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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2002

Name

ELK1

Synonymous

ELK1, member of ETS oncogene family;ELK1;ELK1, member of ETS oncogene family

Definition

ETS domain-containing protein Elk-1|ETS-like gene 1|tyrosine kinase (ELK1) oncogene

Position

Xp11.2

Gene type

protein-coding

Title

Abstract

Mouse Elk oncogene maps to chromosome X and a novel Elk oncogene (Elk3) maps to chromosome 10.

The Elk protein is a member of the Ets family found in both vertebrates and invertebrates. Human ELK1 encoded by ELK1 binds alone or together with serum response factor to DNA and regulates gene expression in a variety of biological processes. Using a panel of interspecific backcross mice, we have mapped the Elk oncogene (Elk) and a novel type Elk oncogene (Elk3), closely related to ELK1. Elk maps to Chr X, and Elk3 maps to the proximal region of Chr 10.