Entrez Gene

Basic Information
Gene ID	8626
Name	TP63
Synonymous	tumor protein p63;TP63;tumor protein p63
Definition	CUSP\|amplified in squamous cell carcinoma\|chronic ulcerative stomatitis protein\|keratinocyte transcription factor KET\|transformation-related protein 63\|tumor protein 63\|tumor protein p53-competing protein\|tumor protein p63 deltaN isoform delta
Position	3q28
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1883T>A; p.V628E; 3:189894342-189894342	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1273C>T; p.Q425*; 3:189872919-189872919	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.274A>C; p.S92R; 3:189738724-189738724	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1121C>T; p.T374M; 3:189868708-189868708	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.193C>T; p.P65S; 3:189738643-189738643	breast	carcinoma	Substitution - Missense
c.1889C>G; p.S630C; 3:189894348-189894348	breast	carcinoma	Substitution - Missense
c.762C>T; p.N254N; 3:189864414-189864414	breast	carcinoma	Substitution - coding silent
c.1713C>T; p.T571T; 3:189890849-189890849	breast	carcinoma	Substitution - coding silent
c.1398G>A; p.L466L; 3:189886442-189886442	breast	carcinoma	Substitution - coding silent
c.566C>T; p.S189L; 3:189808513-189808513	breast	carcinoma	Substitution - Missense
c.1651A>G; p.S551G; 3:189889483-189889483	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1959A>C; p.P653P; 3:189894418-189894418	breast	carcinoma	Substitution - coding silent
c.1474C>T; p.P492S; 3:189886518-189886518	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.203C>T; p.S68L; 3:189738653-189738653	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1177C>T; p.R393*; 3:189869371-189869371	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.677G>A; p.R226H; 3:189864329-189864329	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1635A>G; p.T545T; 3:189889467-189889467	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.581A>C; p.Y194S; 3:189864233-189864233	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.679G>A; p.A227T; 3:189864331-189864331	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.707A>G; p.H236R; 3:189864359-189864359	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1028G>T; p.R343L; 3:189868615-189868615	central_nervous_system; brain	glioma	Substitution - Missense
c.1130-1G>C; p.?; 3:189869323-189869323	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Unknown
c.987C>A; p.T329T; 3:189867937-189867937	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.335C>T; p.T112M; 3:189808282-189808282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.522G>A; p.P174P; 3:189808469-189808469	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.66C>T; p.F22F; 3:189737743-189737743	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.66C>T; p.F22F; 3:189737743-189737743	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.469G>T; p.D157Y; 3:189808416-189808416	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1173G>T; p.K391N; 3:189869367-189869367	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.110G>A; p.R37Q; 3:189737787-189737787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1787C>T; p.A596V; 3:189894246-189894246	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1909C>T; p.R637C; 3:189894368-189894368	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1128C>T; p.R376R; 3:189868715-189868715	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1010G>T; p.R337L; 3:189868597-189868597	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1581C>G; p.P527P; 3:189889413-189889413	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1465G>A; p.A489T; 3:189886509-189886509	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.453G>A; p.Q151Q; 3:189808400-189808400	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.448G>A; p.A150T; 3:189808395-189808395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1748A>T; p.D583V; 3:189894207-189894207	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.431C>T; p.T144M; 3:189808378-189808378	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1013G>A; p.R338H; 3:189868600-189868600	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1780C>T; p.R594*; 3:189894239-189894239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1780C>T; p.R594*; 