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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

864

Name

RUNX3

Synonymous

runt-related transcription factor 3;RUNX3;runt-related transcription factor 3

Definition

CBF-alpha-3|PEA2 alpha C|PEA2-alpha C|PEBP2 alpha C|PEBP2-alpha C|SL3-3 enhancer factor 1 alpha C subunit|SL3/AKV core-binding factor alpha C subunit|acute myeloid leukemia 2 protein|acute myeloid leukemia gene 2|core-binding factor subunit alpha-3|core-b

Position

1p36

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.898A>C; p.T300P; 1:24902472-24902472

 breastcarcinomaSubstitution - Missense

c.879C>T; p.S293S; 1:24902491-24902491

 breastcarcinomaSubstitution - coding silent

c.244C>A; p.H82N; 1:24929625-24929625

 breastcarcinomaSubstitution - Missense

c.647G>A; p.R216Q; 1:24907315-24907315

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.614G>A; p.R205H; 1:24907348-24907348

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.980C>T; p.P327L; 1:24902390-24902390

 central_nervous_system; braingliomaSubstitution - Missense

c.1170C>T; p.A390A; 1:24902200-24902200

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1209G>A; p.T403T; 1:24902161-24902161

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1197G>A; p.T399T; 1:24902173-24902173

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.947C>T; p.P316L; 1:24902423-24902423

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.274G>T; p.A92S; 1:24929595-24929595

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.550C>T; p.R184W; 1:24907412-24907412

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.222C>T; p.F74F; 1:24929647-24929647

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1084G>A; p.A362T; 1:24902286-24902286

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.145C>A; p.R49R; 1:24929724-24929724

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.172G>C; p.V58L; 1:24929697-24929697

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.243G>T; p.S81S; 1:24929626-24929626

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1161C>T; p.G387G; 1:24902209-24902209

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.79_81delGGC; p.G27delG; 1:24929788-24929790

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.235C>T; p.L79L; 1:24929634-24929634

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1059C>T; p.G353G; 1:24902311-24902311

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.591C>T; p.R197R; 1:24907371-24907371

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1170C>T; p.A390A; 1:24902200-24902200

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.378C>T; p.A126A; 1:24927635-24927635

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1210C>A; p.P404T; 1:24902160-24902160

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.361C>T; p.L121L; 1:24927652-24927652

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.13G>A; p.V5I; 1:24929856-24929856

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.960C>T; p.S320S; 1:24902410-24902410

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.502C>T; p.R168*; 1:24919282-24919282

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.502C>T; p.R168*; 1:24919282-24919282

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.502C>T; p.R168*; 1:24919282-24919282

 large_intestine; coloncarcinomaSubstitution - Nonsense

c.502C>T; p.R168*; 1:24919282-24919282

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.533G>A; p.R178Q; 1:24919251-24919251

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.518C>T; p.T173I; 1:24919266-24919266

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.847_848AC>CA; p.T283Q; 1:24902522-24902523

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.830C>T; p.A277V; 1:24902540-24902540

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.800G>T; p.R267M; 1:24902570-24902570

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.943delG; p.A315fs*63; 1:24902427-24902427

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1215C>T; p.G405G; 1:24902155-24902155

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.613C>T; p.R205C; 1:24907349-24907349

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.613C>T; p.R205C; 1:24907349-24907349

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.526G>A; p.G176R; 1:24919258-24919258

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.826G>A; p.A276T; 1:24902544-24902544

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.844G>A; p.A282T; 1:24902526-24902526

 livercarcinomaSubstitution - Missense

c.795C>G; p.D265E; 1:24902575-24902575

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.428G>T; p.R143L; 1:24927585-24927585

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.598delG; p.D200fs*9; 1:24907364-24907364

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.608G>T; p.R203L; 1:24907354-24907354

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.729C>G; p.S243S; 1:24902641-24902641

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.465T>A; p.T155T; 1:24919319-24919319

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.330G>T; p.M110I; 1:24927683-24927683

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.762G>T; p.T254T; 1:24902608-24902608

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.330G>T; p.M110I; 1:24927683-24927683

 lungcarcinoma; bronchioloalveolar_adenocarcinomaSubstitution - Missense

c.844G>T; p.A282S; 1:24902526-24902526

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.276C>A; p.A92A; 1:24929593-24929593

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.700C>T; p.Q234*; 1:24907262-24907262

 lungcarcinoma; small_cell_carcinomaSubstitution - Nonsense

c.340G>A; p.D114N; 1:24927673-24927673

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.427C>T; p.R143C; 1:24927586-24927586

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.894G>A; p.P298P; 1:24902476-24902476

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.375G>T; p.S125S; 1:24927638-24927638

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.629C>T; p.P210L; 1:24907333-24907333

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.731A>C; p.D244A; 1:24902639-24902639

 ovaryother; neoplasmSubstitution - Missense

c.520G>A; p.V174M; 1:24919264-24919264

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1236G>T; p.W412C; 1:24902134-24902134

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.926C>T; p.P309L; 1:24902444-24902444

 pancreascarcinomaSubstitution - Missense

c.776C>T; p.T259M; 1:24902594-24902594

 pancreascarcinomaSubstitution - Missense

c.748C>T; p.R250C; 1:24902622-24902622

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1135_1136CC>TT; p.P379F; 1:24902234-24902235

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.694C>T; p.P232S; 1:24907268-24907268

 skin; extremitymalignant_melanomaSubstitution - Missense

c.376G>A; p.A126T; 1:24927637-24927637

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.983C>T; p.S328F; 1:24902387-24902387

 skinmalignant_melanomaSubstitution - Missense

c.819C>T; p.A273A; 1:24902551-24902551

 skinmalignant_melanomaSubstitution - coding silent

c.659G>A; p.S220N; 1:24907303-24907303

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.353_354CC>TT; p.S118F; 1:24927659-24927660

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.854C>T; p.S285L; 1:24902516-24902516

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.729C>T; p.S243S; 1:24902641-24902641

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.532C>T; p.R178W; 1:24919252-24919252

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.345G>T; p.E115D; 1:24927668-24927668

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.301G>A; p.V101M; 1:24927712-24927712

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.437G>C; p.R146P; 1:24927576-24927576

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.525C>T; p.D175D; 1:24919259-24919259

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.623T>G; p.V208G; 1:24907339-24907339

 thyroidother; neoplasmSubstitution - Missense