Entrez Gene

Basic Information
Gene ID	9258
Name	MFHAS1
Synonymous	malignant fibrous histiocytoma amplified sequence 1;MFHAS1;malignant fibrous histiocytoma amplified sequence 1
Definition	MFH-amplified sequences with leucine-rich tandem repeats 1\|leucine rich repeat containing 65\|malignant fibrous histiocytoma-amplified sequence 1\|malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1\|malignant fibrous histioc
Position	8p23.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.2149G>C; p.E717Q; 8:8890910-8890910	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.2513G>A; p.G838D; 8:8890546-8890546	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2312C>T; p.A771V; 8:8890747-8890747	breast	carcinoma	Substitution - Missense
c.2693A>G; p.Y898C; 8:8890366-8890366	breast	carcinoma	Substitution - Missense
c.2573T>A; p.V858E; 8:8890486-8890486	breast	carcinoma	Substitution - Missense
c.197A>C; p.E66A; 8:8892862-8892862	central_nervous_system; brain	glioma	Substitution - Missense
c.1853delT; p.L618fs*64; 8:8891206-8891206	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.3101C>T; p.P1034L; 8:8797389-8797389	central_nervous_system; brain	glioma	Substitution - Missense
c.1453G>A; p.E485K; 8:8891606-8891606	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2203G>A; p.D735N; 8:8890856-8890856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2032C>T; p.R678*; 8:8891027-8891027	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1518C>A; p.T506T; 8:8891541-8891541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1693G>A; p.D565N; 8:8891366-8891366	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.827A>C; p.K276T; 8:8892232-8892232	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2313G>A; p.A771A; 8:8890746-8890746	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2935A>G; p.T979A; 8:8890124-8890124	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2942A>G; p.H981R; 8:8890117-8890117	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2551C>T; p.P851S; 8:8890508-8890508	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1896G>A; p.P632P; 8:8891163-8891163	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.951C>T; p.G317G; 8:8892108-8892108	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.397G>C; p.A133P; 8:8892662-8892662	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.387G>C; p.E129D; 8:8892672-8892672	haematopoietic_and_lymphoid_tissue; soft_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1144T>C; p.Y382H; 8:8891915-8891915	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1152C>G; p.V384V; 8:8891907-8891907	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.325C>T; p.L109F; 8:8892734-8892734	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.2249A>G; p.H750R; 8:8890810-8890810	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1625G>T; p.C542F; 8:8891434-8891434	kidney	other; neoplasm	Substitution - Missense
c.2645T>C; p.I882T; 8:8890414-8890414	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3001G>C; p.E1001Q; 8:8797489-8797489	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1194A>T; p.E398D; 8:8891865-8891865	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.2341C>A; p.R781R; 8:8890718-8890718	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3155A>G; p.Q1052R; 8:8786026-8786026	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2192C>A; p.T731N; 8:8890867-8890867	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2999-1G>T; p.?; 8:8797492-8797492	kidney	carcinoma; papillary_renal_cell_carcinoma	Unknown
c.3101C>A; p.P1034Q; 8:8797389-8797389	kidney	other; neoplasm	Substitution - Missense
c.642C>G; p.N214K; 8:8892417-8892417	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.308C>T; p.P103L; 8:8892751-8892751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1692C>T; p.H564H; 8:8891367-8891367	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.102T>C; p.L34L; 8:8892957-8892957	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2815G>A; p.D939N; 8:8890244-8890244	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.985A>G; p.N329D; 8:8892074-8892074	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1369G>A; p.G457S; 8:8891690-8891690	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1369G>A; p.G457S; 8:8891690-8891690	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1897C>T; p.R633C; 8:8891162-8891162	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1897C>T; p.R633C; 8:8891162-8891162	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.565G>T; p.D189Y; 8:8892494-8892494	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1910G>A; p.R637H; 8:8891149-8891149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2961C>T; p.C987C; 8:8890098-8890098	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1589C>T; p.A530V; 8:8891470-8891470	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2937C>G; p.T979T; 8:8890122-8890122	large_intestine	NS	Substitution - coding silent
c.1494C>T; p.Y498Y; 8:8891565-8891565	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2175C>T; p.H725H; 8:8890884-8890884	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1717G>A; p.A573T; 8:8891342-8891342	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1675G>A; p.A559T; 8:8891384-8891384	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2311G>A; p.A771T; 8:8890748-8890748	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.40C>T; p.L14L; 8:8893019-8893019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1529G>A; p.R510H; 8:8891530-8891530	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1529G>A; p.R510H; 8:8891530-8891530	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.923T>A; p.L308H; 8:8892136-8892136	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1529G>A; p.R510H; 8:8891530-8891530	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.901C>T; p.L301F; 8:8892158-8892158	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.594G>A; p.R198R; 8:8892465-8892465	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1587C>T; p.H529H; 8:8891472-8891472	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1382C>T; p.T461I; 8:8891677-8891677	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1382C>T; p.T461I; 8:8891677-8891677	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1898G>A; p.R633H; 8:8891161-8891161	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1898G>A; p.R633H; 8:8891161-8891161	large_intestine; colon	NS	Substitution - Missense
