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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

9846

Name

GAB2

Synonymous

GRB2-associated binding protein 2;GAB2;GRB2-associated binding protein 2

Definition

GRB2-associated-binding protein 2|Grb2-associated binder 2|growth factor receptor bound protein 2-associated protein 2|pp100

Position

11q14.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1175T>C; p.L392P; 11:78226497-78226497

 breastcarcinomaSubstitution - Missense

c.1056A>C; p.P352P; 11:78226616-78226616

 breastcarcinomaSubstitution - coding silent

c.1056A>C; p.P352P; 11:78226616-78226616

 breastcarcinomaSubstitution - coding silent

c.350G>A; p.G117D; 11:78280627-78280627

 breastcarcinomaSubstitution - Missense

c.1978G>C; p.E660Q; 11:78219325-78219325

 breastcarcinomaSubstitution - Missense

c.2016G>C; p.K672N; 11:78219287-78219287

 breastcarcinomaSubstitution - Missense

c.1061G>C; p.R354P; 11:78226611-78226611

 breastcarcinomaSubstitution - Missense

c.1024G>T; p.A342S; 11:78226648-78226648

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.1813C>T; p.P605S; 11:78220393-78220393

 central_nervous_system; braingliomaSubstitution - Missense

c.1056A>C; p.P352P; 11:78226616-78226616

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.111C>T; p.G37G; 11:78280866-78280866

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1561C>T; p.R521W; 11:78223418-78223418

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.195C>A; p.F65L; 11:78280782-78280782

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1181C>T; p.A394V; 11:78226491-78226491

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.241C>T; p.Q81*; 11:78280736-78280736

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.345C>A; p.I115I; 11:78280632-78280632

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.467G>A; p.R156H; 11:78250310-78250310

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1430T>A; p.I477N; 11:78223549-78223549

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1018A>T; p.T340S; 11:78226654-78226654

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1878C>T; p.P626P; 11:78220328-78220328

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1122A>G; p.P374P; 11:78226550-78226550

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1693C>T; p.R565C; 11:78221745-78221745

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1693C>T; p.R565C; 11:78221745-78221745

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1256C>T; p.A419V; 11:78225154-78225154

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.327C>T; p.V109V; 11:78280650-78280650

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.963C>A; p.L321L; 11:78226709-78226709

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.452A>G; p.H151R; 11:78250325-78250325

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.794C>A; p.T265N; 11:78226878-78226878

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.890C>T; p.T297M; 11:78226782-78226782

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2004A>G; p.S668S; 11:78219299-78219299

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1290T>C; p.V430V; 11:78225120-78225120

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.377-4T>G; p.?; 11:78250404-78250404

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.466C>T; p.R156C; 11:78250311-78250311

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisSubstitution - Missense

c.882C>T; p.T294T; 11:78226790-78226790

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.111C>T; p.G37G; 11:78280866-78280866

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.1461C>T; p.D487D; 11:78223518-78223518

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.1061G>C; p.R354P; 11:78226611-78226611

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1786G>A; p.V596I; 11:78220420-78220420

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1769C>G; p.P590R; 11:78220437-78220437

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1507A>T; p.S503C; 11:78223472-78223472

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.482C>T; p.P161L; 11:78250295-78250295

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1004delA; p.N335fs*5; 11:78226668-78226668

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1903G>A; p.V635I; 11:78219400-78219400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1100delG; p.G367fs*60; 11:78226572-78226572

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2004A>G; p.S668S; 11:78219299-78219299

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.320A>G; p.K107R; 11:78280657-78280657

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1602C>T; p.T534T; 11:78222161-78222161

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.855C>T; p.S285S; 11:78226817-78226817

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.33C>T; p.G11G; 11:78417688-78417688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.918C>T; p.F306F; 11:78226754-78226754

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.918C>T; p.F306F; 11:78226754-78226754

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.918C>T; p.F306F; 11:78226754-78226754

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1740C>T; p.S580S; 11:78221698-78221698

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1068_1069insC; p.K357fs*21; 11:78226603-78226604

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1229A>C; p.E410A; 11:78225181-78225181

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1900T>C; p.S634P; 11:78219403-78219403

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1900T>C; p.S634P; 11:78219403-78219403

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.481C>A; p.P161T; 11:78250296-78250296

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.277C>T; p.R93C; 11:78280700-78280700

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.481C>A; p.P161T; 11:78250296-78250296

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1072C>T; p.P358S; 11:78226600-78226600

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.831C>T; p.H277H; 11:78226841-78226841

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1902C>T; p.S634S; 11:78219401-78219401

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1490C>A; p.P497H; 11:78223489-78223489