3:189894239-189894239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.796C>T; p.R266*; 3:189866711-189866711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1083G>A; p.K361K; 3:189868670-189868670	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1788G>A; p.A596A; 3:189894247-189894247	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.485C>T; p.S162L; 3:189808432-189808432	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1061C>T; p.A354V; 3:189868648-189868648	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.709G>A; p.V237I; 3:189864361-189864361	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.709G>A; p.V237I; 3:189864361-189864361	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.709G>A; p.V237I; 3:189864361-189864361	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1211C>A; p.P404Q; 3:189869405-189869405	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Substitution - Missense
c.1136G>A; p.R379H; 3:189869330-189869330	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1616C>T; p.P539L; 3:189889448-189889448	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.72A>G; p.E24E; 3:189737749-189737749	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1127G>A; p.R376H; 3:189868714-189868714	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.60G>A; p.Q20Q; 3:189631575-189631575	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1657T>C; p.L553L; 3:189890793-189890793	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1458G>A; p.Q486Q; 3:189886502-189886502	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1107G>C; p.K369N; 3:189868694-189868694	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1788G>C; p.A596A; 3:189894247-189894247	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1213-1G>T; p.?; 3:189872858-189872858	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1094C>T; p.S365L; 3:189868681-189868681	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.731G>A; p.C244Y; 3:189864383-189864383	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.522G>A; p.P174P; 3:189808469-189808469	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1409A>G; p.N470S; 3:189886453-189886453	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2007_2008CA>AT; p.R669>?; 3:189894466-189894467	large_intestine; colon	carcinoma; adenocarcinoma	Complex
c.985A>G; p.T329A; 3:189867935-189867935	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1129C>T; p.P377S; 3:189868716-189868716	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.752G>A; p.R251H; 3:189864404-189864404	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.987C>T; p.T329T; 3:189867937-189867937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1062G>A; p.A354A; 3:189868649-189868649	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.806G>A; p.G269E; 3:189866721-189866721	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1253A>G; p.K418R; 3:189872899-189872899	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.336G>A; p.T112T; 3:189808283-189808283	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.441G>A; p.S147S; 3:189808388-189808388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.415G>A; p.A139T; 3:189808362-189808362	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1964G>A; p.R655Q; 3:189894423-189894423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1993A>G; p.M665V; 3:189894452-189894452	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.399C>T; p.P133P; 3:189808346-189808346	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.818C>A; p.A273D; 3:189866733-189866733	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.G127S; 3:189808326-189808326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.512A>G; p.Y171C; 3:189808459-189808459	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.807G>A; p.G269G; 3:189866722-189866722	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.321G>A; p.M107I; 3:189738771-189738771	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.447C>T; p.Y149Y; 3:189808394-189808394	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1656C>A; p.F552L; 3:189890792-189890792	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1550A>G; p.N517S; 3:189889382-189889382	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1625C>T; p.P542L; 3:189889457-189889457	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.859C>T; p.L287L; 3:189866774-189866774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1615delC; p.P540fs*14; 3:189889447-189889447	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1028G>A; p.R343Q; 3:189868615-189868615	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.453G>A; p.Q151Q; 3:189808400-189808400	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.836C>A; p.P279H; 3:189866751-189866751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.836C>A; p.P279H; 3:189866751-189866751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.836C>A; p.P279H; 3:189866751-189866751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1485T>G; p.I495M; 3:189886529-189886529	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.142G>T; p.E48*; 3:189737819-189737819	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.319A>G; p.M107V; 3:189738769-189738769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1110C>T; p.N370N; 3:189868697-189868697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.829G>T; p.E277*; 3:189866744-189866744	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1329C>G; p.H443Q; 3:189872975-189872975	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>T; p.A145V; 3:189808381-189808381	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.115A>G; p.T39A; 3:189737792-189737792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.531C>T; p.F177F; 3:189808478-189808478	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.531C>T; p.F177F; 3:189808478-189808478	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1780C>T; p.R594*; 3:189894239-189894239	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.796C>T; p.R266*; 3:189866711-189866711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.796C>T; p.R266*; 3:189866711-189866711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.521C>T; p.P174L; 3:189808468-189808468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1015T>C; p.C339R; 3:189868602-189868602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.302C>T; p.S101L; 3:189738752-189738752	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1129+1G>A; p.?; 3:189868717-189868717	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1094C>T; p.S365L; 3:189868681-189868681	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.569C>T; p.A190V; 3:189808516-189808516	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.983A>G; p.E328G; 3:189867933-189867933	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2039A>G; p.E680G; 3:189894498-189894498	liver	carcinoma	Substitution - Missense
c.1131G>A; p.P377P; 3:189869325-189869325	liver	carcinoma	Substitution - coding silent
c.1555C>T; p.L519F; 3:189889387-189889387	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1107G>C; p.K369N; 3:189868694-189868694	liver	carcinoma	Substitution - Missense
c.1107G>C; p.K369N; 3:189868694-189868694	liver	carcinoma	Substitution - Missense
c.522G>T; p.P174P; 3:189808469-189808469	liver	carcinoma	Substitution - coding silent
c.1016G>T; p.C339F; 3:189868603-189868603	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1885G>T; p.G629C; 3:189894344-189894344	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.432G>T; p.T144T; 3:189808379-189808379	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1971G>T; p.E657D; 3:189894430-189894430	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.516A>G; p.P172P; 3:189808463-189808463	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.806G>T; p.G269V; 3:189866721-189866721	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1964G>T; p.R655L; 3:189894423-189894423	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.468C>T; p.F156F; 3:189808415-189808415	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1257G>A; p.E419E; 3:189872903-189872903	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.551C>G; p.S184W; 3:189808498-189808498	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.455C>A; p.P152H; 3:189808402-189808402	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.982G>T; p.E328*; 3:189867932-189867932	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.157G>C; p.E53Q; 3:189737834-189737834	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1729G>C; p.E577Q; 3:189890865-189890865	