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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

8837

Name

CFLAR

Synonymous

CASP8 and FADD-like apoptosis regulator;CFLAR;CASP8 and FADD-like apoptosis regulator

Definition

FADD-like antiapoptotic molecule 1|MACH-related inducer of toxicity|caspase homolog|caspase-eight-related protein|caspase-like apoptosis regulatory protein|caspase-related inducer of apoptosis|cellular FLICE-like inhibitory protein|inhibitor of FLICE|usur

Position

2q33-q34

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1093G>T; p.G365C; 2:201160731-201160731

 breastcarcinomaSubstitution - Missense

c.288G>T; p.L96L; 2:201133035-201133035

 breastcarcinomaSubstitution - coding silent

c.565G>T; p.A189S; 2:201140398-201140398

 breastcarcinomaSubstitution - Missense

c.934C>A; p.L312M; 2:201160572-201160572

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.931G>A; p.V311I; 2:201160569-201160569

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.653G>A; p.G218D; 2:201145424-201145424

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1443A>G; p.*481*; 2:201163973-201163973

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.771C>T; p.I257I; 2:201149813-201149813

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.240G>A; p.E80E; 2:201130105-201130105

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>A; p.P197T; 2:201140422-201140422

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1028A>G; p.D343G; 2:201160666-201160666

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.363C>T; p.G121G; 2:201133110-201133110

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1143G>T; p.K381N; 2:201160781-201160781

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.877C>A; p.L293I; 2:201160515-201160515

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.33A>G; p.E11E; 2:201129898-201129898

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.198C>T; p.D66D; 2:201130063-201130063

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.128T>C; p.I43T; 2:201129993-201129993

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.123G>C; p.L41L; 2:201129988-201129988

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.653G>A; p.G218D; 2:201145424-201145424

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.568A>G; p.I190V; 2:201140401-201140401

 livercarcinomaSubstitution - Missense

c.568A>G; p.I190V; 2:201140401-201140401

 livercarcinomaSubstitution - Missense

c.1264C>T; p.L422L; 2:201160902-201160902

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1171G>T; p.G391W; 2:201160809-201160809

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1249C>A; p.H417N; 2:201160887-201160887

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.162C>G; p.D54E; 2:201130027-201130027

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1031C>T; p.S344L; 2:201160669-201160669

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.45A>C; p.T15T; 2:201129910-201129910

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1293G>T; p.L431L; 2:201160931-201160931

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.83T>C; p.V28A; 2:201129948-201129948

 skinmalignant_melanomaSubstitution - Missense

c.1159G>C; p.A387P; 2:201160797-201160797

 skinmalignant_melanomaSubstitution - Missense

c.972G>A; p.V324V; 2:201160610-201160610

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1419G>A; p.K473K; 2:201163949-201163949

 skinmalignant_melanomaSubstitution - coding silent

c.1116C>T; p.L372L; 2:201160754-201160754

 skinmalignant_melanomaSubstitution - coding silent

c.442C>T; p.Q148*; 2:201136026-201136026

 skinmalignant_melanomaSubstitution - Nonsense

c.1188C>T; p.H396H; 2:201160826-201160826

 skinmalignant_melanomaSubstitution - coding silent

c.501A>T; p.K167N; 2:201136085-201136085

 skinmalignant_melanomaSubstitution - Missense

c.31G>A; p.E11K; 2:201129896-201129896

 skinmalignant_melanomaSubstitution - Missense

c.355T>G; p.Y119D; 2:201133102-201133102

 skinmalignant_melanomaSubstitution - Missense

c.943C>A; p.R315R; 2:201160581-201160581

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.877C>G; p.L293V; 2:201160515-201160515

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.957G>A; p.Q319Q; 2:201160595-201160595

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.409G>A; p.E137K; 2:201135993-201135993

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1249C>T; p.H417Y; 2:201160887-201160887

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1249C>T; p.H417Y; 2:201160887-201160887

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1340A>G; p.N447S; 2:201163870-201163870

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1340A>G; p.N447S; 2:201163870-201163870

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense