ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

8878

Name

SQSTM1

Synonymous

sequestosome 1;SQSTM1;sequestosome 1

Definition

EBI3-associated protein of 60 kDa|EBI3-associated protein p60|EBIAP|oxidative stress induced like|phosphotyrosine independent ligand for the Lck SH2 domain p62|phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa|sequestosome-1|ubiquitin-bi

Position

5q35

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.662C>T; p.T221M; 5:179824312-179824312

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.494A>G; p.K165R; 5:179824050-179824050

 breastcarcinomaSubstitution - Missense

c.969+2C>G; p.?; 5:179833248-179833248

 breastcarcinomaUnknown

c.321_328delGGACCACC; p.D108fs*42; 5:179823877-179823884

 breastcarcinomaDeletion - Frameshift

c.1260G>T; p.K420N; 5:179836530-179836530

 breastcarcinomaSubstitution - Missense

c.1043C>T; p.P348L; 5:179833660-179833660

 breastcarcinomaSubstitution - Missense

c.1230C>T; p.G410G; 5:179836500-179836500

 breastcarcinomaSubstitution - coding silent

c.5C>T; p.A2V; 5:179820941-179820941

 central_nervous_system; braingliomaSubstitution - Missense

c.1272C>T; p.I424I; 5:179836542-179836542

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.286C>T; p.R96*; 5:179823038-179823038

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.404T>C; p.V135A; 5:179823960-179823960

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.426C>T; p.C142C; 5:179823982-179823982

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.626G>A; p.R209H; 5:179824276-179824276

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.427A>T; p.S143C; 5:179823983-179823983

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.356G>A; p.R119H; 5:179823912-179823912

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1A>G; p.M1V; 5:179820937-179820937

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.98C>T; p.A33V; 5:179821034-179821034

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.396T>C; p.N132N; 5:179823952-179823952

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.24C>A; p.A8A; 5:179820960-179820960

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.450G>A; p.L150L; 5:179824006-179824006

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.481C>T; p.R161W; 5:179824037-179824037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.481C>T; p.R161W; 5:179824037-179824037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1277C>T; p.A426V; 5:179836547-179836547

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.418T>C; p.Y140H; 5:179823974-179823974

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.15C>T; p.T5T; 5:179820951-179820951

 livercarcinomaSubstitution - coding silent

c.15C>T; p.T5T; 5:179820951-179820951

 livercarcinomaSubstitution - coding silent

c.922G>C; p.A308P; 5:179833199-179833199

 livercarcinomaSubstitution - Missense

c.970-1G>A; p.?; 5:179833586-179833586

 livercarcinoma; hepatocellular_carcinomaUnknown

c.970-1G>A; p.?; 5:179833586-179833586

 livercarcinoma; hepatocellular_carcinomaUnknown

c.614A>G; p.N205S; 5:179824264-179824264

 livercarcinomaSubstitution - Missense

c.593G>A; p.W198*; 5:179824243-179824243

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.329G>T; p.R110L; 5:179823885-179823885

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.829A>G; p.S277G; 5:179833106-179833106

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.334C>T; p.P112S; 5:179823890-179823890

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.233C>T; p.S78F; 5:179822985-179822985

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.226G>T; p.A76S; 5:179822978-179822978

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.277G>T; p.D93Y; 5:179823029-179823029

 NSNSSubstitution - Missense

c.1138G>A; p.A380T; 5:179833755-179833755

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.450G>A; p.L150L; 5:179824006-179824006

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.27C>T; p.Y9Y; 5:179820963-179820963

 pancreascarcinomaSubstitution - coding silent

c.286C>A; p.R96R; 5:179823038-179823038

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.581G>A; p.G194E; 5:179824231-179824231

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.1033G>A; p.E345K; 5:179833650-179833650

 skinmalignant_melanomaSubstitution - Missense

c.724G>A; p.E242K; 5:179825196-179825196

 skinmalignant_melanomaSubstitution - Missense

c.375T>A; p.N125K; 5:179823931-179823931

 skinmalignant_melanomaSubstitution - Missense

c.611G>A; p.G204E; 5:179824261-179824261

 skinmalignant_melanomaSubstitution - Missense

c.1273G>A; p.G425R; 5:179836543-179836543

 skinmalignant_melanomaSubstitution - Missense

c.1273G>A; p.G425R; 5:179836543-179836543

 skinmalignant_melanomaSubstitution - Missense

c.1078G>A; p.E360K; 5:179833695-179833695

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.298A>G; p.K100E; 5:179823050-179823050

 skin; neckmalignant_melanomaSubstitution - Missense

c.712A>G; p.K238E; 5:179825184-179825184

 soft_tissue; fibrous_tissue_and_uncertain_ogastrointestinal_stromal_tumourSubstitution - Missense

c.962G>A; p.R321H; 5:179833239-179833239

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.262T>C; p.S88P; 5:179823014-179823014

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.763G>A; p.V255I; 5:179833040-179833040

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1262A>G; p.N421S; 5:179836532-179836532

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1317G>A; p.P439P; 5:179836587-179836587

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.602G>A; p.G201D; 5:179824252-179824252

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.328C>T; p.R110C; 5:179823884-179823884

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.287G>A; p.R96Q; 5:179823039-179823039

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.876C>T; p.D292D; 5:179833153-179833153

 thyroidother; neoplasmSubstitution - coding silent

c.454A>T; p.S152C; 5:179824010-179824010

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1282C>T; p.L428L; 5:179836552-179836552

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1317G>A; p.P439P; 5:179836587-179836587

 urinary_tract; bladdercarcinomaSubstitution - coding silent