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.521C>A; p.P174Q; 3:189808468-189808468	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1163C>T; p.T388I; 3:189869357-189869357	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.76C>G; p.P26A; 3:189737753-189737753	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.637A>T; p.I213F; 3:189864289-189864289	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.309G>C; p.L103L; 3:189738759-189738759	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1309C>A; p.Q437K; 3:189872955-189872955	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.14C>T; p.T5I; 3:189631529-189631529	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.510C>A; p.D170E; 3:189808457-189808457	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.731G>T; p.C244F; 3:189864383-189864383	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1227G>C; p.E409D; 3:189872873-189872873	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1065T>C; p.D355D; 3:189868652-189868652	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1090G>A; p.V364I; 3:189868677-189868677	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1049G>C; p.R350T; 3:189868636-189868636	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.404A>G; p.N135S; 3:189808351-189808351	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.N126N; 3:189808325-189808325	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1127G>A; p.R376H; 3:189868714-189868714	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1886G>A; p.G629D; 3:189894345-189894345	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1317A>G; p.Q439Q; 3:189872963-189872963	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1928G>A; p.R643Q; 3:189894387-189894387	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.985A>C; p.T329P; 3:189867935-189867935	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.319A>T; p.M107L; 3:189738769-189738769	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.392C>G; p.T131S; 3:189808339-189808339	ovary	other; neoplasm	Substitution - Missense
c.1909C>T; p.R637C; 3:189894368-189894368	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.469G>A; p.D157N; 3:189808416-189808416	pancreas	carcinoma	Substitution - Missense
c.376A>C; p.N126H; 3:189808323-189808323	pancreas	carcinoma	Substitution - Missense
c.941G>C; p.G314A; 3:189867891-189867891	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.677G>A; p.R226H; 3:189864329-189864329	prostate	adenoma	Substitution - Missense
c.2029G>A; p.E677K; 3:189894488-189894488	skin	malignant_melanoma	Substitution - Missense
c.852G>A; p.Q284Q; 3:189866767-189866767	skin	malignant_melanoma	Substitution - coding silent
c.797G>A; p.R266Q; 3:189866712-189866712	skin	malignant_melanoma	Substitution - Missense
c.1602C>T; p.T534T; 3:189889434-189889434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.57C>A; p.I19I; 3:189631572-189631572	skin	malignant_melanoma	Substitution - coding silent
c.700G>A; p.A234T; 3:189864352-189864352	skin	malignant_melanoma	Substitution - Missense
c.1743G>A; p.M581I; 3:189890879-189890879	skin	malignant_melanoma	Substitution - Missense
c.918C>T; p.F306F; 3:189867868-189867868	skin	malignant_melanoma	Substitution - coding silent
c.66C>T; p.F22F; 3:189737743-189737743	skin	malignant_melanoma	Substitution - coding silent
c.1995G>A; p.M665I; 3:189894454-189894454	skin	malignant_melanoma	Substitution - Missense
c.1617C>T; p.P539P; 3:189889449-189889449	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1301C>T; p.T434M; 3:189872947-189872947	skin	malignant_melanoma	Substitution - Missense
c.1747-1G>A; p.?; 3:189894205-189894205	skin	malignant_melanoma	Unknown
c.1166C>T; p.S389F; 3:189869360-189869360	skin	malignant_melanoma	Substitution - Missense
c.1679C>T; p.S560L; 3:189890815-189890815	skin	malignant_melanoma	Substitution - Missense
c.398C>T; p.P133L; 3:189808345-189808345	skin	malignant_melanoma	Substitution - Missense
c.766+1G>A; p.?; 3:189864419-189864419	skin; trunk	malignant_melanoma	Unknown
c.1698G>A; p.T566T; 3:189890834-189890834	skin	malignant_melanoma	Substitution - coding silent
c.1928G>A; p.R643Q; 3:189894387-189894387	skin	malignant_melanoma	Substitution - Missense
c.1928G>A; p.R643Q; 3:189894387-189894387	skin	malignant_melanoma	Substitution - Missense