c.1181C>A; p.A394D; 8:8891878-8891878	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2740T>C; p.F914L; 8:8890319-8890319	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.849C>T; p.N283N; 8:8892210-8892210	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2131G>A; p.G711S; 8:8890928-8890928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1277G>A; p.R426H; 8:8891782-8891782	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1248G>A; p.G416G; 8:8891811-8891811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.804G>C; p.Q268H; 8:8892255-8892255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.840C>G; p.L280L; 8:8892219-8892219	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.840C>G; p.L280L; 8:8892219-8892219	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2937C>A; p.T979T; 8:8890122-8890122	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2756A>G; p.Y919C; 8:8890303-8890303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1133_1137delTCCAG; p.I378fs*39; 8:8891922-8891926	liver	carcinoma	Deletion - Frameshift
c.2673A>T; p.P891P; 8:8890386-8890386	liver	carcinoma	Substitution - coding silent
c.2930A>G; p.H977R; 8:8890129-8890129	liver	carcinoma	Substitution - Missense
c.1116C>T; p.I372I; 8:8891943-8891943	liver	carcinoma	Substitution - coding silent
c.1116C>T; p.I372I; 8:8891943-8891943	liver	carcinoma	Substitution - coding silent
c.2041C>A; p.L681I; 8:8891018-8891018	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1654C>T; p.L552L; 8:8891405-8891405	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1570G>T; p.G524W; 8:8891489-8891489	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2093A>G; p.D698G; 8:8890966-8890966	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2908C>A; p.L970I; 8:8890151-8890151	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2995C>G; p.P999A; 8:8890064-8890064	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1696G>A; p.A566T; 8:8891363-8891363	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2324C>G; p.P775R; 8:8890735-8890735	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1784A>G; p.Y595C; 8:8891275-8891275	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.500T>C; p.F167S; 8:8892559-8892559	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2908_2909delCT; p.L970fs*16; 8:8890150-8890151	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1984T>G; p.S662A; 8:8891075-8891075	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.506G>T; p.R169L; 8:8892553-8892553	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2240T>A; p.L747*; 8:8890819-8890819	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Nonsense
c.2240T>A; p.L747*; 8:8890819-8890819	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Nonsense
c.2240T>A; p.L747*; 8:8890819-8890819	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.2920C>T; p.P974S; 8:8890139-8890139	prostate	carcinoma	Substitution - Missense
c.600G>T; p.L200L; 8:8892459-8892459	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1848C>G; p.H616Q; 8:8891211-8891211	skin	malignant_melanoma	Substitution - Missense
c.3050C>T; p.P1017L; 8:8797440-8797440	skin	malignant_melanoma	Substitution - Missense
c.636C>T; p.S212S; 8:8892423-8892423	skin	malignant_melanoma	Substitution - coding silent
c.1075G>A; p.D359N; 8:8891984-8891984	skin	malignant_melanoma	Substitution - Missense
c.1239C>T; p.L413L; 8:8891820-8891820	skin	malignant_melanoma	Substitution - coding silent
c.1722_1723GG>AA; p.V575M; 8:8891336-8891337	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2801G>T; p.G934V; 8:8890258-8890258	skin	malignant_melanoma	Substitution - Missense
c.2801G>T; p.G934V; 8:8890258-8890258	skin	malignant_melanoma	Substitution - Missense
c.1452T>G; p.Y484*; 8:8891607-8891607	skin	malignant_melanoma	Substitution - Nonsense
c.3096C>T; p.P1032P; 8:8797394-8797394	skin	malignant_melanoma	Substitution - coding silent
c.3044T>A; p.I1015N; 8:8797446-8797446	skin	malignant_melanoma	Substitution - Missense
c.1752C>T; p.F584F; 8:8891307-8891307	skin	malignant_melanoma	Substitution - coding silent
c.1861C>T; p.L621F; 8:8891198-8891198	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1810C>T; p.R604*; 8:8891249-8891249	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1597T>C; p.C533R; 8:8891462-8891462	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.961C>T; p.L321F; 8:8892098-8892098	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2686G>A; p.A896T; 8:8890373-8890373	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2638T>G; p.L880V; 8:8890421-8890421	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2161G>A; p.A721T; 8:8890898-8890898	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3102G>A; p.P1034P; 8:8797388-8797388	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1415G>A; p.R472Q; 8:8891644-8891644	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1420A>G; p.I474V; 8:8891639-8891639	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2059G>A; p.A687T; 8:8891000-8891000	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2770C>G; p.P924A; 8:8890289-8890289	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3067C>T; p.R1023*; 8:8797423-8797423	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1768A>T; p.S590C; 8:8891291-8891291	thyroid	other; neoplasm	Substitution - Missense
c.1744C>A; p.R582R; 8:8891315-8891315	thyroid	other; neoplasm	Substitution - coding silent
c.1769G>A; p.S590N; 8:8891290-8891290	thyroid	other; neoplasm	Substitution - Missense
c.1550G>T; p.G517V; 8:8891509-8891509	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1550G>T; p.G517V; 8:8891509-8891509	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.420C>T; p.L140L; 8:8892639-8892639	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1798G>C; p.D600H; 8:8891261-8891261	urinary_tract; bladder	carcinoma	Substitution - Missense
c.705T>G; p.S235R; 8:8892354-8892354	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1014C>T; p.I338I; 8:8892045-8892045	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.279C>G; p.V93V; 8:8892780-8892780	urinary_tract; bladder	carcinoma	Substitution - coding silent

Oncogene database

COSMIC confirmed somatic mutation [Top]

Bioinformatics and cancer genomics links

Bioinformatics centers

Bioinformatics centers

Welcome to Bioinfo-MinZhao!