specificity phosphatases due to their oncogenicity. The three members are small, single domain enzymes. We provide an overview of the phosphatases of regenerating liver, compare them to related phosphatases, and review recent reports about each phosphatase. Finally, we discuss similarities and differences between the phosphatases of regenerating liver, focusing on their molecular mechanisms and signalling pathways. |