c.1843C>T; p.H615Y; 3:189894302-189894302	skin	malignant_melanoma	Substitution - Missense
c.1221C>T; p.G407G; 3:189872867-189872867	skin	malignant_melanoma	Substitution - coding silent
c.806G>A; p.G269E; 3:189866721-189866721	skin	malignant_melanoma	Substitution - Missense
c.1416G>A; p.M472I; 3:189886460-189886460	skin	malignant_melanoma	Substitution - Missense
c.110G>A; p.R37Q; 3:189737787-189737787	skin	malignant_melanoma	Substitution - Missense
c.336G>A; p.T112T; 3:189808283-189808283	skin	malignant_melanoma	Substitution - coding silent
c.1938C>T; p.L646L; 3:189894397-189894397	skin	malignant_melanoma	Substitution - coding silent
c.336G>A; p.T112T; 3:189808283-189808283	skin	malignant_melanoma	Substitution - coding silent
c.1190A>G; p.D397G; 3:189869384-189869384	skin	malignant_melanoma	Substitution - Missense
c.1373C>T; p.S458L; 3:189886417-189886417	skin	malignant_melanoma	Substitution - Missense
c.579G>A; p.T193T; 3:189808526-189808526	skin	malignant_melanoma	Substitution - coding silent
c.1373C>T; p.S458L; 3:189886417-189886417	skin	malignant_melanoma	Substitution - Missense
c.1985A>G; p.N662S; 3:189894444-189894444	skin	malignant_melanoma	Substitution - Missense
c.1964G>A; p.R655Q; 3:189894423-189894423	skin	malignant_melanoma	Substitution - Missense
c.579+1G>A; p.?; 3:189808527-189808527	skin	malignant_melanoma	Unknown
c.349C>T; p.L117L; 3:189808296-189808296	skin	malignant_melanoma	Substitution - coding silent
c.1936C>G; p.L646V; 3:189894395-189894395	skin	malignant_melanoma	Substitution - Missense
c.387G>A; p.S129S; 3:189808334-189808334	skin	malignant_melanoma	Substitution - coding silent
c.150C>T; p.L50L; 3:189737827-189737827	skin	malignant_melanoma	Substitution - coding silent
c.642G>A; p.K214K; 3:189864294-189864294	skin	malignant_melanoma	Substitution - coding silent
c.1744G>A; p.D582N; 3:189890880-189890880	skin	malignant_melanoma	Substitution - Missense
c.348C>T; p.L116L; 3:189808295-189808295	skin	malignant_melanoma	Substitution - coding silent
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin; trunk	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.1135C>T; p.R379C; 3:189869329-189869329	skin	malignant_melanoma	Substitution - Missense
c.178G>A; p.D60N; 3:189737855-189737855	skin	malignant_melanoma	Substitution - Missense
c.178G>A; p.D60N; 3:189737855-189737855	skin	malignant_melanoma	Substitution - Missense
c.1161G>A; p.M387I; 3:189869355-189869355	skin	malignant_melanoma	Substitution - Missense
c.648G>A; p.M216I; 3:189864300-189864300	skin	malignant_melanoma	Substitution - Missense
c.648G>A; p.M216I; 3:189864300-189864300	skin	malignant_melanoma	Substitution - Missense
c.1161G>A; p.M387I; 3:189869355-189869355	skin; arm	malignant_melanoma	Substitution - Missense
c.397C>T; p.P133S; 3:189808344-189808344	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1889C>T; p.S630F; 3:189894348-189894348	skin	malignant_melanoma	Substitution - Missense
c.1872T>C; p.S624S; 3:189894331-189894331	skin	malignant_melanoma	Substitution - coding silent
c.1969G>A; p.E657K; 3:189894428-189894428	skin	malignant_melanoma	Substitution - Missense
c.508G>A; p.D170N; 3:189808455-189808455	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.508G>A; p.D170N; 3:189808455-189808455	skin	malignant_melanoma	Substitution - Missense
c.1255G>T; p.E419*; 3:189872901-189872901	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.488C>T; p.P163L; 3:189808435-189808435	skin	malignant_melanoma	Substitution - Missense
c.488C>T; p.P163L; 3:189808435-189808435	skin	malignant_melanoma	Substitution - Missense
c.1825G>A; p.E609K; 3:189894284-189894284	skin	malignant_melanoma	Substitution - Missense
c.1825G>A; p.E609K; 3:189894284-189894284	skin	malignant_melanoma	Substitution - Missense
c.1825G>A; p.E609K; 3:189894284-189894284	skin	malignant_melanoma	Substitution - Missense
c.1825G>A; p.E609K; 3:189894284-189894284	skin	malignant_melanoma	Substitution - Missense
c.665G>A; p.G222E; 3:189864317-189864317	skin	malignant_melanoma	Substitution - Missense
c.1825G>A; p.E609K; 3:189894284-189894284	skin; arm	malignant_melanoma	Substitution - Missense
c.1713C>A; p.T571T; 3:189890849-189890849	skin	malignant_melanoma	Substitution - coding silent
c.1575C>T; p.L525L; 3:189889407-189889407	skin	malignant_melanoma	Substitution - coding silent
c.1003C>T; p.L335L; 3:189868590-189868590	skin	malignant_melanoma	Substitution - coding silent
