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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

898

Name

CCNE1

Synonymous

cyclin E1;CCNE1;cyclin E1

Definition

G1/S-specific cyclin-E1|cyclin E variant ex5del|cyclin E variant ex7del|cyclin Es|cyclin Et

Position

19q12

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.775C>A; p.L259I; 19:29822065-29822065

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.775C>A; p.L259I; 19:29822065-29822065

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.929C>A; p.S310Y; 19:29822328-29822328

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.516C>G; p.F172L; 19:29820755-29820755

 breastcarcinomaSubstitution - Missense

c.1095C>T; p.D365D; 19:29822588-29822588

 breastcarcinomaSubstitution - coding silent

c.1057G>A; p.A353T; 19:29822550-29822550

 breastcarcinomaSubstitution - Missense

c.1089C>G; p.H363Q; 19:29822582-29822582

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.831G>C; p.Q277H; 19:29822121-29822121

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.143A>C; p.K48T; 19:29813000-29813000

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.516C>A; p.F172L; 19:29820755-29820755

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.534G>A; p.A178A; 19:29820773-29820773

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.191A>T; p.N64I; 19:29817147-29817147

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.111+1G>A; p.?; 19:29812777-29812777

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.857T>C; p.V286A; 19:29822256-29822256

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.87G>A; p.R29R; 19:29812752-29812752

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1196G>T; p.S399I; 19:29823740-29823740

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.953-9T>C; p.?; 19:29822437-29822437

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.64G>C; p.A22P; 19:29812729-29812729

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.355A>G; p.I119V; 19:29817434-29817434

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.65C>T; p.A22V; 19:29812730-29812730

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.819A>C; p.Q273H; 19:29822109-29822109

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.144A>C; p.K48N; 19:29813001-29813001

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.641C>T; p.A214V; 19:29821753-29821753

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1229C>T; p.A410V; 19:29823773-29823773

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.534G>A; p.A178A; 19:29820773-29820773

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1006A>G; p.M336V; 19:29822499-29822499

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1220C>T; p.P407L; 19:29823764-29823764

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1220C>T; p.P407L; 19:29823764-29823764

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1220C>T; p.P407L; 19:29823764-29823764

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.283C>A; p.R95R; 19:29817239-29817239

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.285G>T; p.R95R; 19:29817241-29817241

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.998C>T; p.P333L; 19:29822491-29822491

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1188G>A; p.P396P; 19:29823732-29823732

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.718C>T; p.R240C; 19:29822008-29822008

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1121G>A; p.R374Q; 19:29823665-29823665

 livercarcinomaSubstitution - Missense

c.75G>T; p.S25S; 19:29812740-29812740

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1111G>T; p.D371Y; 19:29823655-29823655

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1156G>T; p.A386S; 19:29823700-29823700

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.138G>T; p.M46I; 19:29812995-29812995

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.883C>A; p.P295T; 19:29822282-29822282

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.975G>A; p.E325E; 19:29822468-29822468

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1084A>G; p.T362A; 19:29822577-29822577

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.469G>C; p.E157Q; 19:29820708-29820708

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.647T>A; p.V216E; 19:29821759-29821759

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.462+1G>T; p.?; 19:29817542-29817542

 lung; right_upper_lobecarcinoma; adenocarcinomaUnknown

c.1228G>T; p.A410S; 19:29823772-29823772

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1154_1155GG>CT; p.R385T; 19:29823698-29823699

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.181-2A>G; p.?; 19:29817135-29817135

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.1007T>C; p.M336T; 19:29822500-29822500

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.120G>A; p.Q40Q; 19:29812977-29812977

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1152T>A; p.N384K; 19:29823696-29823696

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.283C>T; p.R95W; 19:29817239-29817239

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.488delG; p.E164fs*21; 19:29820727-29820727

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.520G>C; p.D174H; 19:29820759-29820759

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.980G>A; p.C327Y; 19:29822473-29822473

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.90G>C; p.K30N; 19:29812755-29812755

 oesophaguscarcinomaSubstitution - Missense

c.1003G>T; p.A335S; 19:29822496-29822496

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1229C>T; p.A410V; 19:29823773-29823773

 prostateadenomaSubstitution - Missense

c.834T>G; p.I278M; 19:29822124-29822124

 skin; earmalignant_melanomaSubstitution - Missense

c.823T>C; p.F275L; 19:29822113-29822113

 skinmalignant_melanomaSubstitution - Missense

c.1134C>T; p.A378A; 19:29823678-29823678

 skinmalignant_melanomaSubstitution - coding silent

c.916C>T; p.H306Y; 19:29822315-29822315

 skinmalignant_melanomaSubstitution - Missense

c.48G>A; p.M16I; 19:29812713-29812713

 skinmalignant_melanomaSubstitution - Missense

c.1002T>C; p.F334F; 19:29822495-29822495

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.905C>T; p.S302L; 19:29822304-29822304

 skinmalignant_melanomaSubstitution - Missense

c.881T>C; p.F294S; 19:29822280-29822280

 skinmalignant_melanomaSubstitution - Missense

c.67G>C; p.E23Q; 19:29812732-29812732

 skinmalignant_melanomaSubstitution - Missense

c.812C>T; p.P271L; 19:29822102-29822102

 skinmalignant_melanomaSubstitution - Missense

c.966C>T; p.C322C; 19:29822459-29822459

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.821T>C; p.I274T; 19:29822111-29822111

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1053C>T; p.G351G; 19:29822546-29822546

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.434G>A; p.R145Q; 19:29817513-29817513

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.424C>T; p.P142S; 19:29817503-29817503

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1008G>T; p.M336I; 19:29822501-29822501

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1057G>A; p.A353T; 19:29822550-29822550

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.532G>A; p.A178T; 19:29820771-29820771

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1183A>C; p.T395P; 19:29823727-29823727

 thyroidother; neoplasmSubstitution - Missense

c.68A>G; p.E23G; 19:29812733-29812733

 thyroidother; neoplasmSubstitution - Missense

c.1183A>C; p.T395P; 19:29823727-29823727

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.283C>T; p.R95W; 19:29817239-29817239

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense