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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

993

Name

CDC25A

Synonymous

cell division cycle 25A;CDC25A;cell division cycle 25A

Definition

CDC25 isoform A1-CAG|CDC25A2-CAG isoform|M-phase inducer phosphatase 1|dual specificity phosphatase CDC25A

Position

3p21

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.393C>T; p.I131I; 3:48182965-48182965

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.960T>C; p.S320S; 3:48167915-48167915

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.363G>C; p.R121S; 3:48182995-48182995

 breastcarcinomaSubstitution - Missense

c.1324T>C; p.C442R; 3:48159454-48159454

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.232G>A; p.E78K; 3:48186718-48186718

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1305T>C; p.S435S; 3:48164324-48164324

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.854C>A; p.P285H; 3:48174360-48174360

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.286G>T; p.E96*; 3:48184657-48184657

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1474G>A; p.E492K; 3:48159046-48159046

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1262A>G; p.D421G; 3:48164367-48164367

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.606A>C; p.T202T; 3:48177932-48177932

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1336A>T; p.R446*; 3:48159442-48159442

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1336A>T; p.R446*; 3:48159442-48159442

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1336A>T; p.R446*; 3:48159442-48159442

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1450C>T; p.P484S; 3:48159070-48159070

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.1327C>T; p.R443W; 3:48159451-48159451

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.652T>A; p.F218I; 3:48177886-48177886

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.652T>A; p.F218I; 3:48177886-48177886

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.850C>A; p.P284T; 3:48174364-48174364

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1345_1346delGA; p.D449fs*4; 3:48159432-48159433

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.809G>A; p.R270Q; 3:48174405-48174405

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.809G>A; p.R270Q; 3:48174405-48174405

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.449A>G; p.K150R; 3:48180821-48180821

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1191+1G>A; p.?; 3:48165635-48165635

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.206G>C; p.S69T; 3:48186744-48186744

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.959C>A; p.S320Y; 3:48167916-48167916

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1271G>A; p.R424H; 3:48164358-48164358

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.259G>T; p.D87Y; 3:48184684-48184684

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.951C>T; p.S317S; 3:48167924-48167924

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1517G>A; p.R506Q; 3:48159003-48159003

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.652T>C; p.F218L; 3:48177886-48177886

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.94G>T; p.G32C; 3:48187854-48187854

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1301C>T; p.S434F; 3:48164328-48164328

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.110G>T; p.G37V; 3:48187838-48187838

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1046C>T; p.T349I; 3:48165877-48165877

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1559G>A; p.R520H; 3:48158961-48158961

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1431C>T; p.C477C; 3:48159347-48159347

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.109G>A; p.G37R; 3:48187839-48187839

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.208A>C; p.N70H; 3:48186742-48186742

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1327C>T; p.R443W; 3:48159451-48159451

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1336A>T; p.R446*; 3:48159442-48159442

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.566G>T; p.R189I; 3:48177972-48177972

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.654C>T; p.F218F; 3:48177884-48177884

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.654C>T; p.F218F; 3:48177884-48177884

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1236A>G; p.L412L; 3:48164393-48164393

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.809G>C; p.R270P; 3:48174405-48174405

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.109G>T; p.G37W; 3:48187839-48187839

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1517G>A; p.R506Q; 3:48159003-48159003

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1083T>A; p.S361S; 3:48165840-48165840

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.439G>A; p.E147K; 3:48180831-48180831

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1100C>G; p.S367C; 3:48165727-48165727

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1306G>C; p.E436Q; 3:48164323-48164323

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1112_1137del26; p.G371fs*11; 3:48165690-48165715

 ovarycarcinoma; serous_carcinomaDeletion - Frameshift

c.26A>C; p.H9P; 3:48187922-48187922

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.832C>T; p.R278*; 3:48174382-48174382

 prostatecarcinomaSubstitution - Nonsense

c.950C>T; p.S317F; 3:48167925-48167925

 skinmalignant_melanomaSubstitution - Missense

c.450G>A; p.K150K; 3:48180820-48180820

 skinmalignant_melanomaSubstitution - coding silent

c.450G>A; p.K150K; 3:48180820-48180820

 skinmalignant_melanomaSubstitution - coding silent

c.450G>A; p.K150K; 3:48180820-48180820

 skinmalignant_melanomaSubstitution - coding silent

c.1328G>A; p.R443Q; 3:48159450-48159450

 skinmalignant_melanomaSubstitution - Missense

c.1126C>T; p.L376F; 3:48165701-48165701

 skinmalignant_melanomaSubstitution - Missense

c.266C>T; p.P89L; 3:48184677-48184677

 skinmalignant_melanomaSubstitution - Missense

c.1450C>T; p.P484S; 3:48159070-48159070

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1223T>C; p.V408A; 3:48164406-48164406

 skinmalignant_melanomaSubstitution - Missense

c.591C>T; p.F197F; 3:48177947-48177947

 skinmalignant_melanomaSubstitution - coding silent

c.667G>A; p.D223N; 3:48177871-48177871

 skinmalignant_melanomaSubstitution - Missense

c.667G>A; p.D223N; 3:48177871-48177871

 skinmalignant_melanomaSubstitution - Missense

c.789C>T; p.S263S; 3:48174425-48174425

 skinmalignant_melanomaSubstitution - coding silent

c.760A>T; p.N254Y; 3:48174454-48174454

 skinmalignant_melanomaSubstitution - Missense

c.764G>A; p.R255Q; 3:48174450-48174450

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.501G>C; p.E167D; 3:48180769-48180769

 skinmalignant_melanomaSubstitution - Missense

c.654C>T; p.F218F; 3:48177884-48177884

 skinmalignant_melanomaSubstitution - coding silent

c.1096G>A; p.A366T; 3:48165731-48165731

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1274T>C; p.V425A; 3:48164355-48164355

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.339G>C; p.L113F; 3:48183019-48183019

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.279C>T; p.D93D; 3:48184664-48184664

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.878G>A; p.S293N; 3:48174336-48174336

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.248-9delT; p.?; 3:48184704-48184704

 stomachcarcinoma; diffuse_adenocarcinomaUnknown

c.1559G>A; p.R520H; 3:48158961-48158961

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1515C>A; p.S505R; 3:48159005-48159005

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1336A>T; p.R446*; 3:48159442-48159442

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.383A>G; p.D128G; 3:48182975-48182975

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.790C>G; p.L264V; 3:48174424-48174424

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.687T>G; p.N229K; 3:48177440-48177440

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.687T>G; p.N229K; 3:48177440-48177440

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.417G>T; p.E139D; 3:48182941-48182941

 urinary_tract; bladdercarcinomaSubstitution - Missense