c.1664G>A; p.R555K; 3:189890800-189890800	skin	malignant_melanoma	Substitution - Missense
c.386C>T; p.S129L; 3:189808333-189808333	skin	malignant_melanoma	Substitution - Missense
c.1747G>A; p.D583N; 3:189894206-189894206	skin	malignant_melanoma	Substitution - Missense
c.1747G>A; p.D583N; 3:189894206-189894206	skin	malignant_melanoma	Substitution - Missense
c.390C>T; p.S130S; 3:189808337-189808337	skin	malignant_melanoma	Substitution - coding silent
c.948G>A; p.M316I; 3:189867898-189867898	skin	malignant_melanoma	Substitution - Missense
c.1218G>A; p.R406R; 3:189872864-189872864	skin	malignant_melanoma	Substitution - coding silent
c.540C>T; p.S180S; 3:189808487-189808487	skin	malignant_melanoma	Substitution - coding silent
c.1973G>A; p.W658*; 3:189894432-189894432	skin	malignant_melanoma	Substitution - Nonsense
c.1009C>T; p.R337*; 3:189868596-189868596	skin	malignant_melanoma	Substitution - Nonsense
c.147C>T; p.F49F; 3:189737824-189737824	skin	malignant_melanoma	Substitution - coding silent
c.1448A>G; p.N483S; 3:189886492-189886492	skin	malignant_melanoma	Substitution - Missense
c.409G>A; p.D137N; 3:189808356-189808356	skin	malignant_melanoma	Substitution - Missense
c.1349+3G>A; p.?; 3:189872998-189872998	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.298G>A; p.D100N; 3:189738748-189738748	skin	malignant_melanoma	Substitution - Missense
c.1178G>A; p.R393Q; 3:189869372-189869372	skin	malignant_melanoma	Substitution - Missense
c.1576C>T; p.P526S; 3:189889408-189889408	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1576C>T; p.P526S; 3:189889408-189889408	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1576C>T; p.P526S; 3:189889408-189889408	skin	malignant_melanoma	Substitution - Missense
c.532G>A; p.D178N; 3:189808479-189808479	skin	malignant_melanoma	Substitution - Missense
c.217G>A; p.D73N; 3:189738667-189738667	skin	malignant_melanoma	Substitution - Missense
c.982G>A; p.E328K; 3:189867932-189867932	skin	malignant_melanoma	Substitution - Missense
c.97G>A; p.E33K; 3:189737774-189737774	skin	malignant_melanoma	Substitution - Missense
c.1122G>A; p.T374T; 3:189868709-189868709	skin	malignant_melanoma	Substitution - coding silent
c.2021G>A; p.R674H; 3:189894480-189894480	skin	malignant_melanoma	Substitution - Missense
c.1002C>T; p.V334V; 3:189868589-189868589	skin	malignant_melanoma	Substitution - coding silent
c.1046G>A; p.G349E; 3:189868633-189868633	skin	malignant_melanoma	Substitution - Missense
c.50C>T; p.P17L; 3:189631565-189631565	skin	malignant_melanoma	Substitution - Missense
c.621G>A; p.K207K; 3:189864273-189864273	skin	malignant_melanoma	Substitution - coding silent
c.531C>T; p.F177F; 3:189808478-189808478	skin	malignant_melanoma	Substitution - coding silent
c.1780C>T; p.R594*; 3:189894239-189894239	skin	malignant_melanoma	Substitution - Nonsense
c.1780C>T; p.R594*; 3:189894239-189894239	skin	malignant_melanoma	Substitution - Nonsense
c.1598C>T; p.S533F; 3:189889430-189889430	skin	malignant_melanoma	Substitution - Missense
c.1788G>A; p.A596A; 3:189894247-189894247	skin	malignant_melanoma	Substitution - coding silent
c.1848C>T; p.L616L; 3:189894307-189894307	skin	malignant_melanoma	Substitution - coding silent
c.1848C>T; p.L616L; 3:189894307-189894307	skin	malignant_melanoma	Substitution - coding silent
c.3G>A; p.M1I; 3:189631518-189631518	skin	malignant_melanoma	Substitution - Missense
c.1094C>T; p.S365L; 3:189868681-189868681	skin	malignant_melanoma	Substitution - Missense
c.1094C>T; p.S365L; 3:189868681-189868681	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.1094C>T; p.S365L; 3:189868681-189868681	skin	malignant_melanoma	Substitution - Missense
c.1740C>T; p.S580S; 3:189890876-189890876	skin	malignant_melanoma	Substitution - coding silent
c.1094C>T; p.S365L; 3:189868681-189868681	skin; arm	malignant_melanoma	Substitution - Missense
c.1094C>T; p.S365L; 3:189868681-189868681	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1934_1935CC>TT; p.T645I; 3:189894393-189894394	skin	malignant_melanoma	Substitution - Missense
c.675C>T; p.I225I; 3:189864327-189864327	skin	malignant_melanoma	Substitution - coding silent
c.1497G>T; p.M499I; 3:189886541-189886541	skin	malignant_melanoma	Substitution - Missense
c.1497G>T; p.M499I; 3:189886541-189886541	skin	malignant_melanoma	Substitution - Missense