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1507A>G; p.S503G; 11:78223472-78223472

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1859A>C; p.Q620P; 11:78220347-78220347

 livercarcinomaSubstitution - Missense

c.460C>T; p.R154*; 11:78250317-78250317

 livercarcinomaSubstitution - Nonsense

c.1167C>A; p.R389R; 11:78226505-78226505

 livercarcinomaSubstitution - coding silent

c.773A>G; p.N258S; 11:78226899-78226899

 livercarcinomaSubstitution - Missense

c.278G>A; p.R93H; 11:78280699-78280699

 livercarcinomaSubstitution - Missense

c.1494G>A; p.V498V; 11:78223485-78223485

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.307G>A; p.E103K; 11:78280670-78280670

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.482C>T; p.P161L; 11:78250295-78250295

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.1610A>G; p.D537G; 11:78222153-78222153

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.766C>A; p.R256R; 11:78226906-78226906

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1862C>A; p.P621Q; 11:78220344-78220344

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.903C>A; p.T301T; 11:78226769-78226769

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1240C>G; p.R414G; 11:78225170-78225170

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1384C>A; p.L462M; 11:78223595-78223595

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.154G>A; p.D52N; 11:78280823-78280823

 NSmalignant_melanomaSubstitution - Missense

c.951G>A; p.P317P; 11:78226721-78226721

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1043C>T; p.A348V; 11:78226629-78226629

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1499G>T; p.R500L; 11:78223480-78223480

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.237G>A; p.E79E; 11:78280740-78280740

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.499C>T; p.P167S; 11:78250278-78250278

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.414C>T; p.P138P; 11:78250363-78250363

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1949A>G; p.K650R; 11:78219354-78219354

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1558G>A; p.D520N; 11:78223421-78223421

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1509C>G; p.S503R; 11:78223470-78223470

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.829C>T; p.H277Y; 11:78226843-78226843

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1902C>G; p.S634S; 11:78219401-78219401

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.992C>A; p.T331N; 11:78226680-78226680

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1056A>C; p.P352P; 11:78226616-78226616

 pancreascarcinomaSubstitution - coding silent

c.881C>A; p.T294N; 11:78226791-78226791

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.684A>G; p.Q228Q; 11:78226988-78226988

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.684A>G; p.Q228Q; 11:78226988-78226988

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.684A>G; p.Q228Q; 11:78226988-78226988

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.1332C>G; p.D444E; 11:78223647-78223647

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1652G>A; p.R551K; 11:78222111-78222111

 prostateadenomaSubstitution - Missense

c.419C>T; p.S140F; 11:78250358-78250358

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1990G>A; p.V664M; 11:78219313-78219313

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.175C>T; p.R59W; 11:78280802-78280802

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1818G>A; p.K606K; 11:78220388-78220388

 skinmalignant_melanomaSubstitution - coding silent

c.912G>A; p.R304R; 11:78226760-78226760

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.367G>T; p.E123*; 11:78280610-78280610

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1735G>A; p.D579N; 11:78221703-78221703

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1021G>A; p.V341M; 11:78226651-78226651

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.930G>A; p.L310L; 11:78226742-78226742

 skinmalignant_melanomaSubstitution - coding silent

c.1534C>T; p.P512S; 11:78223445-78223445

 skinmalignant_melanomaSubstitution - Missense

c.387A>C; p.R129S; 11:78250390-78250390

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1593G>C; p.R531S; 11:78222170-78222170

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1068_1069insC; p.K357fs*21; 11:78226603-78226604

 skinmalignant_melanomaInsertion - Frameshift

c.1784C>T; p.P595L; 11:78220422-78220422

 skinmalignant_melanomaSubstitution - Missense

c.1348G>T; p.D450Y; 11:78223631-78223631

 skinmalignant_melanomaSubstitution - Missense

c.1514G>C; p.G505A; 11:78223465-78223465

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1214C>T; p.S405F; 11:78225196-78225196

 skinmalignant_melanomaSubstitution - Missense

c.1464A>G; p.S488S; 11:78223515-78223515

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2016G>T; p.K672N; 11:78219287-78219287

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1169A>G; p.N390S; 11:78226503-78226503

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1293C>T; p.G431G; 11:78225117-78225117

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1612G>A; p.E538K; 11:78222151-78222151

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1330G>T; p.D444Y; 11:78223649-78223649

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1392C>T; p.A464A; 11:78223587-78223587

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1282G>A; p.D428N; 11:78225128-78225128

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.143A>G; p.Y48C; 11:78280834-78280834

 urinary_tract; bladdercarcinomaSubstitution - Missense