c.62+2T>C; p.?; 3:189631579-189631579	stomach	carcinoma; adenocarcinoma	Unknown
c.713C>T; p.T238M; 3:189864365-189864365	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.415G>A; p.A139T; 3:189808362-189808362	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.453G>T; p.Q151H; 3:189808400-189808400	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1415T>C; p.M472T; 3:189886459-189886459	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.807G>A; p.G269G; 3:189866722-189866722	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.694delA; p.A234fs*8; 3:189864346-189864346	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1615delC; p.P540fs*14; 3:189889447-189889447	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.566C>T; p.S189L; 3:189808513-189808513	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.861G>A; p.L287L; 3:189866776-189866776	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1657T>A; p.L553I; 3:189890793-189890793	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.275G>T; p.S92I; 3:189738725-189738725	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1780C>T; p.R594*; 3:189894239-189894239	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.507C>T; p.T169T; 3:189808454-189808454	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1580C>T; p.P527L; 3:189889412-189889412	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.690C>T; p.V230V; 3:189864342-189864342	thyroid	other; neoplasm	Substitution - coding silent
c.222G>C; p.L74F; 3:189738672-189738672	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.222G>C; p.L74F; 3:189738672-189738672	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.222G>C; p.L74F; 3:189738672-189738672	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1173G>A; p.K391K; 3:189869367-189869367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.340C>G; p.L114V; 3:189808287-189808287	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.926A>G; p.N309S; 3:189867876-189867876	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.568G>C; p.A190P; 3:189808515-189808515	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.178G>A; p.D60N; 3:189737855-189737855	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1227G>A; p.E409E; 3:189872873-189872873	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1361A>G; p.Q454R; 3:189886405-189886405	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.242C>G; p.S81*; 3:189738692-189738692	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1049G>A; p.R350K; 3:189868636-189868636	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.945G>A; p.G315G; 3:189867895-189867895	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.551C>T; p.S184L; 3:189808498-189808498	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.507C>T; p.T169T; 3:189808454-189808454	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.507C>T; p.T169T; 3:189808454-189808454	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1129+8G>C; p.?; 3:189868724-189868724	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1697C>T; p.T566M; 3:189890833-189890833	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142G>A; p.E48K; 3:189737819-189737819	urinary_tract; bladder	carcinoma	Substitution - Missense
c.97G>C; p.E33Q; 3:189737774-189737774	urinary_tract; bladder	carcinoma	Substitution - Missense
c.97G>C; p.E33Q; 3:189737774-189737774	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.46G>A; p.D16N; 3:189631561-189631561	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1010G>A; p.R337Q; 3:189868597-189868597	urinary_tract; bladder	carcinoma	Substitution - Missense
c.173T>C; p.I58T; 3:189737850-189737850	urinary_tract; bladder	carcinoma	Substitution - Missense
c.461C>T; p.S154F; 3:189808408-189808408	urinary_tract; bladder	carcinoma	Substitution - Missense
c.461C>T; p.S154F; 3:189808408-189808408	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.509A>T; p.D170V; 3:189808456-189808456	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.509A>T; p.D170V; 3:189808456-189808456	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3G>A; p.M1I; 3:189631518-189631518	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

Bioinformatics and cancer genomics links

Bioinformatics centers

Bioinformatics centers

Welcome to Bioinfo-MinZhao!